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Researchers demonstrate direct connection between NOX proteins and liver fibrosis

Researchers demonstrate direct connection between NOX proteins and liver fibrosis

Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States. [More]

Moerae announces initiation of second MMI-0100 Phase 1 clinical trial for pulmonary disorders

Moerae Matrix Inc. announced today the initiation of its second Phase 1 clinical trial with MMI-0100, a first-in-class inhibitor of MAPKAP kinase 2 (MK2) that is being developed for pulmonary disorders characterized by inflammation and fibrosis. The study, conducted in the United Kingdom, is a double-blind, two-way cross-over design lipopolysaccharide (LPS) challenge study further evaluating the safety and tolerability of MMI-0100 when given via inhalation to healthy subjects who smoke. [More]
Scientists reveal potential therapeutic approach to idiopathic pulmonary fibrosis

Scientists reveal potential therapeutic approach to idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis is a very aggressive form of pulmonary fibrosis and has a particularly poor prognosis. This fatal disease, for which so far no causal therapies exist, is characterized by a massive deposition of connective and scar tissue in the lung, which leads to a progressive loss of lung function and ultimately death. [More]
Vanderbilt researchers hope to give new dexterity to needlescopic surgery with tiny mechanical wrist

Vanderbilt researchers hope to give new dexterity to needlescopic surgery with tiny mechanical wrist

With the flick of a tiny mechanical wrist, a team of engineers and doctors at Vanderbilt University's Medical Engineering and Discovery Laboratory hope to give needlescopic surgery a whole new degree of dexterity. [More]
NeoGraft selects Verasoni Worldwide as marketing communications partner

NeoGraft selects Verasoni Worldwide as marketing communications partner

NeoGraft is pleased to announce the selection of Verasoni Worldwide as integrated marketing communications partner. NeoGraft is a world leader in hair replacement technology serving physicians and patients in the United States and around the world. NeoGraft is the first Class One FDA Listed automated medical device for hair restoration. [More]
New, nontoxic surgical glue helps heal wounds without scar or inflammation

New, nontoxic surgical glue helps heal wounds without scar or inflammation

One of the most basic yet important surgical skills to keep a patient alive and intact may be closing wounds. It seems that doctors will now get the job done with more ease thanks to new, nontoxic surgical glue that instantly seals a bleeding wound and helps it heal without a scar or inflammation. [More]
UT Southwestern dermatologist improves technique to treat skin discoloration from vitiligo

UT Southwestern dermatologist improves technique to treat skin discoloration from vitiligo

A UT Southwestern Medical Center dermatologist has improved a technique to transplant pigment cells that can repair the affected area of skin discoloration from vitiligo. [More]
Pioneering Southampton research investigates health impacts of spaceflight

Pioneering Southampton research investigates health impacts of spaceflight

Pioneering research from the University of Southampton into the health impacts of spaceflight has been identified as a possible experiment to be conducted by British astronaut Tim Peake on his maiden voyage to the International Space Station later this year. [More]
Penn State Hershey cardiologist explains causes and symptoms of heart attack

Penn State Hershey cardiologist explains causes and symptoms of heart attack

It's possible to have a heart attack and not even know it. Maybe it's because you're stoic when it comes to pain and fatigue. Or maybe you write off your symptoms as heartburn or indigestion. It's even possible that your own body is kicking up its reserves to mask symptoms of what is happening inside. [More]
Implantable microfluid system can efficiently stabilize intraocular pressure

Implantable microfluid system can efficiently stabilize intraocular pressure

Elevated or diminished eye pressure impairs our ability to see, and in the worst cases, can even lead to blindness. Until now, there has been no effective long-term treatment. In response, Fraunhofer researchers are developing an implantable microfluid system that can efficiently and durably stabilize intraocular pressure. [More]
Cell transplantation researchers successfully treat laboratory rats modeled with severe burns

Cell transplantation researchers successfully treat laboratory rats modeled with severe burns

Cell transplantation researchers have successfully used bone marrow-derived mesenchymal stromal cells (MSCs) to treat a variety of diseases and conditions. Now, using injections of MSCs, a research team in Brazil has successfully treated laboratory rats modeled with severe burns. [More]
Researchers develop new implantable drug-delivery system using nanowire

Researchers develop new implantable drug-delivery system using nanowire

A team of researchers has created a new implantable drug-delivery system using nanowires that can be wirelessly controlled. [More]
Researchers explore the science of exosomes in heart repair

Researchers explore the science of exosomes in heart repair

A little more than a decade ago, researchers discovered that all cells secrete tiny communications modules jammed with an entire work crew of messages for other cells. Today, a team of researchers, led by stem cell researcher Raj Kishore, PhD, Director of the Stem Cell Therapy Program at the Center for Translational Medicine at Temple University School of Medicine, is harnessing the communications vesicles excreted by stem cells and using them to induce the damaged heart to repair itself. [More]
CellResearch receives new patent approval from USPTO for stem cell technology

CellResearch receives new patent approval from USPTO for stem cell technology

CellResearch Corporation Pte Ltd, a Singaporean company that specializes in stem cell technology, has received approval for its latest patent on 6 May 2015 from the US Patent and Trademark Office. [More]
Autoantibodies play major role in IPF patients with acute exacerbations

Autoantibodies play major role in IPF patients with acute exacerbations

Patients with acute exacerbations of idiopathic pulmonary fibrosis responded well to therapies similar to those used to treat autoimmune diseases, according to findings published today in PLOS ONE. The study suggests that autoantibodies — implicated in many autoimmune diseases such as rheumatoid arthritis or lupus — also play an important role in patients with acute exacerbations of IPF, a devastating lung disease. [More]
New study reports more practical approach to heal the heart after a heart attack

New study reports more practical approach to heal the heart after a heart attack

Stem cell have been the main focus of healing therapy research because they can morph into new cells, and using a patient's own stem cells will not induce an autoimmune response. For healing after a heart attack, the ideal time to administer these therapies is when reopening the clogged blood vessel because the heart is easily accessible. While stem cells show promise for heart attack treatment, the process of harvesting and reintroducing the cells—which can take days or weeks—is too slow for this window. [More]
New therapeutic target discovered for idiopathic pulmonary fibrosis

New therapeutic target discovered for idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease for which as yet no causal therapy exists. It is, however, known that the lung interstitium - the connective tissue between the air sacs in the lower part of the lung - is affected. [More]
Actavis receives FDA approval to market NATRELLE INSPIRA round gel-filled textured breast implants

Actavis receives FDA approval to market NATRELLE INSPIRA round gel-filled textured breast implants

Actavis plc, which recently completed the acquisition of Allergan, Inc., today announced that the company has received approval from the U.S. Food and Drug Administration to market NATRELLE INSPIRA round gel-filled textured breast implants, offering women undergoing reconstruction, augmentation or revision surgery another breast shaping option for a customized result. [More]
Study explores 'laser welding' for sealing corneal transplants

Study explores 'laser welding' for sealing corneal transplants

Some 30,000 years ago, prehistoric man wielded animal bones as needles to suture otherwise lethal wounds. This tactic has been used, and improved upon, over time and remains the basis of surgical procedures conducted today. Even with radical new surgical techniques, which rely on metallic and polymeric staples or chemical adhesives to seal incisions, infection and permanent scarring remain major concerns. The success of any wound closure is entirely dependent on the physician's skill set alone. [More]
Scar management: an interview with Adele Atkinson, Associate Professor, School of Nursing

Scar management: an interview with Adele Atkinson, Associate Professor, School of Nursing

Scarring has been shown to have a significant impact on patients’ lives. As well as the physical burden associated with skin scarring, psychological strains can also negatively affect the quality of life for patients, with the majority (56%) considering themselves to be ‘abnormal’ due to their scars... [More]
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