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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.
MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment. [More]
New research exposes cellular responses linked to bird flu vaccine

New research exposes cellular responses linked to bird flu vaccine

New research from Vanderbilt eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu. [More]
Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. [More]
CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. [More]
UC biologists use frog models to study how early stressors may play role in onset of adult diseases

UC biologists use frog models to study how early stressors may play role in onset of adult diseases

UC biologists have turned to amphibian sources -- specifically frogs and tadpoles -- to help shed light on how early stressors in the womb and shortly after birth may play a part in the onset of adult diseases such as diabetes and cardiovascular disease. [More]
Scientists identify 'molecular barcode' in blood samples that can predict survival of Ebola patients

Scientists identify 'molecular barcode' in blood samples that can predict survival of Ebola patients

Scientists have identified a 'molecular barcode' in the blood of patients with Ebola virus disease that can predict whether they are likely to survive or die from the viral infection. [More]
Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells. [More]
Researchers identify brain cell types from cell culture of adult human neurons

Researchers identify brain cell types from cell culture of adult human neurons

Studying brain disorders in people and developing drugs to treat them has been slowed by the inability to investigate single living cells from adult patients [More]
Metabolomics and NMR

Metabolomics and NMR

Bruker has been involved in the Phenome Center network since its beginning. Several years ago, the whole visionary concept of a global phenome network was actually born with Professor Jeremy Nicholson and Bruker BioSpin has been part of it since the early stages. [More]
MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy. [More]
Penn Vet researchers identify potential target to fight against Ebola

Penn Vet researchers identify potential target to fight against Ebola

Viruses and their hosts are in a eternal game of one-upmanship. If a host cell evolves a way to stop a virus from spreading, the virus will look for a new path. And so on and so forth. [More]
Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

Tokyo Institute of Technology research: Gravitational biology: Real time imaging and transcriptome analysis of medaka aboard space station [More]
Surveillance machinery in cells recognizes and destroys defective genetic material, research shows

Surveillance machinery in cells recognizes and destroys defective genetic material, research shows

New research out of Case Western Reserve University School of Medicine describes a mechanism by which an essential quality control system in cells identifies and destroys faulty genetic material. The findings were published online December 23 in Nature Communications. [More]
Retroviruses almost several hundred million years older than previously thought

Retroviruses almost several hundred million years older than previously thought

Retroviruses - the family of viruses that includes HIV - are almost half a billion years old, according to new research by scientists at Oxford University. [More]
Researchers find high-resolution structure of immature Zika virus

Researchers find high-resolution structure of immature Zika virus

Researchers at Purdue University have determined the high-resolution structure of immature Zika virus, a step toward better understanding how the virus infects host cells and spreads. [More]
Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Johns Hopkins researchers along with academic and drug industry investigators say they have identified a new biological target for treating spinal muscular atrophy. [More]
Houston Methodist researchers advance potential treatment for metaplastic breast cancer

Houston Methodist researchers advance potential treatment for metaplastic breast cancer

Houston Methodist Hospital researchers have advanced a potential treatment for metaplastic breast cancer--the most aggressive subtype of triple negative breast cancer, into patients in just under four years. [More]
TSRI scientists develop new tool to uncover molecular details of protein structure

TSRI scientists develop new tool to uncover molecular details of protein structure

Scientists on the Florida campus of The Scripps Research Institute have developed a new tool for studying the molecular details of protein structure. [More]
How does the brain control appetite?

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body. [More]
Researchers identify possible treatment targets for myelodysplasia syndromes

Researchers identify possible treatment targets for myelodysplasia syndromes

Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) - a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells. [More]
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