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African American men with prostate cancer have significantly lower PSA density than Caucasian men

A new study published in The Journal of Urology revealed that African American men with Gleason score 3+3=6 prostate cancer (PCa) produce less prostate specific antigen (PSA) and have significantly lower PSA density (PSAD) than Caucasian men. These findings could have important implications when selecting patients for inclusion in active PCa surveillance programs.

5 Jan 2016

New studies to improve prostate cancer detection to be presented at AUA annual meeting

Five new studies evaluating the use of imaging and urine-based biomarkers as ways to improve prostate cancer detection will be presented during the 110th Annual Scientific Meeting of the American Urological Association (AUA).

18 May 2015

Study: Targeted biopsy technique better than standard biopsy at detecting high-risk prostate cancer

Among men undergoing biopsy for suspected prostate cancer, targeted magnetic resonance/ultrasound fusion biopsy, compared with a standard biopsy technique, was associated with increased detection of high-risk prostate cancer and decreased detection of low-risk prostate cancer, according to a study in the January 27 issue of JAMA.

28 Jan 2015

BRCA2 mutations herald poor prognosis in screen-detected prostate cancer

Among men with prostate cancer detected on screening, survival among those with a mutation in the BRCA2 gene is much poorer than in those without such a mutation, researchers report.

18 Aug 2014

Beckman announces national availability of Prostate Health Index

Beckman Coulter Diagnostics, a global leader in prostate cancer diagnostics, announces national availability of the Prostate Health Index (phi)*, a simple, non‐invasive blood test that is three times more specific in detecting prostate cancer1 than PSA (prostate‐specific antigen).

22 Jul 2014

Six essential screening tests all men should receive during lifetime

When it's comes men and health, the numbers don't stack up. Compared to women, men are 24 percent less likely than women to visit the doctor, according to the U.S. Department of Health & Human Services. Yet, men are 28 percent more likely than women to be hospitalized for congestive heart failure and 32 percent more likely to receive care for complication of diabetes.

17 Jun 2014

Vitamin D deficiency predicts prostate biopsy outcomes

Men with vitamin D deficiency are more likely than men with normal levels to test positive for prostate cancer on biopsy, and to have aggressive disease, US researchers have found.

28 May 2014

Possible link between aggressive prostate cancer and vitamin D deficiency

Vitamin D deficiency was an indicator of aggressive prostate cancer and spread of the disease in European-American and African-American men who underwent their first prostate biopsy because of abnormal prostate-specific antigen (PSA) and/or digital rectal examination (DRE) test results, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

1 May 2014

Noninvasive technique detects prostate cancer using an electronic nose

We may soon be able to make easy and early diagnoses of prostate cancer by smell. Investigators in Finland have established that a novel noninvasive technique can detect prostate cancer using an electronic nose. In a proof of principle study, the eNose successfully discriminated between prostate cancer and benign prostatic hyperplasia (BPH) by "sniffing" urine headspace (the space directly above the urine sample). Results using the eNose are comparable to testing prostate specific antigen (PSA), reports the Journal of Urology.

1 May 2014

Inflammation has ‘etiologic link’ with prostate cancer

Chronic inflammation of prostate tissue is strongly associated with subsequent development of prostate cancer, show results of a US observational study.

28 Apr 2014

Study: Chronic inflammation associated with aggressive prostate cancer

The presence of chronic inflammation in benign prostate tissue was associated with high-grade, or aggressive, prostate cancer, and this association was found even in those with low prostate-specific antigen (PSA) levels, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

18 Apr 2014

Risk-based approach for screening men at increased risk of prostate cancer

The UK needs to invest in testing for those men most at risk of prostate cancer rather than follow a cast-the-net-wide approach targeting the whole population, a leading scientist from The University of Manchester - part of Manchester Cancer Research Centre - has argued at an international conference this week.

From The University of Manchester 10 Mar 2014

African American men have increased risk of prostate cancer

African American men have an increased risk of prostate cancer and are two times more likely than Caucasian American men to die from the disease. Despite recent questions about the overall usefulness of prostate-specific antigen testing to detect prostate cancer, should PSA screening be used to detect early-stage disease to help save lives in this at-risk population? The controversy is explored in a Review article in Journal of Men's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

7 Jan 2014

Bladder involvement can lead to prostate cancer misdiagnosis

Men with lesions in the neck, trigone, or posterior wall of the bladder should be tested for basal prostate cancer as well as bladder cancer to ensure that they are not misdiagnosed, say researchers.

14 Oct 2013

Study evaluates genetic predisposition in BPH patients developing prostate cancer

Patients with benign prostatic hyperplasia carrying prostate cancer a risk alleles are a potential target population for PCa screening and follow-up, according to a study, which was presented yesterday at the 28th Annual EAU Congress in Milan.

19 Mar 2013

Digital rectal exam important for prostate screening, researchers say

The digital rectal exam is an important screening test that can discover prostate cancer that a prostate-specific antigen or PSA test may not, despite the higher sensitivity of the PSA test, according to Penn State College of Medicine researchers.

19 Mar 2013

Cutting down on fried food could lower prostate cancer risk

Men who eat deep-fried food at least once a week may be increasing their risk for developing prostate cancer, show findings from a US study.

4 Feb 2013

Combination of novel drug therapy and PSA test can effectively detect prostate cancer

Researchers have successfully developed and tested a new prostate cancer screening method that uses the combined power of a novel drug therapy and changes in PSA levels over time to identify men with a high PSA who are more likely to have aggressive prostate cancer despite negative biopsies.

12 Aug 2012

Researchers develop and test new prostate cancer screening method

9 Aug 2012

Researchers call for digital rectal exam revival

Rates of digital rectal examination are low in clinical practice and levels of sufficient training in the technique may be in decline, the results of a US study suggest.

8 Aug 2012