Progenitor Cells News and Research

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Study sheds new insight into the dynamics of neural stem cell niche

When it comes to cell types, stem cells have unlimited potential – literally. These self-renewing cells, which are capable of giving rise to any cell type in the body, reside in specialized microenvironments known as niches.

16 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

Pluripotent stem cells can be a limitless source of transplantable HSPCs

Cells in the blood such as immune cells, red blood cells and other vital cell types are constantly renewed from stem cells, the so-called hematopoietic stem and progenitor cells (HSPCs).

19 Feb 2023

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against SARS-CoV-2.

3 Feb 2023

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

A University of Alberta researcher is one step closer to demonstrating the potential of a brain molecule called fractalkine to halt and even reverse the effects of multiple sclerosis and other neurodegenerative diseases.

1 Feb 2023

New research changes the paradigm of how people think about graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

30 Jan 2023

Study suggests cortical hemorrhage in fetal brain may be associated with COVID-19

Researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on fetal brain health.

25 Jan 2023

How does the brain change with age?

Researchers discussed cellular hallmarks of brain aging and therapeutic interventions to rejuvenate cognitive brain functions.

19 Jan 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

Acquired mutations in 'Guardian of the Genome' accelerate the development of atherosclerosis

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in collaboration with institutes in the USA, has demonstrated that acquired mutations in the gene encoding the protein p53 contribute to the development of atherosclerotic cardiovascular disease.

16 Jan 2023

New electrically conductive hydrogel scaffold supports neural cell differentiation

Brain-computer interfaces (BCIs) are a hot topic these days, with companies like Neuralink racing to create devices that connect humans' brains to machines via tiny implanted electrodes.

5 Jan 2023

Scientists find key reason for ongoing loss of smell in long-COVID

In a recent study published in the journal Science Translational Medicine, researchers reported that long-term anosmia following coronavirus disease 2019 (COVID-19) could be a result of persistent T-cell mediated inflammation occurring in the olfactory epithelium even after the elimination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the olfactory tissue.

27 Dec 2022

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

In the annals of shoulder surgery, NFL quarterback Drew Brees is an anomaly. In 2005, Brees was tackled and the rotator cuff tendon in his throwing shoulder was severely torn, a potentially career-ending injury.

16 Dec 2022

Expansion of intermediate cells in prostate cancer correlates with treatment resistance and poor outcomes

Researchers have characterised prostate cancer cell dynamics at a single-cell resolution across the timespan of the disease – from its beginning to the point of androgen independence, where the tumour no longer responds to hormone deprivation therapy.

14 Dec 2022

Progenitor Cells News and Research

Study sheds new insight into the dynamics of neural stem cell niche

Embryonic stem cells used to recreate thyroid cancer histotypes

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Pluripotent stem cells can be a limitless source of transplantable HSPCs

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

New research changes the paradigm of how people think about graft-versus-host disease

Study suggests cortical hemorrhage in fetal brain may be associated with COVID-19

How does the brain change with age?

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Acquired mutations in 'Guardian of the Genome' accelerate the development of atherosclerosis

New electrically conductive hydrogel scaffold supports neural cell differentiation

Scientists find key reason for ongoing loss of smell in long-COVID

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

Expansion of intermediate cells in prostate cancer correlates with treatment resistance and poor outcomes

An epigenetic modification improves the defense against infections, research shows

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

The potential of Sofosbuvir against COVID-19 neurological symptoms

Parasites associated with leprosy may have the ability to regenerate livers

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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