Red Blood Cells News and Research

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Penn study on gut cell regeneration reconciles long-standing research controversy

The lining of the intestine regenerates itself every few days as compared to say red blood cells that turn over every four months. The cells that help to absorb food and liquid that humans consume are constantly being produced. The various cell types that do this come from stem cells that reside deep in the inner recesses of the accordion-like folds of the intestines, called villi and crypts.

11 Nov 2011

British researchers discover receptor necessary for malaria parasite to invade red blood cells, offering new vaccine hope

Researchers from the Wellcome Trust Sanger Institute in the U.K. have "made a critical discovery about the way the most deadly species of malaria parasite invades human red blood cells," Reuters reports.

11 Nov 2011

Universally effective malaria vaccine on the horizon

Scientists are excited with a new breakthrough in development of an effective vaccine against malaria. The latest study finds how malaria acts and how the vaccine would be able to protect individuals from malaria.

10 Nov 2011

Study reveals need for defining optimal amount of iron in infant formula

A 10-year follow-up study examining iron-fortified vs. low-iron infant formula suggests that infants with high hemoglobin levels who received iron fortified infant formula have poorer long-term developmental outcomes.

9 Nov 2011

Increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients

A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease.

3 Nov 2011

NIH-funded project to discover biomarkers for type 2 diabetes

Arizona State University will lead a four-year, $5 million expanded initiative sponsored by the National Institutes of Health to discover proteins, or biomarkers, to help predict cardiovascular disease and to assess potential new treatments in people with type 2 diabetes.

2 Nov 2011

Light-cell interaction and Born approximation rule can help detect misshapen red blood cells

Misshapen red blood cells are a sign of serious illnesses, such as malaria and sickle cell anemia. Until recently, the only way to assess whether a person's RBCs were the correct shape was to look at them individually under a microscope - a time-consuming process for pathologists.

1 Nov 2011

First results from phase 3 malaria vaccine candidate trial

First results from a large-scale Phase III trial of RTS,S, published online today in the New England Journal of Medicine (NEJM), show the malaria vaccine candidate to provide young African children with significant protection against clinical and severe malaria with an acceptable safety and tolerability profile. The results were announced today at the Malaria Forum hosted by the Bill & Melinda Gates Foundation in Seattle, Washington.

18 Oct 2011

BCL11A protein might serve as potential target for sickle cell disease

Flipping a single molecular switch can reverse illness in a model of sickle cell disease, according to a study by researchers at Children's Hospital Boston and Dana-Farber Cancer Institute. When turned off, the switch, a protein called BCL11A, allows the body to manufacture red blood cells with an alternate form of hemoglobin unaffected by the mutation that causes the disease.

14 Oct 2011

Entirely new platform to assist in developing antimalarial drugs

Malaria has been one of the world's biggest killers for as long as records have been kept. With resistance to existing antimalarial drugs on the rise, there is a renewed push to find different ways to fight it. Two University of Houston (UH) engineers have stepped up to the plate to answer the call.

14 Oct 2011

Potential new protein target for sickle cell disease

National Institutes of Health-funded scientists have corrected sickle cell disease in adult laboratory mice by activating production of a special blood component normally produced before, but not after, birth.

14 Oct 2011

Hospitalized patients with anemia may not always benefit from transfusion

University of Kentucky researchers, including lead author Samy Selim of the Division of Cardiovascular Medicine and the Saha Cardiovascular Research Center, have recently published a paper suggesting that transfusion may not always be the best treatment for hospitalized patients with anemia.

13 Oct 2011

Researchers identify new enzyme function that may protect against anemia

Researchers at St. Michael's Hospital have discovered a new function for an enzyme that may protect against organ injury and death from anemia.

4 Oct 2011

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

Using a patient's own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene.

29 Sep 2011

Researchers validate two parasite enzymes as potential anti-malarial drug targets

Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source.

28 Sep 2011

Close link between SF3B1 mutation and specific feature of myelodysplastic syndromes

Geneticists have discovered that a gene involved in the modification of ribonucleic acid (RNA) is mutated in a significant proportion of people with a collection of blood cancers called myelodysplastic syndromes.

27 Sep 2011

Researchers identify frequent SF3B1 gene mutation in myelodysplasia

A genomic study of chronic blood cancer - a precursor to leukaemia - has discovered gene mutations that could enable diagnosis using only a blood test, avoiding the need for an invasive and painful bone marrow biopsy.

27 Sep 2011

Psychological stress of racial discrimination may contribute to health disparities

The consequences of psychological stress, resulting from racial discrimination, may contribute to racial health disparities in conditions such as cardiovascular disease, diabetes and other age-associated diseases.

15 Sep 2011

First effective blood-stage vaccine against malaria

Scientists have identified the first effective blood-stage malaria vaccine, according to a New England Journal of Medicine study from University of Maryland School of Medicine researchers, in collaboration with the University of Bamako in Mali, West Africa, and other partners.

15 Sep 2011

Acceleron commences ACE-536 Phase 1 clinical trial in anemia

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases today announced that it has initiated a Phase 1 clinical study of ACE-536.

14 Sep 2011

Red Blood Cells News and Research

Penn study on gut cell regeneration reconciles long-standing research controversy

British researchers discover receptor necessary for malaria parasite to invade red blood cells, offering new vaccine hope

Universally effective malaria vaccine on the horizon

Study reveals need for defining optimal amount of iron in infant formula

Increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients

NIH-funded project to discover biomarkers for type 2 diabetes

Light-cell interaction and Born approximation rule can help detect misshapen red blood cells

First results from phase 3 malaria vaccine candidate trial

BCL11A protein might serve as potential target for sickle cell disease

Entirely new platform to assist in developing antimalarial drugs

Potential new protein target for sickle cell disease

Hospitalized patients with anemia may not always benefit from transfusion

Researchers identify new enzyme function that may protect against anemia

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

Researchers validate two parasite enzymes as potential anti-malarial drug targets

Close link between SF3B1 mutation and specific feature of myelodysplastic syndromes

Researchers identify frequent SF3B1 gene mutation in myelodysplasia

Psychological stress of racial discrimination may contribute to health disparities

First effective blood-stage vaccine against malaria

Acceleron commences ACE-536 Phase 1 clinical trial in anemia

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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