Sjogren's syndrome is a chronic autoimmune syndrome characterized by lymphocyte infiltration of salivary glands, resulting in symptomatic eye and mouth dryness. Sjogren's syndrome can be associated with extraglandular presentations, such as musculoskeletal features including fatigue and fibromyalgia, in nearly 50% of patients, and fewer patients complain of arthralgias. According to the Sjogren's Syndrome Foundation, the condition affects approximately two million to four million Americans, mostly middle-age women.