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Study reveals link between HPV infection and SCC in organ transplant recipients

A new study published in the American Journal of Transplantation reveals an association between the human papillomavirus (betaPV) infection and cutaneous squamous cell carcinoma (SCC) in organ transplant recipients.

13 Jul 2011

Blood cancer drug trial results questioned by FDA

U.S. drug reviewers might limit the use of a Seattle Genetics Inc’s experimental blood cancer drug due to the narrow scope of its clinical trials. According to papers released Tuesday by the Food and Drug Administration (FDA), it requests an advisory panel to consider the drug, under the proposed trade name Adcetris known chemically as brentuximab vedotin, for use in previously treated patients with Hodgkin's lymphoma and anaplastic large cell lymphoma (ALCL).

13 Jul 2011

Cancer Cell publishes results of melanoma study

Metamark Genetics, Inc., a privately-held oncology-focused molecular diagnostics company, today announced results from a melanoma study published in Cancer Cell.

12 Jul 2011

Specific miRNAs play a key role in melanoma metastasis

Researchers at the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, identified for the first time the key role specific microRNAs play in melanoma metastasis to simultaneously cause cancer cells to invade and immunosuppress the human body's ability to fight abnormal cells.

12 Jul 2011

Microneedle patches may target dentritic cells more efficiently and induce immunity against HIV

Applying a vaccine patch to the skin with thousands of tiny micro-needles could help boost the body's immune response and prevent the spread of life-threatening infections like HIV and TB, a major Cardiff University study aims to uncover.

11 Jul 2011

Fibrin key to protection during gram-negative sepsis

New research from the Trudeau Institute may help to explain why anticoagulant therapies have largely failed to extend the lives of patients with sepsis. The study was led by Deyan Luo, a postdoctoral fellow in Stephen Smiley's laboratory. It shows that fibrin, a key product of the blood clotting process, is critical for host defense against Yersinia enterocolitica, a gram-negative bacterium that causes sepsis in humans and experimental mice.

11 Jul 2011

New corticosteroid with cream-like base

Upsher-Smith Laboratories, Inc. announced the launch of Trianex 0.05% (Triamcinolone Acetonide Ointment), a prescription topical corticosteroid offering the feel of a cream with the strength of an ointment.

11 Jul 2011

FDA approves expansion of St. Jude Medical's BROADEN deep brain stimulation study for depression

St. Jude Medical, Inc., a global medical device company, today announced that the U.S. Food and Drug Administration (FDA) has granted approval for expansion of its BROADEN (BROdmann Area 25 DEep brain Neurostimulation) study for depression. This expansion will allow a maximum of 20 sites across the U.S. to enroll up to 125 patients.

11 Jul 2011

'The Aging Myth' achieves top rank in New York Times Best Seller List

In only its first week of bookstore sales, "The Aging Myth," by Joseph Chang, Ph.D., has already reached #2 on the New York Times Best Seller List for its frank look at aging and a scientific approach to understanding how to combat aging at the genetic level.

11 Jul 2011

Researchers identify new antibiotic-resistant gonorrhea strain

An international research team has discovered a strain of gonorrhea resistant to all currently available antibiotics. This new strain is likely to transform a common and once easily treatable infection into a global threat to public health.

11 Jul 2011

MSU professor focuses on new formulation for old drug to treat parasitic diseases

With the help of another $2 million in funding from the Bill & Melinda Gates Foundation, researchers are moving closer to setting up human clinical trials for a reformulated drug that could be the linchpin of treatment efforts against two debilitating tropical diseases.

11 Jul 2011

Scientists convert brain cells into cardiomyocytes

For the past decade, researchers have tried to reprogram the identity of all kinds of cell types. Heart cells are one of the most sought-after cells in regenerative medicine because researchers anticipate that they may help to repair injured hearts by replacing lost tissue.

11 Jul 2011

Scientists discover seven new gene variants that increase risk of prostate cancer

Cancer Research UK-funded scientists have taken a further step to identifying men at a greater risk of prostate cancer with the discovery of seven new variants in the human genome that increase the chances of developing the disease.

11 Jul 2011

Study reports high prevalence of vitamin D insufficiency in patients with psoriatic arthritis

New research reports a high prevalence of vitamin D insufficiency and deficiency among patients with psoriatic arthritis. Seasonal variation in vitamin D levels was not observed in patients in southern or northern locations.

11 Jul 2011

Belly button full of bugs: Study

Researchers have found nearly 1,400 strains of bacteria in the human navel. The North Carolina State University's ‘Belly Button Biodiversity Study’ found 662 unrecognized strains - which could be unique new species.

10 Jul 2011

Scientists discover mechanism that enables developing cancer cells to sustain abnormal growth

Scripps Research Institute scientists have discovered a basic mechanism that can enable developing cancer cells to sustain abnormal growth. The finding is expected to lead to the targeting of this mechanism with drugs and diagnostic techniques.

8 Jul 2011

Scientists track public health trends through Twitter

Twitter allows millions of social media fans to comment in 140 characters or less on just about anything: an actor's outlandish behavior, an earthquake's tragic toll or the great taste of a grilled cheese sandwich.

8 Jul 2011

Novartis Afinitor Phase III trial on tuberous sclerosis meets primary endpoint

Novartis Pharmaceuticals Corporation announced today Phase III trial results that showed more than one-third of patients taking Afinitor tablets experienced a 50% or greater reduction in the size of their subependymal giant cell astrocytomas, non-cancerous brain tumors associated with tuberous sclerosis complex.

8 Jul 2011

Heartworm medication Ivermectin prevents malaria transmission in Africa

A cheap, common heartworm medication that is already being used to fight other parasites in Africa could also dramatically interrupt transmission of malaria, potentially providing an inexpensive tool to fight a disease that kills almost 800,000 people each year, according to a new study published in the July edition of the American Journal of Tropical Medicine and Hygiene.

7 Jul 2011

Researchers find new molecule that controls pain sensitivity from UVB irradiation

Researchers at King's College London have found a molecule in the body which controls sensitivity to pain from UVB irradiation, identifying it as a new target for medicines to treat pain caused by other common inflammatory conditions such as arthritis.

7 Jul 2011