Protein Expression News and Research

RSS

Zebrafish shed light on human mitochondrial diseases

Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders, according to researchers at the University of Oregon.

13 Sep 2007

Reactivating a critical gene lost in kidney cancer reduces tumor growth

Researchers at Mayo Clinic Jacksonville, have found that a key gene is often silenced in clear cell renal cell carcinoma, the most common type of kidney cancer, and when they restored that gene in human kidney cancer cells in culture and animal experiments, tumors stopped growing and many disappeared.

17 Aug 2007

BRCA2 carriers more likely to develop aggressive and lethal prostate cancer

Carriers of a BRCA2 variation specific to Iceland are more likely to develop aggressive and lethal prostate cancer than noncarriers, according to a study published online in the Journal of the National Cancer Institute.

14 Jun 2007

Some NSAIDs may be better suited to treating cancer

Until recently, nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and celecoxib (sold as Celebrex), were being hailed as promising cancer prevention drugs.

18 May 2007

Global heartbeat control suggests therapy for beating heart failure

Keeping a healthy heart beating requires the production of a constant supply of energy, a feat depending on the coordination of several genetic programs.

9 May 2007

How inhaled anthrax paralyzes the body's defenses

University of Florida researchers have revealed how the inhaled form of anthrax paralyzes the body's defenses and prevents immune cells from reaching the site of infection.

8 May 2007

Curcumin has anticancer effects

Curry powder is a mixture predominantly composed of turmeric root extract and other spices such as coriander and fenugreek.

14 Apr 2007

Severe reduction of Treg cells may be involved in development of pemphigus vulgaris

Several T cell subsets with immunosuppressive functions have been reported to demonstrate their suppressive capabilities to the acquired immune system in animal autoimmune disease models.

5 Apr 2007

Molecular mechanism involved in development of schizophrenia

In studying the postmortem brain tissue of adults who had been diagnosed with schizophrenia, the researchers found that levels of certain gene-regulating molecules called microRNAs were lower among schizophrenia patients than in persons who were free of psychiatric illness.

30 Mar 2007

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

In attempt to identify biological markers, or biomarkers, that can signal the presence of cancer and help oncologists determine the best course of therapy when cancer is present, teams of investigators are scouring stored tissue samples obtained from thousands of cancer patients.

4 Dec 2006

Why organs fail following massive trauma

Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human.

17 Oct 2006

New cell-based targets for treating autoimmune inflammatory diseases

Patients with systemic autoimmune diseases such as lupus and rheumatoid arthritis (RA) often suffer loss of kidney function.

31 Aug 2006

Finding opens new pathways for treating or preventing autoimmune diseases

A rare genetic defect that can trigger a host of diseases from type 1 diabetes to alopecia has helped explain the imbalance of immune regulator and killer cells in autoimmune disease.

31 May 2006

Unique protein expression could serve as a screening test for head and neck cancers

The blood of patients with head and neck cancer appears to have unique patterns of protein expression that one day could serve as a screening test for the highly aggressive cancer that is often diagnosed too late, researchers say.

10 May 2006

Real-time molecule-by-molecule "movie" of protein production in live cells

Chemists at Harvard University have developed the first technique providing a real-time, molecule-by-molecule "movie" of protein production in live cells.

19 Mar 2006

Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Researchers find a way to make plants produce more antigens needed for vaccines

Scientists have developed a new kind of molecule which they believe could ultimately lead to the development of a vaccine against HIV using genetically modified tobacco.

13 Mar 2006

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Newly identified protein may help improve treatment for lung cancer

Researchers hope that a newly identified protein can one day help improve treatment for lung cancer. The findings are reported by researchers from Wake Forest University School of Medicine and colleagues in the Journal of the National Cancer Institute.

21 Nov 2005

New method to find deadly malaria parasite

Researchers at UCSD have discovered that the single-cell parasite responsible for an estimated 1 million deaths per year worldwide from malaria has protein "wiring" that differs markedly from the cellular circuitry of other higher organisms

3 Nov 2005