Reactive Oxygen Species (ROS) News and Research

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Diets high in lutein, zeaxanthin and vitamin E lower risk for cataracts

Women who have higher dietary intake of lutein and zeaxanthin—compounds found in yellow or dark, leafy vegetables—as well as more vitamin E from food and supplements appear to have a lower risk for developing cataracts, according to a report in the January issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

15 Jan 2008

Avoiding sweets may spell a longer life

A new study in the October issue of Cell Metabolism, a publication of Cell Press, reveals that worms live to an older age when they are unable to process the simple sugar glucose.

3 Oct 2007

Daisy compound used to attack cancer stem cells

A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood.

2 Oct 2007

Researchers look at role of oxidative stress in human diseases

Oxidative stress is known to underlie many human diseases including atherosclerosis, Parkinson's disease and Alzheimer's disease.

17 Sep 2007

Proteins Nox1 and Nox2 play important role in amyotrophic lateral sclerosis

University of Iowa researchers investigating the basic biology of cell signaling have made a discovery that may have therapeutic implications for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

13 Sep 2007

Yellow plant pigments may lower risk for age-related eye disease

Consuming higher levels of the yellow plant pigments lutein and zeaxanthin may be associated with a lower risk for age-related macular degeneration, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Sep 2007

Metabolic cell activity directly controls life and death decisions in cells

Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells.

13 Aug 2007

Use of aluminium in sunscreens and sunblocks questioned

Scientists at Keele University in Staffordshire have questioned the safety of aluminium added to sunscreens and sunblocks.

13 Aug 2007

Antioxidant overload

Despite the popular notion that antioxidants, such as vitamins C and E, offer health-promoting benefits by protecting against damaging free radicals, a new study in the August 10 issue of the journal Cell reveals that, in fact, balance is the key.

12 Aug 2007

Air pollution has a role to play in atherosclerosis

Should we be watching our exposure to airborne pollution as well as our cholesterol levels?

26 Jul 2007

Orange juice healthy for diabetics

Orange juice, despite its high caloric load of sugars, appears to be a healthy food for diabetics due to its mother lode of flavonoids, a study by endocrinologists at the University at Buffalo has shown.

18 Jul 2007

Myeloid-derived suppressor cells suppress anti-tumor response to cancer

Scientists at Johns Hopkins and elsewhere say they have mapped out an escape route that cancers use to evade the body's immune system, allowing the disease to spread unchecked.

17 Jul 2007

Potential new treatment pathway for Parkinson's

In the vast majority of Parkinson's disease (PD) patients, the disorder arises not because of a genetic defect, but because some external insult triggers the death of dopamine-producing neurons.

9 Jul 2007

Reactive oxygen species mediate a cellular 'memory' of high glucose stress signaling

Researchers at the University of Warwick’s Warwick Medical School have uncovered a process that locks the body’s metabolism in a diabetic state after only relatively limited exposure to high glucose levels.

29 Jun 2007

Cause of gender differences in high blood pressure and related kidney disease

While men and women both get high blood pressure and related kidney disease, the path to get there is shorter, steeper and just different for men, researchers say.

4 May 2007

Naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells

These findings, which were published online March 20 in the Journal of Biological Chemistry and will be in press on May 4, offer hope for a more selective, less toxic therapy for leukemia.

24 Apr 2007

Researcher looks at health benefits of plant-based phytochemicals

Nutrition: It's not just the four basic food groups any more. Researcher Dr. Susanne Mertens-Talcott of Texas A&M University is looking into how plant-based phytochemicals, including antioxidants and herbal supplements, can be useful in the promotion of health and prevention of chronic diseases.

19 Apr 2007

Antipodean Pharma commences phase 2 trial in hepatitis C

Antipodean Pharmaceuticals has announced it has initiated a Phase 2 clinical trial of its lead compound MitoQ (mitoquinone) to investigate the drug's efficacy to reduce liver damage in patients with raised liver enzymes associated with the Hepatitis C virus (HCV).

5 Feb 2007

FoxOs shown to be potential new targets for cancer drugs

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

29 Jan 2007

Vascular targeted nanoparticles for imaging and treatment of brain tumors

Combining two promising approaches to diagnosing and treating cancer, a multidisciplinary research team at the University of Michigan has created a targeted multifunctional polymer nanoparticle that successfully images and kills brain tumors in laboratory animals.

4 Dec 2006