Rhabdomyosarcoma News and Research

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Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Research project receives 25 million U.S. dollars to develop drugs against childhood cancers

Cancer is one of the most common causes of death in children worldwide. A research team in which the University of Würzburg is involved wants to change this – and has now received substantial funding for its work.

6 Mar 2024

Novel assay enhances pediatric cancer treatment by identifying clinically relevant gene fusions

Identification of specific gene fusions is critical for the successful targeted treatment of pediatric cancer patients.

13 Feb 2024

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

In this interview, Jordi Carreras delves into the fascinating world of Cell Painting, a powerful technology gaining momentum in drug discovery. He shares insights into his groundbreaking research, the unique aspects of Phenaros' drug discovery platform, and the synergy between academia and industry.

From ELRIG (UK) Ltd. 1 Nov 2023

Scientific breakthrough could someday save the lives of children with rhabdomyosarcoma

"Every successful medicine has its origin story. And research like this is the soil from which new drugs are born," says Cold Spring Harbor Laboratory Professor Christopher Vakoc.

28 Aug 2023

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

Researchers discover potential new treatment for rhabdomyosarcoma

Researchers from the Leibniz Institute on Aging in Jena and the Brandenburg University of Technology Cottbus-Senftenberg have discovered a novel treatment approach for soft tissue tumors, which are frequently occurring in children and are often malignant.

26 Jul 2023

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Researchers demonstrated the production of cross-clade neutralizing antibodies in response to EV-D68.

19 May 2023

Scientists use enhanced environmental surveillance for poliovirus type 2 detection in London sewage samples

In a new study, researchers investigated molecular properties of type 2 poliovirus (PV) isolates obtained from sewage samples (SS) to detect PV transmission in communities.

17 Oct 2022

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

In a study recently published in Cancer Research, a journal of the American Association for Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center School of Medicine Cancer Center, sought to expand upon his lab's previous research that showed ALT tumors identified by a biomarker known as C-circles share a common biology that confers vulnerabilities to be exploited for cancer therapy.

10 Aug 2022

New discovery may open the door to targeted treatments for two types of rhabdomyosarcoma

A gene that UVA Health researchers discovered is responsible for the deadliest type of brain tumor is also responsible for two forms of childhood cancer, the scientists have found.

28 Jul 2022

Phase I clinical trial of new blocking antibody therapy shows promising results for the treatment of advanced medulloblastoma

Effective and safe treatments are needed for medulloblastoma-;the most common type of cancerous brain tumor in children-;especially for patients whose cancer has spread to the spinal cord.

14 Jul 2022

Improving Patient Recruitment for Clinical Trial Research

In this interview, we speak to Matt Walz, CEO of Trialbee, about the importance of improving patient recruitment and retention within clinical trials.

From Trialbee 23 May 2022

Researchers Identify Potential Target for Rhabdomyosarcoma Recurrence Prevention

In this interview, News-Medical speaks to Anand Patel and Michael Dyer from St. Jude's Children's Research Hospital about their recent research suggesting EGFR inhibitors may prevent rhabdomyosarcoma recurrence.

12 May 2022

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Rhabdomyosarcoma is a type of soft tissue cancer. Scientists at St. Jude Children's Research Hospital studied the population of cells that persists after therapy, causing rhabdomyosarcoma recurrence.

27 Apr 2022

Soy molasses and kudzu roots may help fight against pediatric tumors

Soy molasses and kudzu roots contain isoflavonoids with high antioxidant and cytotoxic activity, scientists have discovered.

30 Mar 2022

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

The National Cancer Institute, part of the National Institutes of Health, recently awarded a five-year, $ $1.9 million grant to C. Patrick Reynolds, M.D., Ph.D., director for the School of Medicine Cancer Center at the Texas Tech University Health Sciences Center.

23 Mar 2022

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated.

18 Sep 2021

New findings shed light on genetic changes that underlie rare, aggressive childhood cancer

A new study could lead to improved decision making in assigning treatments for children with the aggressive cancer rhabdomyosarcoma after revealing key genetic changes underlying development of the disease.

24 Jun 2021

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several types of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations.

23 Feb 2021