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UC Riverside researchers explore effects of early-life exercise

UC Riverside researchers explore effects of early-life exercise

More than one in three adults in the United States is considered to be obese. What impact can exercise done early in life have on the propensity for exercising during the adult years? A team of researchers at the University of California, Riverside did experiments on mice in the lab to find out. Specifically, they evaluated the effects of early exercise on adult physical activity, body mass, food consumption and circulating leptin levels. [More]
Early menstrual cycle could play role in development of ER-negative breast cancer among African-American women

Early menstrual cycle could play role in development of ER-negative breast cancer among African-American women

Early age at menarche, or first menstrual cycle, could play a role in the disproportionate incidence of estrogen receptor (ER)-negative breast cancers diagnosed among African-American women, according to a study published in the Journal of the National Cancer Institute. [More]
Researchers find persistent gender bias in provision of growth hormone treatment for idiopathic short stature

Researchers find persistent gender bias in provision of growth hormone treatment for idiopathic short stature

Short boys are three times more likely than short girls to receive recombinant human growth hormone treatment for idiopathic short stature (ISS), even though in a general pediatric population, equal proportions of both genders fall under the height threshold designating ISS. Researchers who analyzed records of over 283,000 U.S. children and adolescents found a clear-cut and persistent gender bias in the provision of treatment. [More]
Medical experts call for accurate, standardized estrogen testing methods

Medical experts call for accurate, standardized estrogen testing methods

Unreliable estrogen measurements have had a negative impact on the treatment of and research into many hormone-related cancers and chronic conditions. To improve patient care, a panel of medical experts has called for accurate, standardized estrogen testing methods in a statement published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
GnRH infusion recommended for adolescent hypogonadotropic hypogonadodism

GnRH infusion recommended for adolescent hypogonadotropic hypogonadodism

Pulsatile gonadotropin-releasing hormone may be more effective than human chorionic gonadotropin for the treatment of peripubescent boys with hypogonadotropic hypogonadodism, say Chinese researchers. [More]
Puberty timing complicates adiposity measurements

Puberty timing complicates adiposity measurements

Research suggests that the timing of puberty affects the accuracy and interpretation of body mass index z-scores for judging adiposity in both girls and boys. [More]
Lafora rare disease could be aggravated by oxidative stress

Lafora rare disease could be aggravated by oxidative stress

Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and puberty and occurs as a consequence of defects in glycogen metabolism and in the cellular mechanisms that are responsible for its disposal. Researchers at the University of Valencia have led a study in which they propose that Lafora rare disease could be aggravated by oxidative stress. [More]
Study finds similarity in clinical progression between human patients and Huntington's disease monkeys

Study finds similarity in clinical progression between human patients and Huntington's disease monkeys

Transgenic Huntington's disease monkeys show similarity to humans with Huntington's in their progressive neurodegeneration and decline of motor control, scientists from Yerkes National Primate Research Center, Emory University, report. [More]
DNMT1 gene essential to maintain breast and cancer stem cells

DNMT1 gene essential to maintain breast and cancer stem cells

The gene and hormone soup that enables women to breastfeed their newborns also can be a recipe for breast cancer, particularly when the first pregnancy is after age 30. [More]
Study: Women hospitalized for asthma treatment more than men

Study: Women hospitalized for asthma treatment more than men

While it may be a stereotype, it's also true that women seek medical care more frequently than men do. And a recent study shows that women with acute asthma who are treated in the emergency department (ED) are 60 percent more likely than men treated in the ED to need hospitalization. [More]
Long-term histrelin implant shows promise for central precocious puberty

Long-term histrelin implant shows promise for central precocious puberty

Long-term subcutaneous histrelin implant therapy is a viable option for patients with central precocious puberty who require continuous gonadotropin-releasing hormone analogue therapy, say researchers. [More]
Groundbreaking study looks at how puberty affects voice changes in male singers

Groundbreaking study looks at how puberty affects voice changes in male singers

The first round of tests have been completed for members of the Cincinnati Boychoir who are part of a joint study with Cincinnati Children's Hospital Medical Center to look at the changing voices of male singers. [More]
Scientists find link between higher muscle mass and healthier bone development in children

Scientists find link between higher muscle mass and healthier bone development in children

Scientists at the University of Southampton have shown that higher muscle mass is strongly linked with healthier bone development in children. [More]
Researchers find Fountain of Youth while conducting breast cancer research

Researchers find Fountain of Youth while conducting breast cancer research

The Fountain of Youth has been discovered and it's not in Florida as Ponce de Leon claimed. Instead, it was found in the mammary glands of genetically modified mice. [More]
Idiopathic central precocious puberty on the rise in boys

Idiopathic central precocious puberty on the rise in boys

About three-quarters of cases of central precocious puberty in boys have no identifiable cause, say researchers. [More]
Australian researchers find gene that drives aggressive form of triple-negative breast cancer

Australian researchers find gene that drives aggressive form of triple-negative breast cancer

Australian researchers have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad. [More]
New targeted therapy promises to reduce frequency and intensity of breakouts

New targeted therapy promises to reduce frequency and intensity of breakouts

Acne, a scourge of adolescence, may be about to meet its ultra high-tech match. By using a combination of ultrasound, gold-covered particles and lasers, researchers from UC Santa Barbara and the private medical device company Sebacia have developed a targeted therapy that could potentially lessen the frequency and intensity of breakouts, relieving acne sufferers the discomfort and stress of dealing with severe and recurring pimples. [More]
GH response poor in SGA children with good spontaneous catch-up growth

GH response poor in SGA children with good spontaneous catch-up growth

Spontaneous catch-up growth after birth in short children who were born small for gestational age is a negative predictor of their long-term response to growth hormone treatment, say researchers. [More]
Blunted cortisol response common in non-classic CAH

Blunted cortisol response common in non-classic CAH

Nearly two-thirds of children with non-classic congenital adrenal hyperplasia have an inadequate cortisol response, report researchers. [More]
Nomogram aids management of boys with constitutional delay in growth and puberty

Nomogram aids management of boys with constitutional delay in growth and puberty

A puberty nomogram is better than the classical criteria for identifying boys with constitutional delay in growth and puberty, report researchers. [More]
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