Remdesivir News and Research

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What are the predictors of in-hospital mortality in cancer patients with COVID-19?

A new study in PLoS ONE aimed to analyze the variables associated with in-hospital mortality in COVID-19-positive cancer patients who were presented to the ED.

3 Feb 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

The safety and tolerability of Remdesivir in children affected by COVID-19

Researchers reported findings of a multicenter study conducted across ten hospitals in Italy to investigate the safety of RDV in children affected by COVID-19.

2 Feb 2023

Potent small-molecule inhibitors against SARS-CoV, MERS-CoV, and SARS-CoV-2

In a recent study posted to bioRxiv* preprint server, researchers in the United States identified several potent pan-coronavirus (CoV) inhibitors.

23 Jan 2023

What older Americans need to know about taking Paxlovid

A new coronavirus variant is circulating, the most transmissible one yet. Hospitalizations of infected patients are rising. And older adults represent nearly 90% of U.S. deaths from covid-19 in recent months, the largest portion since the start of the pandemic.

18 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

In a recent study posted to the bioRxiv* preprint server, researchers at Emory University used severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Washington (WA.1) and Omicron (BA.1) strains to test for mutations that could result in resistance to the antiviral drug nirmatrelvir.

8 Jan 2023

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Researchers presented the results of a phase III randomized controlled trial of oral SARS-CoV-2 antiviral VV116.

3 Jan 2023

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

Researchers investigated the efficacy of ritonavir and nirmatrelvir combination treatment in reducing the risk of COVID-19 severity outcomes such as hospital admissions and deaths when administered during the initial period of SARS-CoV-2 infections.

16 Dec 2022

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Researchers assessed the impact of bebtelovimab (BEB) monoclonal antibody in the treatment of high-risk SARS-CoV-2 Omicron variant-infected patients.

13 Dec 2022

Is remdesivir treatment associated with reduced risk of inpatient mortality among US patients hospitalized with COVID-19?

Researchers assessed the effect of remdesivir on inpatient COVID-19-associated mortality among individuals hospitalized with SARS-CoV-2 infections in an enormous dataset of US residents beyond clinical trial settings.

6 Dec 2022

Exploring clinical characteristics and outcomes of hospitalized COVID-19 patients

Researchers described the clinical characteristics and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in the Netherlands.

24 Nov 2022

Study aims to develop broad-spectrum antivirals against SARS-CoV-2 via drug repurposing strategies

This study aims to determine which FDA-approved compound(s) can be repurposed as a broad-spectrum antiviral drug(s) against SARS-CoV-2 and variants.

24 Nov 2022

Remdesivir appears to make a big difference in Japanese patients with COVID-19

The COVID-19 pandemic has led to an explosion of clinical research resulting in the development of a variety of vaccines and treatments, although the efficacy of some remains controversial.

22 Nov 2022

Study finds a lower compliance rate with recently released guidelines for COVID-19 care

Uptake of national guidelines for the treatment of children hospitalized with COVID-19 fell well below what would typically be expected, report researchers at the Medical University of South Carolina (MUSC) and elsewhere in Pediatrics.

17 Nov 2022

Among US veterans with COVID-19, few used antivirals or monoclonal antibodies

In a recent study published in the journal JAMA Network, researchers in the United States investigated factors that restricted the use of antivirals directed at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States (US) between January and February 2022.

16 Nov 2022

Exploring antiviral drug combinations for SARS-CoV-2 suppression

Researchers assessed the impact of drug combinations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suppression.

14 Nov 2022

Outcomes from an Australian COVID-19 virtual ward during Omicron wave

In a recent study posted to the medRxiv* preprint server, researchers in Australia characterized hospitalization volumes, patient epidemiological and clinical outcome data of patients admitted to virtual wards during the predominance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) BA.1 sub-VOC and the Omicron BA.2 sub-VOC.

8 Nov 2022

Evaluating dual direct-acting antivirals against persistent COVID-19

Researchers assessed the efficiency of dual direct-acting antivirals in treating persistent coronavirus disease 2019 (COVID-19).

7 Nov 2022

Remdesivir News and Research

What are the predictors of in-hospital mortality in cancer patients with COVID-19?

The relationship between natural plant extracts and SARS-CoV-2

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

The safety and tolerability of Remdesivir in children affected by COVID-19

Potent small-molecule inhibitors against SARS-CoV, MERS-CoV, and SARS-CoV-2

What older Americans need to know about taking Paxlovid

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Is remdesivir treatment associated with reduced risk of inpatient mortality among US patients hospitalized with COVID-19?

Exploring clinical characteristics and outcomes of hospitalized COVID-19 patients

Study aims to develop broad-spectrum antivirals against SARS-CoV-2 via drug repurposing strategies

Remdesivir appears to make a big difference in Japanese patients with COVID-19

Study finds a lower compliance rate with recently released guidelines for COVID-19 care

Among US veterans with COVID-19, few used antivirals or monoclonal antibodies

Exploring antiviral drug combinations for SARS-CoV-2 suppression

Outcomes from an Australian COVID-19 virtual ward during Omicron wave

Evaluating dual direct-acting antivirals against persistent COVID-19

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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