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Brain imaging could assist bipolar depression diagnosis

Brain imaging could assist bipolar depression diagnosis

Researchers have identified structural brain differences that could help to distinguish patients with unipolar and bipolar depression. [More]
Subcortical brain regions play key role in memorization process during sleep

Subcortical brain regions play key role in memorization process during sleep

According to researchers at the University of Montreal, the regions of the brain below the cortex play an important role as we train our bodies' movements and, critically, they interact more effectively after a night of sleep. [More]
In vivo dopaminergic imaging strongly correlates with brain pathology

In vivo dopaminergic imaging strongly correlates with brain pathology

Striatal dopamine transporter binding, assessed using single-photon emission computed tomography, is strongly correlated with substantia nigra cell counts assessed at postmortem, say the authors of a study. [More]
Imaging biomarker proposed for Parkinson’s disease

Imaging biomarker proposed for Parkinson’s disease

Reduced off-medication connectivity in the basal ganglia network separates patients with early Parkinson’s disease from healthy controls with high accuracy, preliminary findings suggest. [More]
VLSM provides more accurate prognosis of motor recovery from chronic stroke

VLSM provides more accurate prognosis of motor recovery from chronic stroke

Many studies have examined motor impairments using voxel-based lesion symptom mapping (VLSM), but few are reported regarding the corresponding relationship between cerebral cortex injury and lower limb motor impairment analyzed using this technique. [More]
Dopamine transporter availability predicts ICDs

Dopamine transporter availability predicts ICDs

Reduced striatal dopamine transporter availability is already present in patients with Parkinson’s disease who go on to develop impulse control disorders, a study shows. [More]
Scan may rule out Parkinson’s disease

Scan may rule out Parkinson’s disease

Patients with clinical symptoms of early Parkinson’s disease but no evidence of dopaminergic deficit on brain imaging are unlikely to have the condition, say the PRECEPT Study investigators. [More]
Presynaptic dopaminergic lesion predicts drug-induced dyskinesia

Presynaptic dopaminergic lesion predicts drug-induced dyskinesia

Research suggests that the extent of presynaptic dopaminergic denervation before starting therapy may predict which patients with Parkinson’s disease will later develop levodopa-induced dyskinesia. [More]
Researchers investigate sex differences in brain structure

Researchers investigate sex differences in brain structure

Reviewing over 20 years of neuroscience research into sex differences in brain structure, a Cambridge University team has conducted the first meta-analysis of the evidence, published this week in the prestigious journal Neuroscience and Biobehavioral Reviews. [More]
Study: Depression in Parkinson's patients may reflect impaired striatal dopamine function

Study: Depression in Parkinson's patients may reflect impaired striatal dopamine function

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease (PD) exhibit mild to moderate depression, which is often underdiagnosed. [More]
Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease exhibit mild to moderate depression, which is often underdiagnosed. It is unclear whether depression results from having a debilitating disease or reflects a parallel abnormal change in the brain caused by PD pathophysiology. [More]
‘Risk circuits’ for schizophrenia refined

‘Risk circuits’ for schizophrenia refined

A study sheds further light on the brain circuits that may underlie risk for schizophrenia. [More]
Neuroscientists honored for research into brain's reward and decision-making systems

Neuroscientists honored for research into brain's reward and decision-making systems

Maximum reward, minimum punishment: these are the maxims humans and animals often apply when making decisions. A network of nerve cells in the brain conveys gratification. [More]

Study suggests that human brains are hardwired to empathize with friends, spouses

Perhaps one of the most defining features of humanity is our capacity for empathy - the ability to put ourselves in others' shoes. A new University of Virginia study strongly suggests that we are hardwired to empathize because we closely associate people who are close to us - friends, spouses, lovers - with our very selves. [More]
Identifying bipolarity through MRI's proves successful in initial results

Identifying bipolarity through MRI's proves successful in initial results

​What are some of the most troubling numbers in mental health? Six to 10 -- the number of years it can take to properly diagnose a mental health condition. Dr. Elizabeth Osuch, a Researcher at Lawson Health Research Institute and a Psychiatrist at London Health Sciences Centre and the Department of Psychiatry at Western University, is helping to end misdiagnosis by looking for a 'biomarker' in the brain that will help diagnose and treat two commonly misdiagnosed disorders. [More]
Researchers identify structural anomalies that may increase risk of ADHD in premature newborns

Researchers identify structural anomalies that may increase risk of ADHD in premature newborns

In the first study of its kind, Natasha Leporé, PhD, and colleagues have pinpointed structural anomalies in the developing brain that may increase the risk of cognitive disabilities, such as frontal executive dysfunction and attention deficit hyperactivity disorder, in premature newborns. [More]
Researchers successfully test new anti-cocaine vaccine in primates

Researchers successfully test new anti-cocaine vaccine in primates

Researchers at Weill Cornell Medical College have successfully tested their novel anti-cocaine vaccine in primates, bringing them closer to launching human clinical trials. [More]
TRACK-HD study: A set of tests could help identify progression of Huntington's disease

TRACK-HD study: A set of tests could help identify progression of Huntington's disease

Scientists have identified a set of tests that could help identify whether and how Huntington's disease is progressing in groups of people who are not yet showing symptoms. [More]
Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

Ceregene, Inc. today announced the top-line data from its double-blind, randomized, controlled Phase 2b clinical study of CERE-120 (AAV-neurturin), a gene therapy product designed to deliver the neurotrophic factor neurturin, for Parkinson's disease. [More]
Neurophysiologic mechanisms of deep-brain stimulation unveiled

Neurophysiologic mechanisms of deep-brain stimulation unveiled

The beneficial effects of subthalamic nucleus stimulation in patients with Parkinson’s disease are partly down to compensatory activation of nonmotor dopamine pathways during exercise, research suggests. [More]