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FDA clears Nuvo's IND for Lidocaine Spray formulation

Nuvo Research Inc., a specialty pharmaceutical company dedicated to building a portfolio of products for the topical treatment of pain, today announced that the U.S. Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application filed May 27, 2011 for a novel topical Lidocaine Spray formulation (NRI-ANA), allowing for initiation of Phase 1 studies.

29 Jun 2011

Protein c-JUN protects both tumour accelerating gene and tumour suppressor gene

The process of cell division is tightly regulated, as mistakes may lead to cancer. The so-called c-JUN protein has been fingered as causing tumours in both skin and liver. It has long been known to have a direct role in reducing the expression of a gene (p53) that leads to the death of abnormal cells and to activate transcription of a further gene (CyclinD1) that directly promotes cell division.

28 Jun 2011

RCSI researchers identify novel drug target for osteomyeltitis

New research from the Royal College of Surgeons in Ireland (RCSI) has identified a novel drug target for the treatment of infection in bone.

28 Jun 2011

Cynosure announces acquisition of HOYA ConBio's aesthetic laser business

Building on its reputation as a global technology leader in laser and light-based aesthetic systems, Cynosure, Inc. today announced that it has acquired the assets of the aesthetic laser business of HOYA ConBio, a wholly owned subsidiary of Japan-based HOYA Corporation, for $24.5 million in cash. HOYA ConBio is based in Fremont, California.

28 Jun 2011

Study links physiological responses to anger with reduction of empathy after severe TBI

Egocentric, self-centred, and insensitive to the needs of others: these social problems often arise in people with severe traumatic brain injury (TBI) and have been attributed in part to a loss of emotional empathy, the capacity to recognise and understand the emotions of other people.

28 Jun 2011

Experts discuss therapeutic potential of adipose-derived stem cells at ICAS Conference

Esthetic therapies with stem cells from autologous fat are revolutionizing cosmetic surgery: Ever more women prefer breast augmentations with autologous stem cells over silicone implants. The world's leading experts recently met at the ICAS Conference in Istanbul to discuss the therapeutic potential of stem cells from fat tissue.

28 Jun 2011

Tissue-engineered blood vessels from donor skin cells successfully implanted in patients

For the first time, blood vessels created in the lab from donor skin cells were successfully implanted in patients. Functioning blood vessels that aren't rejected by the immune system could be used to make durable shunts for kidney dialysis, and potentially to improve treatment for children with heart defects and adults needing coronary or other bypass graft surgery.

28 Jun 2011

Body sculpting technique eliminates abdominal fat with few side effects

A "body sculpting" technique using high-intensity focused ultrasound to eliminate unwanted abdominal fat effectively reduces waist circumference, with only minor pain and side effects, reports a study in the July issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

28 Jun 2011

Lean gene and heart disease risk

According to a new study published Sunday, being lean may not always lead to a lower risk of heart disease and diabetes. The researchers have successfully identified a gene linked both to having a lean body and to a higher risk of metabolic diseases.

27 Jun 2011

Eating more soluble fiber and engagement in moderate activity reduces belly fat

All fat is not created equal. Unsightly as it is, subcutaneous fat, the fat right under the skin, is not as dangerous to overall health as visceral fat, the fat deep in the belly surrounding vital organs.

27 Jun 2011

Cardium to purchase Transdel's business assets

Cardium Therapeutics today announced that it had entered into an agreement with Transdel Pharmaceuticals to acquire substantially all of Transdel's business assets including a Phase 3 product candidate Ketotransdel (TDLP-110), which is a topically-administered analgesic for the treatment of musculoskeletal pain.

27 Jun 2011

New 3D herpes infection model brings hope

Herpes infections on the lips, in the eyes or on the nose are painful, long-lasting and unpleasant. A new 3D herpes infection model brings hope: active ingredients and new treatments can be reliably tested with this model. Animal tests could soon be a thing of the past.

27 Jun 2011

Flamel, Digna Biotech enter joint development agreement for multiple products

Flamel Technologies SA and Digna Biotech SL today announced that the two companies have entered into a joint development agreement for the pre-clinical and clinical development of multiple products.

27 Jun 2011

Youngevity to acquire Bellamora

Youngevity Essential Life Sciences, which sells an extensive line of nutritional supplements and health and personal care products, announced today that it has signed a definitive agreement to acquire the distributor base and product line of Bellamora, a Tampa, Florida-based marketer of skin care products.

27 Jun 2011

Yissum, BioLineRx sign license deal to develop and commercialize BL-7040 for IBD

BioLineRx, a biopharmaceutical drug development company, and Yissum Research Development Company Ltd., the Technology Transfer Company of the Hebrew University of Jerusalem, announced today that they have signed a worldwide, exclusive license agreement for BioLineRx to develop and commercialize BL-7040, an orally available Phase II ready molecule for treating Inflammatory Bowel Disease (IBD) and other inflammatory diseases.

27 Jun 2011

Less body fat may increase risk of metabolic diseases

Having a lower percentage of body fat may not always lower your risk for heart disease and diabetes, according to a study by an international consortium of investigators, including two scientists from the Institute for Aging Research of Hebrew SeniorLife, an affiliate of Harvard Medical School (HMS).

27 Jun 2011

Diabetic neuropathy patients with wounds must protect themselves from pets

In a case study that illustrates the need for people with diabetes to be cautious of foot injuries and to protect themselves from pets, a woman with numbness in her feet caused by diabetic neuropathy slept through a traumatic episode in which her Jack Russell terrier chewed off part of her slightly infected big toe, according to an article published in this month's issue of the Journal of the American Podiatric Medical Association.

24 Jun 2011

Cocaine contaminated with livestock de-worming drug causes painful purpura

If the obvious reasons for avoiding recreational drug use aren't off-putting enough, physicians have yet another detrimental consequence to add to the list - crusty, purplish areas of dead skin that are extremely painful and can open the door to nasty infections.

24 Jun 2011

PCIB reports main results of Amphinex Phase I/II study against multiple cancers

PCI Biotech (PCIB) the Norwegian biopharmaceutical company, reported today the main results of the completed Phase I/II study of the new component Amphinex in the combination productPC-A11, where Amphinex is used in combination with the cytotoxic agent bleomycin.

24 Jun 2011

Scientists develop new NO delivery system to fortify effects of Viagra in the body

Scientists are reporting development and successful initial tests of a potential new delivery system for the biological signaling agent responsible for the effects of Viagra.

24 Jun 2011