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New gene therapy helps stroke patients develop new neurons

Ischemic stroke is a condition in which parts of the brain lose their blood supply, causing nerve damage. Once brain tissue suffers irreparable harm, the patient will experience irreversible disability or death, depending on the extent of neuronal loss.

12 Sep 2019

Inflammation in the lungs triggers silent mutation to cause pulmonary hypertension

Researchers at the Stanford University School of Medicine have found that inflammation in the lungs of rats, triggered by something as simple as the flu, may wake up a silent genetic defect that causes sudden onset cases of pulmonary hypertension, a deadly form of high blood pressure in the lungs.

29 Aug 2019

Traumatic brain injuries could be healed using peptide hydrogels

Traumatic brain injury (TBI) –– defined as a bump, blow or jolt to the head that disrupts normal brain function –– sent 2.5 million people in the U.S. to the emergency room in 2014, according to statistics from the U.S. Centers for Disease Control and Prevention.

27 Aug 2019

Polycystic kidney disease may be preventable

Kidney failure is a lifelong burden in hundreds of thousands of people who need to be treated either by dialysis or a kidney transplant. Both procedures significantly increase the cost of healthcare and reduce the quality of life.

26 Aug 2019

Healthy blood vessels could help stave off cognitive decline

High blood pressure may affect conditions such as Alzheimer’s disease by interfering with the brain’s waste management system, according to new research in rats published in JNeurosci. Maintaining blood vessel health could therefore help stave off cognitive decline.

From Society for Neuroscience 19 Jun 2019

Inhaling irritant that mimics air pollution changes defensive heart-lung reflex for hypertension

Air pollution significantly increases the risk for premature deaths, particularly in people with underlying cardiovascular disease, clinical and epidemiological studies have determined.

19 Jun 2019

Researchers develop promising reconstruction method based on 3D-printed esophageal grafts

The loss of complete segments of the esophagus often results from treatments for esophageal cancer or congenital abnormalities, and current methods to re-establish continuity are inadequate.

18 Jun 2019

Ultra-Small Microelectrode Biosensors for Brain Injury Analysis

An interview with Stéphane Marinesco, discussing the development of ultra-small microelectrode biosensors for the analysis of traumatic brain injuries.

From Pittcon 14 Jun 2019

Viral infection in utero associated with behavioral abnormalities in offspring

Male and female rats whose mother experienced a simulated viral infection during pregnancy behave abnormally, consistent with behavioural alterations in autism or schizophrenia, research by the University of Saskatchewan shows.

2 May 2019

Exploring novel strategies to heal damage after a heart attack

For people who survive a heart attack, the days immediately following the event are critical for their longevity and long-term healing of the heart's tissue.

24 Apr 2019

Oxytocin blocks excess drinking in alcohol-dependent rats

The neuropeptide oxytocin blocks enhanced drinking in alcohol-dependent rats, according to a study published April 16 in the open-access journal PLOS Biology led by Drs. Tunstall, Koob and Vendruscolo of the National Institutes of Health, and Drs. Kirson and Roberto of The Scripps Research Institute.

17 Apr 2019

Coagulation factor VIIa prevents bleeds in hemophilia animal models

Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well.

16 Apr 2019

Study: Pathogenetic downregulation of adenosine linked to restless leg syndrome

Researchers have identified a common mechanism implicating adenosine in the cause of restless leg syndrome symptoms — the periodic limb movements characteristic of RLS and the state of enhanced arousal that both disrupt sleep.

4 Apr 2019

Simplifying Gene Expression Analysis in Neuroscience Research

In this interview, Kevin Gamber introduces the Neuroscience panel of the NanoString service for gene expression analysis from Canopy Biosciences.

From Canopy Biosciences 3 Apr 2019

Piece of puzzle unlocked in what drives alcohol addiction

Researchers at the Scripps Research Institute have made an important discovery that may help to explain the neural mechanism that drives alcohol consumption in cases of addiction.

19 Mar 2019

Scientists identify brain circuit responsible for cocaine-seeking behavior during relapse

Approximately 1.5 million Americans use cocaine in a given year, according to the National Institute on Drug Abuse. Many are repeat users. Unfortunately, there are currently no FDA-approved medicinal treatments for cocaine addiction.

19 Mar 2019

Scientists reverse alcohol-seeking behavior in rats with flip of a switch

Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats--with the flip of a switch.

19 Mar 2019

Menstrual cycle may influence addiction risk in women, suggests study

Menstrual cycle may influence addiction risk in women, according to a new study in Biological Psychiatry by researchers at the National Institute on Drug Abuse and University of Maryland School of Medicine.

5 Mar 2019

Change in genome of Caucasians could explain higher rates of esophageal cancer

A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds.

21 Dec 2018