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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.
Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72. [More]
Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

An international collaboration of researchers are advancing precision medicine to men with advanced prostate cancer. [More]
Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer. [More]
Johns Hopkins researchers identify new therapy to treat lung cancer

Johns Hopkins researchers identify new therapy to treat lung cancer

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team. [More]
MO BIO announces launch of PowerMag DNA Clean-Up Kit

MO BIO announces launch of PowerMag DNA Clean-Up Kit

MO BIO Laboratories, Inc., the leader in soil, environmental, plant and microbial nucleic acid purification, announces the launch of the PowerMag DNA Clean-Up Kit, for automated, hands-free clean-up of DNA samples that require a secondary purification for removal of PCR inhibitors. This kit features MO BIO's novel ClearMag magnetic bead technology. [More]
MD Anderson researchers find significant clinical variations among liver cancer patients

MD Anderson researchers find significant clinical variations among liver cancer patients

Significant clinical variations exist among patients with the most common type of liver cancer called hepatocellular carcinoma (HCC), depending on the viral cause of the disease -hepatitis B virus (HBV) or hepatitis C virus (HCV). These differences suggest that hepatitis status should be considered when developing treatment plans for newly diagnosed patients, according to researchers at The University of Texas MD Anderson Cancer Center. [More]
Long, non-coding RNAs play a role in heart attacks, strokes and cancer

Long, non-coding RNAs play a role in heart attacks, strokes and cancer

About 70 percent of our genes provide the blueprint for biomolecules whose function is only now being discovered - non-coding RNAs. Instead of being translated into proteins, they seem to perform steering functions in the body. [More]
UCL-led team develops new technique to find resistant TB faster

UCL-led team develops new technique to find resistant TB faster

The time needed to genetically sequence the bacteria causing tuberculosis (Mtb) from patient samples has been reduced from weeks to days using a new technique developed by a UCL-led team. This could help health service providers to better treat disease, control transmission of this infection, and monitor outbreaks. [More]
Soligenix, Emergent BioSolutions sign development agreement

Soligenix, Emergent BioSolutions sign development agreement

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today that it has initiated a development agreement with Emergent BioSolutions to implement a commercially viable, scalable production technology for the RiVax drug substance protein antigen. [More]
Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Researchers at Case Western Reserve University combined finely crafted nanoparticles with one of nature's potent disrupters to prevent the spread of triple-negative breast cancer in mouse models. [More]
Research paves way for development of individualized immunotherapy for treating cancer

Research paves way for development of individualized immunotherapy for treating cancer

Mainz-based researchers have made significant advances with regard to the development of individualized immunotherapy strategies for treating cancer. They have managed to identify the relevant genetic changes or mutations associated with various types of cancer and have determined their individual blueprints. [More]
New study discovers master switch that drives heart cell maturation process

New study discovers master switch that drives heart cell maturation process

A molecular switch that seems to be essential for embryonic heart cells to grow into more mature, adult-like heart cells has been discovered. [More]
MD Anderson researchers discover link between telomere degeneration and MDS

MD Anderson researchers discover link between telomere degeneration and MDS

A study revealing fresh insight about chromosome "tails" called telomeres may provide scientists with a new way to look at developing treatments or even preventing a group of blood cell disorders known as myelodysplastic syndromes (MDS). [More]
Study sheds light on developing more targeted therapies against medulloblastoma

Study sheds light on developing more targeted therapies against medulloblastoma

St. Jude Children's Research Hospital scientists have gained ground toward developing more targeted therapies for the most common childhood brain tumor. [More]
GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease. [More]
Discovery may have opened up new frontier in fight against breast cancer

Discovery may have opened up new frontier in fight against breast cancer

For years, scientists have been puzzled by the presence of short stretches of genetic material floating inside a variety of cells, ranging from bacteria to mammals, including humans. These fragments are pieces of the genetic instructions cells use to make proteins, but are too short a length to serve their usual purpose. [More]
Cleaver Scientific launch safe series DNA electrophoresis products

Cleaver Scientific launch safe series DNA electrophoresis products

The 'Safe' Series of products from Cleaver Scientific have been designed to make DNA electrophoresis procedures safer, more convenient and more economical to run. [More]
Scientists uncover new pharmaceutical strategy for treating melanoma

Scientists uncover new pharmaceutical strategy for treating melanoma

Scientists looking to better understand the mechanisms behind the origin and spread of melanoma tumors have uncovered a possible role for a decades-old antibacterial agent in treating these aggressive and increasingly common cancers. [More]
ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

ViiV Healthcare today announced the start of a Phase III clinical trial programme to evaluate the safety and efficacy of dolutegravir (Tivicay) and rilpivirine (Edurant) as maintenance therapy for adult patients with HIV. [More]
NEB announces issuance of US patent for RNA-seq technology

NEB announces issuance of US patent for RNA-seq technology

New England Biolabs, Inc. announces the issuance of United States Patent Number 8,999,677, which describes a novel method for retaining valuable strand-specific information contained within RNA transcripts. [More]
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