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Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A*STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population.

26 Apr 2024

Owlstone Medical secures $6.5 million to support development of breath-based diagnostics for infectious disease

Funding represents the first time the foundation has taken an equity position in a breath diagnostics company.

From Owlstone Medical Ltd 25 Apr 2024

Genetics studies have a diversity problem that researchers struggle to fix

When he recently walked into the dental clinic at the Medical University of South Carolina donning a bright-blue pullover with "In Our DNA SC" embroidered prominently on the front, Lee Moultrie said, two Black women stopped him to ask questions.

25 Apr 2024

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

The role of neighborhood-level disparities in determining shorter breast cancer-specific survival.

22 Apr 2024

Top pharmaceutical company evaluates Optimer for precision liver medicine

Optimer delivery vehicle has been shipped to a pharma partner for external evaluation.

From Aptamer Group 22 Apr 2024

Breakthrough imaging method enhances precision in prostate cancer treatment

A novel SPECT/CT acquisition method can accurately detect radiopharmaceutical biodistribution in a convenient manner for prostate cancer patients, opening the door for more personalized treatment.

17 Apr 2024

Study suggests a promising new approach to understanding autism

Autism spectrum disorder has yet to be linked to a single cause, due to the wide range of its symptoms and severity.

17 Apr 2024

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

In an ambitious new study, a research team that included scientists from Yale set out to uncover potential treatments for patients with rare neuroendocrine tumors of the cervix (NETc) by understanding the molecular basis of the aggressive disease.

17 Apr 2024

Early life stress may underlie a pathophysiological exacerbation of postpartum depression

In a new study, a Johns Hopkins Medicine-led research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.

16 Apr 2024

Placental IGFBP1: A key factor in development of gestational diabetes

A new study led by the Harvard Pilgrim Health Care Institute has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

16 Apr 2024

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

How muscle changes with aging, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of aging muscles in humans.

15 Apr 2024

Cas13d-NCS: A game-changer in RNA virus defense

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate.

13 Apr 2024

PET/MRI combination reduces unnecessary prostate biopsies, study shows

PET/MRI can improve diagnostic accuracy for prostate cancer patients and help avoid unnecessary biopsies, according to new research published in the April issue of The Journal of Nuclear Medicine.

13 Apr 2024

Innovative cancer treatment approach yields promising results in pediatric patients

Researchers have developed a functional precision medicine approach that targets cancer by combining genetic testing with a new way to test individual drugs on tumor samples.

12 Apr 2024

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Sex differences are widespread across human development, physiological processes, and diseases, making it important to characterize the impact of sex differences in these areas.

12 Apr 2024

New review explores the key gender differences in sleep, circadian rhythms and metabolism

A new review of research evidence has explored the key differences in how women and men sleep, variations in their body clocks, and how this affects their metabolism.

12 Apr 2024

Researchers develop first genetic maps for disease-linked DNA repeats

A research team led by the University of California, Irvine has built the first genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington's disease and multiple cancers.

5 Apr 2024

Precision Medicine News and Research

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

Owlstone Medical secures $6.5 million to support development of breath-based diagnostics for infectious disease

Genetics studies have a diversity problem that researchers struggle to fix

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

Top pharmaceutical company evaluates Optimer for precision liver medicine

Breakthrough imaging method enhances precision in prostate cancer treatment

Study suggests a promising new approach to understanding autism

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

Early life stress may underlie a pathophysiological exacerbation of postpartum depression

Placental IGFBP1: A key factor in development of gestational diabetes

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

Cas13d-NCS: A game-changer in RNA virus defense

PET/MRI combination reduces unnecessary prostate biopsies, study shows

Innovative cancer treatment approach yields promising results in pediatric patients

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

New review explores the key gender differences in sleep, circadian rhythms and metabolism

Researchers develop first genetic maps for disease-linked DNA repeats

Non-invasive detection and treatment of ovarian cancer with new radiotheranostic system

Advances and hurdles: The impact of AI on oncology care efficiency and mortality rates

AI-based tool revolutionizes prediction of immune response to cancer

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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