Progeria News and Research

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PCORI Board approves $70 million to support projects designed to improve care for health conditions

The Patient-Centered Outcomes Research Institute Board of Governors today approved $70 million to fund 21 studies and related projects designed to improve care for health conditions that impose high burdens on patients, their families and the healthcare system.

19 Nov 2019

Potential new therapy for progeria

Aging is a complex and natural process that affects all living organisms. As people age, normal biological processes are affecting, resulting in a decline in various organs and age-related conditions. Though aging is normal, some children affected by a disease called Progeria may age way faster than others.

18 Nov 2019

Study presents a new view on how mitochondrial dysfunction may contribute to aging

Disturbances in the function of mitochondrial DNA can accelerate the aging process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism.

8 Oct 2019

Researchers develop new technology to study cell nanomechanics

Researchers at Singapore-MIT Alliance for Research and Technology and MIT's Laser Biomedical Research Center have developed a new way to study cells, paving the way for a better understanding of how cancers spread and become killers.

20 Sep 2019

SATI gene editing could replace CRISPR

Scientists have developed a new gene editing tool called SATI that is safer than CRISPR.

2 Sep 2019

New molecules that could help tackle tooth loss and regeneration discovered

Our teeth take thousands of bites per day, and understanding exactly what holds them in place and how is key to helping people live with their own teeth for longer.

30 Aug 2019

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

Human iPSCs make more tiny 'cargo packets' to deliver cellular aging therapies

Johns Hopkins scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells, make tiny "cargo packets" able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells.

From Johns Hopkins Medicine 8 May 2019

Researchers identify potential therapeutic target for blocking early atherosclerosis in progeria

Researchers at the Centro Nacional de Investigaciones Cardiovasculares and the Universidad de Oviedo have discovered a new molecular mechanism involved in the premature development of atherosclerosis in mice with Hutchinson-Gilford progeria syndrome.

12 Mar 2019

Newly developed gene therapy helps decelerate aging process

Aging is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer's disease, to name a few. This makes the need for anti-aging therapies all the more urgent. Now, Salk Institute researchers have developed a new gene therapy to help decelerate the aging process.

20 Feb 2019

Blood cells could hold the key to aging

Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine.

8 Feb 2019

Scientists reveal molecular mechanism behind CVD in premature aging disease

Cardiovascular Diseases lead to atherosclerosis and heart failure and are prevalent age-related illnesses in humans. In a new study, published in the renowned journal JCI, scientists from Roland Foisner's group at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna, together with scientists from the Ludwig Boltzmann Cluster for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna and from the BOKU, Vienna describe the molecular mechanism behind CVD in the premature aging disease Hutchinson-Gilford progeria syndrome.

8 Jan 2019

Study lays foundation for addressing unresolved questions in human aging

Doctors have long observed that biological age and chronological age are not always one and the same. A 55-year-old may exhibit many signs of old age and have numerous age-related diseases, whereas an 80-year-old may be healthy and robust.

20 Dec 2018

Scientists synthesize new compound with anticarcinogenic properties

The patent has been registered from the University of Seville and licensed by the British company Evgen Pharma, which is currently developing programmes aimed at breast cancer, subarachnoid haemorrhage and multiple sclerosis, among others

5 Jul 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

Scientists discover potential therapeutic target for devastating premature aging disease

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterized by premature aging.

27 Apr 2018

Scientists uncover new answers to cell aging in children with rare, fatal disease

In a recent paper published in Cell Reports, Saint Louis University researchers have uncovered new answers about why cells rapidly age in children with a rare and fatal disease.

20 Mar 2018

Scientists identify protein biomarkers to track patients with Hutchinson-Gilford progeria syndrome

Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare fatal genetic disorder which causes sufferers to age prematurely.

19 Jan 2018

FSU researchers solve puzzle posed by family of rare premature aging disorders

New research from Florida State University is beginning to piece together the stubborn puzzle posed by a family of rare and debilitating premature aging disorders.

28 Nov 2017

Lab-grown miniature blood vessels mimic rare Hutchinson-Gilford Progeria Syndrome

Biomedical engineers have grown miniature human blood vessels that exhibit many of the symptoms and drug reactions associated with Hutchinson-Gilford Progeria Syndrome -- an extremely rare genetic disease that causes symptoms resembling accelerated aging in children.

16 Aug 2017