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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''
Social environment not linked to UHR psychosis transition

Social environment not linked to UHR psychosis transition

Research indicates that social deprivation and migrant status do not influence the risk of transition to psychosis in ultra-high-risk individuals. [More]
National survey shows decrease in alcohol, cigarette and illicit drug use among U.S. teens

National survey shows decrease in alcohol, cigarette and illicit drug use among U.S. teens

A national survey of students in U.S. middle schools and high schools shows some important improvements in levels of substance use. [More]
Psychotic experiences show shared genetic liability

Psychotic experiences show shared genetic liability

Study findings provide support for psychotic experiences being an early marker of increased risk of psychosis transition and an important intermediary phenotype in transdiagnostic research on psychosis. [More]
Cerebellar cortical volume reduction specific to schizophrenia

Cerebellar cortical volume reduction specific to schizophrenia

Reduced cerebellar cortical volume occurs only in patients with schizophrenia, rather than all those with psychosis, say researchers. [More]
Study highlights causes of postpartum disorders in new mothers

Study highlights causes of postpartum disorders in new mothers

In the days shortly after giving birth, most mothers experience a period of increased calmness and decreased stress responses, but around 20% of mothers experience anxiety. Some women may become depressed, and around one in a thousand can develop psychosis. The latest evidence indicates that these distressing responses to motherhood are still poorly understood, but that animal research could provide valuable clues to their causes. [More]
University of Miami researcher reveals association between 'salience processing' and brain disorders

University of Miami researcher reveals association between 'salience processing' and brain disorders

How does the brain determine what matters? According to a new scientific article, a brain structure called the insula is essential for selecting things out of the environment that are "salient" for an individual, and dysfunction of this system is linked to brain disorders such as autism, psychosis and dementia. [More]
Primary care can help tackle mental health care disparities among ethnic minorities

Primary care can help tackle mental health care disparities among ethnic minorities

Primary care that includes mental health screenings and treatments that take into account a patient's language and cultural background can help address mental health care disparities among ethnic minorities, according to psychologists, physicians and other health care experts writing in a special issue of Psychological Services, published by the American Psychological Association. [More]
People with first-episode psychosis may benefit from medication treatment changes, study finds

People with first-episode psychosis may benefit from medication treatment changes, study finds

Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment, researchers have found. Current guidelines emphasize low doses of antipsychotic drugs and strategies for minimizing the side effects that might contribute to patients stopping their medication. [More]
EMAHSN extends IPS scheme to support people with mental health illness

EMAHSN extends IPS scheme to support people with mental health illness

The 8 December will see the first step in an East Midlands wide approach to supporting people with mental health illness back in to work or education. The East Midlands Academic Health Science Network is championing and extending a widely proven scheme called Individual Placement and Support (IPS) across the region. [More]
Psychopathology persists in ultra-high-risk psychosis patients

Psychopathology persists in ultra-high-risk psychosis patients

Patients at ultra-high-risk for psychosis frequently have nonpsychotic disorders and often continue to experience attenuated psychotic symptoms, even if they do not transition to clinical psychosis, a study shows. [More]
Early intervention benefits may not stay the course in psychosis

Early intervention benefits may not stay the course in psychosis

Most of the benefits of a specialised early intervention for psychosis have disappeared by 8 years after its completion, shows follow-up of the OPUS trial. [More]
Study shows how mentally ill women in India go through a vicious cycle

Study shows how mentally ill women in India go through a vicious cycle

An award-winning study by a Loyola University Chicago Stritch School of Medicine researcher has documented how homeless, mentally ill women in India face a vicious cycle [More]
Successful antipsychotic treatment may alter striatal connectivity

Successful antipsychotic treatment may alter striatal connectivity

Connectivity within the striatum changes as psychotic symptoms improve in patients treated with second-generation antipsychotics, a study shows. [More]

Omega-3 benefits may be sustained in early psychosis

The positive effects of omega-3 supplementation seen in patients at high risk of psychosis in a previous randomised, controlled trial may be sustained, the investigators reported at the International Early Psychosis Conference in Tokyo, Japan. [More]
Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen Research & Development, LLC today announced the submission of a New Drug Application (NDA) for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration. The NDA seeks approval for the medication as a treatment for schizophrenia in adults. [More]
Suicidal ideation link to suicide strong in schizophrenia spectrum disorders

Suicidal ideation link to suicide strong in schizophrenia spectrum disorders

The association between suicidal ideation and later suicide is much stronger in patients with schizophrenia spectrum psychosis than in those with mood disorders, show results of a systematic meta-analysis. [More]

Cue processing altered in siblings of schizophrenia patients

The siblings of patients with schizophrenia have altered activity in the ventral striatum during reward anticipation and receipt, a study shows. [More]
ISBD Task Force examines suicide predictors

ISBD Task Force examines suicide predictors

The International Society for Bipolar Disorders Task Force on Suicide has published a meta-analysis of predictors of suicide attempts and deaths. [More]
Genetics underpin bullying victimisation influence on paranoia

Genetics underpin bullying victimisation influence on paranoia

Bullying victimisation in childhood may indicate genetic risk for later psychosis, rather than being an environmental trigger, say UK researchers. [More]
Aspirin can improve efficacy of schizophrenia treatments

Aspirin can improve efficacy of schizophrenia treatments

A new study shows that some anti-inflammatory medicines, such as aspirin, estrogen, and Fluimucil, can improve the efficacy of existing schizophrenia treatments. This work is being presented at the European College of Neuropsychopharmacology conference in Berlin. [More]