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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''
New approach to handle people with dementia may help reduce use of antipsychotics drugs

New approach to handle people with dementia may help reduce use of antipsychotics drugs

A new approach to handling agitation, aggression and other unwanted behaviors by people with dementia may help reduce the use of antipsychotics and other psychiatric drugs in this population, and make life easier for them and their caregivers, a team of experts says. [More]

New approach may help reduce use of antipsychotics and other psychiatric drugs in dementia patients

A new approach to handling agitation, aggression and other unwanted behaviors by people with dementia may help reduce the use of antipsychotics and other psychiatric drugs in this population, and make life easier for them and their caregivers, a team of experts says. [More]
Study finds that baclofen drug has potential to prevent cocaine relapse

Study finds that baclofen drug has potential to prevent cocaine relapse

Relapse is the most painful and expensive feature of drug addiction-even after addicted individuals have been drug-free for months or years, the likelihood of sliding back into the habit remains high. The National Institute on Drug Abuse estimates that 40 to 60 percent of addicted individuals will relapse, and in some studies the rates are as high as 80 percent at six months after treatment. [More]

Cognitive deficits in bipolar patients ‘not homogenous’

Patients with bipolar disorder can be separated into three groups based on their cognitive performance, a study suggests. [More]
Lack of insight linked to disengagement with CBT for psychosis

Lack of insight linked to disengagement with CBT for psychosis

Lack of insight, poor social functioning and negative symptoms help to predict which patients will drop out of cognitive behavioural therapy for psychosis, say researchers. [More]

Affective and non-affective psychoses show rural-urban variation

Rates of affective psychosis appear to be increased in more urbanised areas, study findings from France show. [More]

First contact with psychiatric specialists hastens schizophrenia treatment

Patients with first-onset psychosis wait less time for treatment if they visit emergency clinics staffed by specialist psychiatric teams than their counterparts who access healthcare in community settings, report researchers. [More]

Six dimensions explain mania symptom variability

Researchers have identified a six-factor latent structure that they say best describes the symptomatology of hospitalized patients with bipolar mania. [More]

Researchers estimate psychosis rates in epilepsy

Patients with epilepsy are nearly eight times more likely than people without the condition to experience psychosis, show results of a systematic review and meta-analysis. [More]

Primary negative symptoms worsen functioning in schizophrenia

Primary negative symptoms adversely affect social, vocational and recreational functioning in patients with schizophrenia, even when the potential influence of secondary negative symptoms has been accounted for, Canadian researchers report. [More]
Study examines costs linked with specific inpatient mental health diagnoses for children

Study examines costs linked with specific inpatient mental health diagnoses for children

Nearly one in 10 hospitalized children have a primary diagnosis of a mental health condition, and depression alone accounts for $1.33 billion in hospital charges annually, according to a new analysis led by UCSF Benioff Children's Hospital. [More]
Dampened reward response tied to schizophrenia risk

Dampened reward response tied to schizophrenia risk

The striatal hypoactivation during reward anticipation seen in patients with schizophrenia is also present in their unaffected first-degree relatives, research shows. [More]

EEG-based biomarker can help predict psychotic disorder in high-risk individuals

Only one third of individuals identified as being at clinical high risk for psychosis actually convert to a psychotic disorder within a 3 year follow-up period. This risk assessment is based on the presence of sub-threshold psychotic-like symptoms. [More]

Stress sensitivity adds to psychosis vulnerability

Sensitivity to stress may help to determine whether traumatic life events will lead to psychosis, research suggests. [More]

Innovative study uses pharmacogenomic test to treat patients with psychotic disorders

ValueOptions, Inc. a health improvement company specializing in mental and emotional well-being and recovery, and Genomind, a personalized medicine company, today announced an innovative study that uses pharmacogenomic testing to treat patients diagnosed with psychotic disorders, including schizophrenia and bipolar disorder. [More]

Neurocognition, negative symptom effects in psychotic prodrome clarified

The contribution of neurocognition and negative symptoms to impaired social and role functioning in patients at clinical high risk of psychosis is important enough to warrant targeting both with therapeutic interventions, say researchers. [More]

Inflammation and stress combine in bipolar and schizophrenia subtypes

Researchers have found that some individuals with bipolar disorder or schizophrenia have combined stress response and immune dysfunctions. [More]

Drug abuse does not always lead to psychosis readmission

Cannabis or stimulant abuse disorders do not necessarily predict a negative outcome for patients with first-episode psychosis, Australian researchers report. [More]
ACADIA Pharmaceuticals proposes to sell common stock in underwritten public offering

ACADIA Pharmaceuticals proposes to sell common stock in underwritten public offering

ACADIA Pharmaceuticals Inc. (NASDAQ: ACAD) today announced that it intends to offer and sell, subject to market and other conditions, $150,000,000 of shares of its common stock in an underwritten public offering. [More]

Further support for hippocampal volume as psychosis biomarker

Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes provide further evidence that reduced hippocampal volume is a consistent feature of schizophrenia. [More]