Short Chain Fatty Acids News and Research

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Butyrate and propionate are two important short-chain fatty acids (SCFAs) produced in the human gut. They have been shown to have significant immune system effects in the intestinal mucosa, by inducing the differentiation of T-regulatory cells via inhibition of histone deacetylase (HDAC). This enzyme keeps chromatin from unwinding and, therefore, inhibits gene transcription.

Study shows that high Mediterranean dietary adherence lowers systemic inflammation in elders

The relationship between high Mediterranean dietary pattern (MDP) adherence and decreased low-grade systemic inflammation.

7 May 2024

Inulin fiber exacerbates inflammatory bowel disease, study finds

Inulin, a type of fiber found in certain plant-based foods and fiber supplements, causes inflammation in the gut and exacerbates inflammatory bowel disease in a preclinical model, according to a new study by Weill Cornell Medicine investigators.

2 May 2024

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

A low-fiber “Western diet” causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection.

29 Apr 2024

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

Study evaluates the role of cruciferous vegetables and their bioactive components in mitigating inflammatory bowel disease through in vitro, in vivo, and preliminary clinical investigations, suggesting a promising therapeutic avenue.

21 Apr 2024

Breast milk's secret weapon against RSV revealed in new study

Researchers explored how human milk oligosaccharides (HMOs) protect infants from respiratory syncytial virus (RSV), suggesting that these components in breast milk may prevent or reduce the severity of RSV infections through multiple mechanisms including gut microbiome modulation and direct antiviral actions.

15 Apr 2024

Gut bacteria play a pivotal role in obesity's impact on body fat metabolism

Review explores the complex interplay between gut microbiota dysregulation in obesity and its impacts on white and brown adipose tissue metabolism, focusing on direct and indirect effects on mitochondria, highlighting potential avenues for obesity treatment through microbiota-focused strategies.

11 Apr 2024

Maternal influences on food allergy prevention: A closer look at diet and environment

Review assesses how maternal diet and environmental factors during pregnancy influence the prevention of food allergies in offspring, underlining the importance of a balanced diet and questioning the efficacy of allergen avoidance.

9 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

From gut to mind: Exploring prebiotics and probiotics as dual fighters against depression and obesity

The interactions between depression and nutrition, coupled with exercise.

4 Apr 2024

Study reveals skin bacteria removal boosts brain attention signals

Researchers discover a link between skin microbiota and brain cognitive functions, showing that removing skin bacteria may enhance attention levels.

3 Apr 2024

Novel lipids in traditional herbal teas unlock potential health gains

The lipids in some herbal teas have been identified in detail for the first time, preparing the ground for investigating their contribution to the health benefits of the teas.

29 Mar 2024

Unique bacteria colonize the gut shortly after birth and make serotonin to educate gut immune cells

A recent study revealed that neonatal gut bacteria produce serotonin and down-regulate monoamine oxidase A (MOA) to limit serotonin breakdown, thereby promoting immune tolerance.

20 Mar 2024

Study highlights causal associations between gut microbes and hypothyroidism

The association between the microbial community of the gut and hypothyroidism.

20 Mar 2024

Study analyzes effects of burn injury on the gut microbiota and mucus barrier in mice

The gut microbiota, a complex ecosystem within the human intestinal tract, is increasingly recognized for its vital role in human health and disease.

14 Mar 2024

Thinking of switching to Quorn? It could help lower bad cholesterol by 10%

A new Clinical Nutrition study investigated whether a home-based and remotely-delivered dietary intervention containing mycoprotein could influence cholesterol and other biomarkers of cardiovascular disease (CVD) in overweight adults.

6 Mar 2024

The impact of quinoa bioactive compounds on gut health

Researchers review the beneficial impacts of quinoa and its bioactive compounds, particularly its effects on intestinal microflora.

4 Mar 2024

Gut bacteria diversity linked to body weight, athletes show healthier profiles

Systematic review reveals gut microbiome variations correlate with body composition changes across lifespan, highlighting differences between obese individuals and athletes.

29 Feb 2024

Can dietary patterns impact stomach cancer risk?

Eating patterns and indices related to gastric cancer and explored their association with stomach cancer risk.

22 Feb 2024

Missing gut microbes after antibiotics and a high-fat diet may be to blame for sugar-free candy and gum giving you gas

A recent Cell study showed how a high-fat diet and antibiotic exposure could trigger sorbitol intolerance by depleting Clostridia from the gut microbiota.

20 Feb 2024

Twin study investigates the role of the microbiome as a modifier in mental disorders

Researchers examined whether the influence of gut microbiome perturbations on various biological processes, such as the dysregulation of the hypothalamic–pituitary–adrenal axis, performance of the immune system, and the production of neurotransmitters and short-chain fatty acids contributed to the manifestation and progression of mental health disorders such as anxiety, depression, and eating disorders.

15 Feb 2024