Protein Engineering News and Research

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Nanoscale mechanism to externally control the function and action of a protein

"We can switch a protein on and off, and while we have controlled a specific protein, we believe our approach will work with virtually any protein," said Giovanni Zocchi, assistant professor of physics at UCLA, member of the California NanoSystems Institute and leader of the research effort. "This research has the potential to start a new approach to protein engineering."

16 Feb 2005

Nanoscale switch could serve as sensor, medical tool

Improving significantly on an early prototype, Johns Hopkins University researchers have found a new way to join two unrelated proteins to create a molecular switch, a nanoscale "device" in which one biochemical partner controls the activity of the other.

29 Nov 2004

Family experience guides Alzheimer’s research

After watching his father struggle with and ultimately succumb to Alzheimer’s disease, ASU professor Michael Sierks shifted his research focus from starch hydrolyzing to neurodegenerative diseases.

18 Nov 2004

Resveratrol in red wine, is thought to contribute to improved cardiovascular effects associated with moderate consumption of red wine

Researchers funded by the National Science Foundation (NSF) and affiliated with the Salk Institute in San Diego, Calif., have succeeded in converting chalcone synthase, a biosynthetic protein enzyme found in all higher plants, into an efficient resveratrol synthase.

20 Sep 2004

Japanese research lab to use an IBM supercomputer for protein research

IBM announced today that AIST, a leading Japanese research laboratory, will use an IBM BlueGene/L supercomputer to advance their research in proteins, potentially accelerating breakthroughs in drug design. The BlueGene/L supercomputer has been ranked as the fourth largest supercomputer in the world.

8 Sep 2004

International research sheds light on Escherichia coli

An unprecedented picture of how bacteria latch on to human cells has been published by UK, French and US scientists. They have produced a finely detailed model of one of the tools used by some of the nastiest varieties of the stomach bug, Escherichia coli, to stick to and gain entry to host cells.

1 Sep 2004

Experimental vaccine against ricin

Scientists have developed an experimental vaccine against ricin, a potential biological threat agent, which fully protected mice from aerosol challenge with lethal doses of the toxin.

5 Aug 2004

Australia's CSIRO to exhibit major display at the world's largest biotechnology conference

CSIRO is mounting a major display of technologies this week at BIO 2004, the world's largest biotechnology conference, being held in San Francisco, USA, from 6-9 June.

7 Jun 2004

Compounds that may stop replication of T-cell leukemia virus

Researchers are analyzing several compounds that may inhibit the enzyme that is essential for the reproduction of the Human T-cell Leukemia Virus Type 1 (HTLV-I), which has infected 15 to 20 million people worldwide. The virus causes the fatal adult T-cell leukemia in up to 10 percent of those infected.

1 Apr 2004