Single Photon Emission Computed Tomography (SPECT) News and Research

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In vivo dopaminergic imaging strongly correlates with brain pathology

Striatal dopamine transporter binding, assessed using single-photon emission computed tomography, is strongly correlated with substantia nigra cell counts assessed at postmortem, say the authors of a study.

11 Aug 2014

Cardium reports positive results from Generx Ad5FGF-4 Phase 3 study for treatment of myocardial ischemia

Taxus Cardium Pharmaceuticals Group Inc. will report today at the Biotechnology Industry Organization’s 2014 BIO International Convention on a pre-specified interim analysis from its international ASPIRE Phase 3 registration clinical study of Generx Ad5FGF-4, Cardium Therapeutics’ angiogenic gene therapy product candidate for patients with myocardial ischemia due to coronary artery disease.

25 Jun 2014

REM sleep disorder: A sign of impending neurodegenerative disease

How many millions of people suffer from sleep disturbance? One sleep disorder in particular, called REM behavior disorder, could be a sign of impending neurodegenerative disease, including Parkinson's and dementia, say scientists presenting their research at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

10 Jun 2014

Study shows melatonin hormone may inhibit tumor growth and cell production

An early stage study shows melatonin - a hormone that regulates the body's sleep and awake cycles - may have the potential to help slow the growth of certain breast cancer tumors, according to researchers from Henry Ford Hospital in Detroit and Foundation for Research Support of the State of S-o Paulo.

28 Jan 2014

Biomarker used to diagnose brain injury shows early promise for assessing heart inflammation

A biomarker widely used to diagnose brain injury has shown early promise for assessing the severity of heart inflammation, or myocarditis, find researchers at Columbia University's Mailman School of Public Health, Johns Hopkins, and the Mayo Clinic.

28 Jan 2014

Research highlights potential of newly developed radiopharmaceuticals for imaging melanoma metastases

With low survival rates for patients with metastasized melanoma, accurate staging and effective treatments are critical to extending life. New research published in the Journal of Nuclear Medicine highlights the potential of newly developed radiopharmaceuticals with benzamide for the imaging of metastases and as a targeted systemic therapy.

8 Jan 2014

Research findings offer new hope for millions of traumatic brain injury patients

Every year, nearly two million people in the United States suffer traumatic brain injury (TBI), the leading cause of brain damage and permanent disabilities that include motor dysfunction, psychological disorders, and memory loss. Current rehabilitation programs help patients but often achieve limited success.

19 Nov 2013

World’s first preclinical Magnetic Particle Imaging (MPI) system announced by Bruker

At the 2013 World Molecular Imaging Congress (WMIC, www.wmicmeeting.org), Bruker today announced the world’s first Magnetic Particle Imaging (MPI) system, an entirely new technology for preclinical imaging. The addition of MPI as a complementary preclinical imaging technique for disease studies, translational research and drug discovery, has significant potential in helping researchers gain new insights into disease processes at the organ, cellular and molecular level.

From Bruker BioSpin - NMR, EPR and Imaging 19 Sep 2013

Multimodal animal bed introduced by Bruker

Today, at the 2013 World Molecular Imaging Congress (WMIC), Bruker introduces a new multimodal animal bed enabling multiple sequential imaging sessions in preclinical research with robust repositioning between scans, while avoiding unwanted motion of the animal during the investigation. This optimizes results for image fusion, combined processing and evaluation of preclinical research applications requiring multiple imaging modalities across multiple systems.

From Bruker BioSpin - NMR, EPR and Imaging 19 Sep 2013

Endocyte, Nihon Medi-Physics Collaborate On Companion Imaging Diagnostic

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6 Sep 2013

Endocyte, Nihon Medi-Physics Collaborate On Companion Imaging Diagnostic

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6 Sep 2013

Navidea Biopharmaceuticals signs SPA agreements with FDA for NAV5001 Phase 3 program

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that it has reached agreement with the U.S. Food and Drug Administration for two special protocol assessments for the Company's pivotal Phase 3 program with NAV5001 as an aid in the differential diagnosis of Parkinsonian Syndromes from non-Parkinsonian tremor.

23 Aug 2013

Neuroimaging specialists use tanners to identify whether UV light triggers brain's pleasure sensors

Neuroimaging specialists at UT Southwestern Medical Center are launching the first clinical trial involving frequent and infrequent tanners designed to identify whether UV light triggers the brain's pleasure sensors.

13 Aug 2013

PSMA enzyme could become hallmark of new generation of biomarkers for prostate cancer treatment

No matter where they have hidden, metastatic prostate cancer cells still express some of the same signaling as normal prostate cells; in some cases even more so, as with the PSMA enzyme. Harnessing this enzyme could mean the beginning of a new platform for prostate cancer detection, staging, treatment and post-treatment monitoring, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

12 Jun 2013

Hybrid molecular imaging technique helps doctors identify diabetic foot infection

Researchers are kick-starting better diabetic foot care and promoting reduced radiation dose with a new take on a hybrid molecular imaging technique. By targeting both bone cell activity and immune response and improving imaging data interpretation, doctors can better distinguish diabetic foot infection from another common foot condition that often requires an additional bone-marrow scan for definitive diagnosis, say researchers presenting a study at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

12 Jun 2013

Johns Hopkins expert in brain imaging receives 2013 Paul C. Aebersold Award

A Johns Hopkins expert in brain imaging, Dean F. Wong, M.D., Ph.D., has been honored with the prestigious 2013 Paul C. Aebersold Award for his contributions over the past 30 years in applying basic science to the field of nuclear medicine.

11 Jun 2013

New protocol for reducing the use of SPECT SPI is found to be diagnostically safe

A new stress test protocol that investigates reducing the use of perfusion imaging in low risk patients undergoing SPECT myocardial perfusion imaging for possible angina symptoms was found to be diagnostically safe, revealed a US retrospective analysis.

6 May 2013

Preclinical study of cabozantinib in prostate cancer bone metastasis model presented at AACR meeting

Exelixis, Inc. announced the presentation of preclinical data that provide insight into the mechanism of action of its lead compound, cabozantinib, with respect to its activity against prostate cancer tumors that have metastasized to the bone.

11 Apr 2013

V/Q imaging can detect early stages of COPD

In vivo ventilation/perfusion (V/Q) imaging can detect early changes to the lung caused by cigarette smoke exposure and provides a noninvasive method for studying lung dysfunction in preclinical models, according to research published in the April issue of The Journal of Nuclear Medicine.

2 Apr 2013

Two novel radiolabeled small molecules can help detect prostate cancer

Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published this month in The Journal of Nuclear Medicine.

6 Mar 2013

Single Photon Emission Computed Tomography (SPECT) News and Research

In vivo dopaminergic imaging strongly correlates with brain pathology

Cardium reports positive results from Generx Ad5FGF-4 Phase 3 study for treatment of myocardial ischemia

REM sleep disorder: A sign of impending neurodegenerative disease

Study shows melatonin hormone may inhibit tumor growth and cell production

Biomarker used to diagnose brain injury shows early promise for assessing heart inflammation

Research highlights potential of newly developed radiopharmaceuticals for imaging melanoma metastases

Research findings offer new hope for millions of traumatic brain injury patients

World’s first preclinical Magnetic Particle Imaging (MPI) system announced by Bruker

Multimodal animal bed introduced by Bruker

Endocyte, Nihon Medi-Physics Collaborate On Companion Imaging Diagnostic

Endocyte, Nihon Medi-Physics Collaborate On Companion Imaging Diagnostic

Navidea Biopharmaceuticals signs SPA agreements with FDA for NAV5001 Phase 3 program

Neuroimaging specialists use tanners to identify whether UV light triggers brain's pleasure sensors

PSMA enzyme could become hallmark of new generation of biomarkers for prostate cancer treatment

Hybrid molecular imaging technique helps doctors identify diabetic foot infection

Johns Hopkins expert in brain imaging receives 2013 Paul C. Aebersold Award

New protocol for reducing the use of SPECT SPI is found to be diagnostically safe

Preclinical study of cabozantinib in prostate cancer bone metastasis model presented at AACR meeting

V/Q imaging can detect early stages of COPD

Two novel radiolabeled small molecules can help detect prostate cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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