Primary Biliary Cirrhosis News and Research

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Primary biliary cirrhosis is a chronic disease that causes the bile ducts in the liver to become inflamed and damaged and, ultimately, disappear. Bile is a liquid produced in the liver that travels through the bile ducts to the gallbladder and then the small intestine, where it helps digest fats and fat-soluble vitamins A, D, E, and K. When the bile ducts become damaged from chronic inflammation, bile builds up in the liver, injuring liver tissue.
Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists develop promising new test to identify patients with rare liver disease

Scientists discover link between two genes involved in PD and autoimmune diseases

Scientists discover link between two genes involved in PD and autoimmune diseases

WFA+-M2BP levels linked to liver fibrosis, HCC progression in chronic HBV

WFA+-M2BP levels linked to liver fibrosis, HCC progression in chronic HBV

Tioga Pharmaceuticals announces commencement of asimadoline Phase 2 study for treatment of pruritus

Tioga Pharmaceuticals announces commencement of asimadoline Phase 2 study for treatment of pruritus

Phase 2 IMAGO trial of SHP625 fails to meet primary endpoints in pediatric patients with ALGS

Phase 2 IMAGO trial of SHP625 fails to meet primary endpoints in pediatric patients with ALGS

Betaretrovirus may infect patients with primary biliary cirrhosis

Betaretrovirus may infect patients with primary biliary cirrhosis

State highlights: Rural telemedicine; two Iowa planned parenthoods closed

State highlights: Rural telemedicine; two Iowa planned parenthoods closed

Obeticholic acid meets primary composite endpoint in Phase III study

Obeticholic acid meets primary composite endpoint in Phase III study

Soligenix initiates orBec Phase 2 study for GI manifestations of chronic GVHD

Soligenix initiates orBec Phase 2 study for GI manifestations of chronic GVHD

Lumena Pharmaceuticals initiates LUM001 clinical program in children with ALGS

Lumena Pharmaceuticals initiates LUM001 clinical program in children with ALGS

Intercept Pharmaceuticals reports financial results for Second quarter 2013

Intercept Pharmaceuticals reports financial results for Second quarter 2013

Par Pharmaceutical receives final ANDA approval for generic version of Trilipix

Par Pharmaceutical receives final ANDA approval for generic version of Trilipix

Researchers link coffee consumption with reduced risk of primary sclerosing cholangitis

Researchers link coffee consumption with reduced risk of primary sclerosing cholangitis

Early PBC prognosis advocated

Early PBC prognosis advocated

FDA grants Albireo's A4250 orphan-drug designation for treatment of PFIC and PBC

FDA grants Albireo's A4250 orphan-drug designation for treatment of PFIC and PBC

Researchers identify three genetic regions associated with primary biliary cirrhosis

Researchers identify three genetic regions associated with primary biliary cirrhosis

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

EMA COMP issues positive opinion to Albireo for A4250

EMA COMP issues positive opinion to Albireo for A4250

Rituximab shows promise against primary biliary cirrhosis

Rituximab shows promise against primary biliary cirrhosis

Liver transplantations for NASH-Cirrhosis increase dramatically

Liver transplantations for NASH-Cirrhosis increase dramatically