Rett Syndrome News and Research RSS Feed - Rett Syndrome News and Research

Rett syndrome is a neurological and developmental disorder that mostly occurs in females. Infants with Rett syndrome seem to grow and develop normally at first, but then stop developing and even lose skills and abilities. For instance, they stop talking even though they used to say certain words. They lose their ability to walk properly. They stop using their hands to do things and often develop stereotyped hand movements, such as wringing, clapping, or patting their hands. Rett syndrome is considered one of the autism spectrum disorders. Most cases of Rett syndrome are caused by a mutation on the MECP2 gene, which is found on the X chromosome.

New drug for treating Rett syndrome is on the horizon

A powerful new drug which could relieve the symptoms of devastating childhood disease Rett syndrome is on the horizon thanks to a funding injection of -180,000. [More]
Nine fellows selected to receive Dennis Weatherstone Predoctoral Fellowship for next two years

Nine fellows selected to receive Dennis Weatherstone Predoctoral Fellowship for next two years

​Autism Speaks, the world's leading autism science and advocacy organization, today announced the sixth class of The Dennis Weatherstone Predoctoral Fellows funded by the Stavros Niarchos Foundation. [More]

IRSF announces new research grants for translational research program and clinical trials

The International Rett Syndrome Foundation (IRSF) announces today ten (10) new research grants at leading global research institutions; a new Translational Research Program; and additional funding for current human clinical trials. [More]

Researchers receive funding to develop treatments for Rett Syndrome

Researchers from Scotland and the US are taking a step towards reversing the effects of a debilitating genetic disease and bring hope to tens of thousands of sufferers worldwide. [More]
Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

In normal development, all cells turn off genes they don’t need, often by attaching a chemical methyl group to the DNA, a process called methylation. Historically, scientists believed methyl groups could only stick to a particular DNA sequence: a cytosine followed by a guanine, called CpG. But in recent years, they have been found on other sequences, and so-called non-CpG methylation has been found in stem cells, and in neurons in the brain. [More]

Autism Speaks grants $2.7M to develop potential treatments for ASD, increase access to high-quality early intervention

Autism Speaks, the world's leading autism science and advocacy organization, today announced the award of nearly $2.7 million for the funding of 13 new research projects over the next three years. [More]
Four U.S. researchers to receive grants to improve cognition in individuals living with Down syndrome

Four U.S. researchers to receive grants to improve cognition in individuals living with Down syndrome

The Scientific Advisory Board of the Jerome Lejeune Foundation USA has recommended 4 U.S. researchers to receive grants from the Foundation for its second funding cycle of 2013. [More]
Researchers describe why current medications only moderately reduce Fragile X symptoms

Researchers describe why current medications only moderately reduce Fragile X symptoms

When you experience something, neurons in the brain send chemical signals called neurotransmitters across synapses to receptors on other neurons. How well that process unfolds determines how you comprehend the experience and what behaviors might follow. In people with Fragile X syndrome, a third of whom are eventually diagnosed with Autism Spectrum Disorder, that process is severely hindered, leading to intellectual impairments and abnormal behaviors. [More]
Whitehead Institute researchers redefine gene mutation that cause Rett syndrome

Whitehead Institute researchers redefine gene mutation that cause Rett syndrome

Whitehead Institute researchers have redefined the function of a gene whose mutation causes Rett syndrome, a neurodevelopmental autism spectrum disorder. This new research offers an improved understanding of the defects found in the neurons of Rett syndrome patients and could lead to novel therapies for the disease. [More]

Bird Brains Shed Light On Speech Learning

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Scientists uncover neural mechanisms that may help in treatment of language disorders in children

USC scientists have discovered a population of neurons in the brains of juvenile songbirds that are necessary for allowing the birds to recognize the vocal sounds they are learning to imitate. [More]
Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

The concept behind gene therapy is simple: deliver a healthy gene to compensate for one that is mutated. New research published today in the Journal of Neuroscience suggests this approach may eventually be a feasible option to treat Rett Syndrome, the most disabling of the autism spectrum disorders. [More]

Scientist receives prestigious USU Medal and 'Order of Military Medical Merit' awards from IRSF

The International Rett Syndrome Foundation (IRSF), the world's largest and most comprehensive not-for-profit organization that funds novel research for treatments and a cure for Rett syndrome, has announced that Steven G. Kaminsky, Ph.D., received two incredibly prestigious awards at the 2013 Annual Family Conference in Midway, Utah this past June. [More]
Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Statins, a class of cholesterol-lowering drugs found in millions of medicine cabinets, may help treat Rett Syndrome, according to a study published today in Nature Genetics. The Rett Syndrome Research Trust (RSRT) funded this work with generous support from the Rett Syndrome Research Trust UK and Rett Syndrome Research & Treatment Foundation. [More]
Researchers describe alterations in long noncoding RNA sequences in Rett syndrome

Researchers describe alterations in long noncoding RNA sequences in Rett syndrome

Researchers at the Epigenetics and Cancer Biology Program at IDIBELL led by Manel Esteller, ICREA researcher and professor of genetics at the University of Barcelona, have described alterations in noncoding long chain RNA sequences in Rett syndrome. [More]
Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Dr. Santosh D'Mello, professor of molecular and cell biology at the University of Texas at Dallas, has received a federal grant for research that may shed light on why and how specific brain cells are affected by Huntington's disease, a devastating, degenerative brain disorder. [More]
Researchers to develop new diagnostic tools and treatments for people with rare diseases

Researchers to develop new diagnostic tools and treatments for people with rare diseases

A multi-million Euro initiative is bringing together researchers from across the world to develop new diagnostic tools and new treatments for people with rare diseases and to connect research data in this area on a global scale. [More]
Researchers pinpoint several inherited mutations in autism

Researchers pinpoint several inherited mutations in autism

While autism clearly runs in some families, few inherited genetic causes have been found. A major reason is that these causes are so varied that it's hard to find enough people with a given mutation to establish a clear pattern. Researchers at Boston Children's Hospital have pinpointed several inherited mutations—among the first to be identified—through an unusual approach: using whole-exome sequencing to study large Middle Eastern families with autism. [More]
Immune dysfunction pinpointed in developmental disorder

Immune dysfunction pinpointed in developmental disorder

Children with neurodevelopmental abnormalities resulting from duplication of the methyl-CpG binding protein 2 gene also have impaired T-helper-cell 1 responses, research shows. [More]

Special issue of Disease Markers explores ASD genetics and biomarker development

Autism spectrum disorders (ASD) are neurodevelopmental disorders typically characterized by difficulties in social interactions and delayed or abnormal language development. Although ASD reportedly affects 1 in 88 people in the United States, to date there have been no distinctive biomarkers to diagnose the disease. [More]