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TSRI scientists discover new method for harnessing venoms for therapeutic use

TSRI scientists discover new method for harnessing venoms for therapeutic use

Scorpions, snakes, snails, frogs and other creatures are thought to produce tens or even hundreds of millions of distinct venoms. These venoms have been honed to strike specific targets in the body. [More]
Mitoxantrone for MS linked to colorectal cancer risk

Mitoxantrone for MS linked to colorectal cancer risk

Treatment with mitoxantrone for multiple sclerosis carries only a mildly increased risk of malignancy overall, but the risk of colorectal cancer and leukaemia is heightened, researchers have found. [More]
Researchers find genetic mutations linked to increased risk factor for PTSD

Researchers find genetic mutations linked to increased risk factor for PTSD

In the largest study of DNA samples from service members with Post-Traumatic Stress Disorder (PTSD), researchers have identified genetic mutations that may be associated with an increased risk factor for PTSD. [More]
New collaborative research center to investigate promising aspects of mucosal immunology

New collaborative research center to investigate promising aspects of mucosal immunology

Immunology - and the idea that many diseases can best be addressed by boosting the body's own immune response - is one of the hottest areas in medical research and clinical treatment. [More]
Penn State researchers link mutation in common virus to fatal brain disease

Penn State researchers link mutation in common virus to fatal brain disease

Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often-fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine. [More]
Taking pregabalin drug during pregnancy could lead to major birth defects

Taking pregabalin drug during pregnancy could lead to major birth defects

A drug commonly used to treat pain, epilepsy, anxiety and other brain health disorders may be associated with an increased risk of major birth defects, according to a study published in the May 18, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Wyss Institute partners with ReWalk to accelerate development of wearable, soft exosuits

Wyss Institute partners with ReWalk to accelerate development of wearable, soft exosuits

The Wyss Institute for Biologically Inspired Engineering at Harvard University has entered into a collaboration with ReWalk Robotics Ltd., to accelerate the development of the Institute's lightweight, wearable soft exosuit technologies for assisting people with lower limb disabilities. [More]
Low levels of vitamin D in Orkney may explain reason for higher rates of multiple sclerosis

Low levels of vitamin D in Orkney may explain reason for higher rates of multiple sclerosis

Holidays abroad may hold the key to tackling Scotland's vitamin D deficiency, research suggests. [More]
Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

The motor protein Myo1c binds to Neph1, a protein crucial for ensuring effective filtration by the kidney, and serves as one mode of its cellular transport, according to findings by investigators at the Medical University of South Carolina and their collaborators reported in the May 16, 2016 issue of Molecular and Cellular Biology. [More]
Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

The hygiene hypothesis refers to the idea that decreased exposure to certain infectious agents (because of better hygiene) is the reason why we have seen an increase in inflammatory diseases in the developed world. [More]
Study links multiple sclerosis in children to abundance of specific gut bacteria

Study links multiple sclerosis in children to abundance of specific gut bacteria

In a recent study, children with multiple sclerosis had differences in the abundance of specific gut bacteria than children without the disease. Certain types of bacteria were either more or less abundant in children with multiple sclerosis. [More]
Unlocking the dark proteome: an interview with Dr Kriwacki

Unlocking the dark proteome: an interview with Dr Kriwacki

The term dark proteome refers to proteins whose structural features and thus functions are not well understood. Many proteins within the dark proteome do not fold into stable three-dimensional structures. These proteins are called intrinsically disordered proteins (IDPs) and feature highly flexible, disordered confirmations. [More]
On-treatment relapse drives disability accrual in MS patients

On-treatment relapse drives disability accrual in MS patients

Frequent relapse activity appears to be a key driver of disability accrual in patients with relapse-onset multiple sclerosis, indicates a study of patients receiving first-line injectable disease-modifying treatment. [More]

Kent researchers perform first clinical trials of bionic legs for patients

Expert clinicians and engineers at the University of Kent are carrying out the first clinical trials of robotic legs for patients [More]
New national survey reveals that asthma patients most frequently use rescue inhaler

New national survey reveals that asthma patients most frequently use rescue inhaler

In a new national survey of asthma patients, Health Union, and its new online community Asthma.net, reveals that most were satisfied with the care they received; however, the most frequently used form of treatment, at 89%, is the rescue inhaler. [More]
Mitoxantrone drug users more likely to develop colorectal cancer

Mitoxantrone drug users more likely to develop colorectal cancer

The multiple sclerosis (MS) drug mitoxantrone may be associated with an increased risk of colorectal cancer, according to a study published in the May 11, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology. Mitoxantrone suppresses the immune system. [More]
Two statistically significant genetic variants may be linked to increased PTSD risk in veterans

Two statistically significant genetic variants may be linked to increased PTSD risk in veterans

In a massive analysis of DNA samples from more than 13,000 U.S. soldiers, scientists have identified two statistically significant genetic variants that may be associated with an increased risk of post-traumatic stress disorder (PTSD), an often serious mental illness linked to earlier exposure to a traumatic event, such as combat and an act of violence. [More]
MNI scientists move a step forward in efforts to treat hereditary spastic paraplegia

MNI scientists move a step forward in efforts to treat hereditary spastic paraplegia

Scientists at the Montreal Neurological Institute and Hospital have identified novel gene mutations that cause hereditary spastic paraplegia (HSP), a step forward in efforts to treat this debilitating disease. [More]
Pulmonary hypertension impacts walking ability in SSc patients

Pulmonary hypertension impacts walking ability in SSc patients

The results of a meta-analysis show the adverse impact pulmonary hypertension has on the walking stamina of patients with systemic sclerosis. [More]
Scientists use non-invasive way to track rapid myelination of nerve fibers in children's brains

Scientists use non-invasive way to track rapid myelination of nerve fibers in children's brains

Much like electricity traveling down wires, nerve impulses in our brain travel along nerve fibers. And just as wires need insulation to function well, nerve fibers, too, rely on a kind of insulation called myelin, a fatty substance that protects them and increases the speed at which nerve impulses travel. [More]
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