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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.
Next generation sequencing applications automated through partnership between Beckman Coulter Life Sciences and New England Biolabs

Next generation sequencing applications automated through partnership between Beckman Coulter Life Sciences and New England Biolabs

Beckman Coulter Life Sciences, through a partnership with New England Biolabs®, Inc. (NEB®), offers automated methods to improve processes and throughput in next generation sequencing (NGS) sample preparation. Under the agreement, Beckman Coulter will use its extensive experience in automated NGS sample prep to develop, distribute and support automation for NEB’s NEBNext® sample preparation reagent kits. NEB will provide technical expertise on the reagents, chemistry and protocols. [More]
New study reveals how cancer becomes drug resistant over time

New study reveals how cancer becomes drug resistant over time

Like a colony of bacteria or species of animals, cancer cells within a tumor must evolve to survive. A dose of chemotherapy may kill hundreds of thousands of cancer cells, for example, but a single cell with a unique mutation can survive and quickly generate a new batch of drug-resistant cells, making cancer hard to combat. [More]
Identifying infections rapidly: an interview with Dr. David J. Ecker

Identifying infections rapidly: an interview with Dr. David J. Ecker

Current methods for diagnosing infectious diseases are based on the 150-year-old culture method, where physicians collect a sample of a patient’s tissue, such as blood, mucus or urine, and transfer it onto media bottle to allow the pathogens to grow. [More]
MMP-3 disrupts brain/spinal cord barrier, promotes hemorrhage

MMP-3 disrupts brain/spinal cord barrier, promotes hemorrhage

Traumatic spinal cord injury (SCI) is a devastating condition with few treatment options. Studies show that damage to the barrier separating blood from the spinal cord can contribute to the neurologic deficits that arise secondary to the initial trauma. Through a series of sophisticated experiments, researchers reporting in The American Journal of Pathology suggest that matrix metalloproteinase-3 (MMP-3) plays a pivotal role in disruption of the brain/spinal cord barrier (BSCB), cell death, and functional deficits after SCI. [More]
Statistical analysis shows stage of breast cancer predicts treatment choice

Statistical analysis shows stage of breast cancer predicts treatment choice

Why did 43 percent of South Dakota women diagnosed with early-stage breast cancer surveyed choose mastectomy rather than lumpectomy? [More]
Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

An international group of scientists led by Gang Han, PhD, at the University of Massachusetts Medical School, has combined a new type of nanoparticle with an FDA-approved photodynamic therapy to effectively kill deep-set cancer cells in vivo with minimal damage to surrounding tissue and fewer side effects than chemotherapy. This promising new treatment strategy could expand the current use of photodynamic therapies to access deep-set cancer tumors. [More]
MU research finds that neurons actively 'fine tune' for electrical imbalances at genetic level

MU research finds that neurons actively 'fine tune' for electrical imbalances at genetic level

Neurons are electrically charged cells, located in the nervous system, that interpret and transmit information using electrical and chemical signals. Now, researchers at the University of Missouri have determined that individual neurons can react differently to electrical signals at the molecular level and in different ways—even among neurons of the same type. [More]
UMMS, UMMSM researchers identify key genetic pathway underlying bipolar disorder

UMMS, UMMSM researchers identify key genetic pathway underlying bipolar disorder

A team of scientists led by researchers at the University of Massachusetts Medical School and the University of Miami Miller School of Medicine have identified what is likely a key genetic pathway underlying bipolar (manic depressive) disorder, a breakthrough that could lead to better drugs for treating bipolar affective disorder, as well as depression and other related mood disorders. [More]
Research finding offers new insights into the cause of glioblastoma

Research finding offers new insights into the cause of glioblastoma

Researchers at the University of California, San Diego School of Medicine have identified a new fusion protein found in approximately 15 percent of secondary glioblastomas or brain tumors. The finding offers new insights into the cause of this cancer and provides a therapeutic target for personalized oncologic care. [More]
Four UCLA researchers receive NIH Director's New Innovator Award

Four UCLA researchers receive NIH Director's New Innovator Award

Four scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a National Institutes of Health Director's New Innovator Award that will forward revolutionary stem cell and neuro-science in medicine. [More]
RNA molecules in tissue, urine samples can detect prostate cancer

RNA molecules in tissue, urine samples can detect prostate cancer

Researchers at Sanford-Burnham Medical Research Institute have identified a set of RNA molecules that are detectable in tissue samples and urine of prostate cancer patients but not in normal healthy individuals. [More]
Researchers discover mitochondrial and nuclear tRNA-lookalikes in human genome

Researchers discover mitochondrial and nuclear tRNA-lookalikes in human genome

Transfer RNAs (tRNAs) are ancient workhorse molecules and part of the cellular process that creates the proteins, critical building blocks of life that keep a cell running smoothly. [More]
Researchers use computer based predictions to combat AIDS

Researchers use computer based predictions to combat AIDS

The battle against AIDS cannot be won in the laboratory alone. To fight the potentially deadly virus that 34 million people are suffering from we need help from computers. [More]
Tel Aviv University researcher advances novel strategy to fight cancer by shoring up the immune system

Tel Aviv University researcher advances novel strategy to fight cancer by shoring up the immune system

Two years ago, Prof. Eshel Ben-Jacob of Tel Aviv University's School of Physics and Astronomy and Rice University's Center for Theoretical Biological Physics made the startling discovery that cancer, like an enemy hacker in cyberspace, targets the body's communication network to inflict widespread damage on the entire system. [More]
New England Biolabs inks deal to supply critical reagents to TriLink BioTechnologies

New England Biolabs inks deal to supply critical reagents to TriLink BioTechnologies

New England Biolabs, Inc. (NEB®) has strengthened its position as a key supplier to the fast-growing RNA synthesis market by signing an agreement to supply critical reagents to TriLink BioTechnologies, Inc., a leading manufacturer of mRNA and long RNA for research, diagnostic and therapeutic applications. [More]
Avidity NanoMedicines closes $6M convertible note financing, expands investor syndicate

Avidity NanoMedicines closes $6M convertible note financing, expands investor syndicate

Avidity NanoMedicines today announced that it has expanded its investor syndicate through the closing of a $6 million convertible note financing co-led by Fidelity Biosciences and TPG Biotech. [More]
New method for extracting potential bone-producing cells from human fat

New method for extracting potential bone-producing cells from human fat

Within our fat lives a variety of cells with the potential to become bone, cartilage, or more fat if properly prompted. This makes adipose tissue, in theory, a readily available reservoir for regenerative therapies such as bone healing if doctors can get enough of those cells and compel them to produce bone. [More]
Ganymed, BioNTech AG open new headquarters and research facility in Germany

Ganymed, BioNTech AG open new headquarters and research facility in Germany

BioNTech AG and Ganymed Pharmaceuticals AG, two premier German biotechology companies, announced today the joint- opening of a new approx. 10,000 square-meters (108,000 square-feet) headquarters and research facility. [More]
Researchers create new Cas9 animal model for in vivo genome editing experiments

Researchers create new Cas9 animal model for in vivo genome editing experiments

Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments. [More]
Cedars-Sinai to participate in a consortium studying motor neuron disorders

Cedars-Sinai to participate in a consortium studying motor neuron disorders

Investigators at the Cedars-Sinai Board of Governors Regenerative Medicine Institute have received a grant from the National Institutes of Health to participate in a consortium taking the study of motor neuron disorders - such as Lou Gehrig's disease and spinal muscular atrophy - to a new, comprehensive perspective. [More]