Small Molecules News and Research

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Researchers uncover the biology behind insulin production

The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis.

25 Jul 2023

USC study reveals key details about how cancer cells metastasize

A surprising finding from USC reveals key details about how cancer cells metastasize and suggests new therapeutic approaches for halting their spread.

24 Jul 2023

Arrayjet announces collaboration with Chemspace to augment its small molecule microarray services for drug discovery

Arrayjet, a leading provider of inkjet liquid-handling solutions, today announced that it has partnered with Chemspace, the largest online catalogue of small molecules and biologics, to augment and streamline the Company’s small molecule microarray (SMM) service offering.

From Arrayjet Ltd 19 Jul 2023

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Francesca Marassi, PhD, professor and chair of biophysics at the Medical College of Wisconsin (MCW), has been awarded a five-year, $13 million program project grant (PPG) by the National Institutes of Health (NIH) to study misplaced calcification in the eyes and brains of patients suffering from age-related macular degeneration (AMD) and Alzheimer's disease (AD).

18 Jul 2023

Researchers develop a chemical approach to reverse aging

In a groundbreaking study, researchers have unlocked a new frontier in the fight against aging and age-related diseases.

12 Jul 2023

Scientists identify signal essential for blood-brain barrier formation

What makes the vital layer of protective cells around the brain and spinal cord -; the blood-brain barrier -; more or less permeable has been one of the more mystifying questions in neuroscience.

12 Jul 2023

Biomimetic nanocarriers fuse with cell membranes to deliver drugs

In drug delivery, the therapeutic behavior of the nanocarriers is limited by the "foreign" character of their surface.

12 Jul 2023

New atlas offers a way to identify the deep mechanisms of cancer

An atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center.

29 Jun 2023

New nanoparticle could improve the delivery of mRNA-based vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

28 Jun 2023

Disorientating the malaria parasite to prevent its replication and transmission

With almost 250 million cases a year, 621,000 of them fatal, malaria remains a major public health problem, particularly in sub-Saharan Africa.

16 Jun 2023

Heat-damaged DNA in food may contribute to genetic risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

13 Jun 2023

Thyrotropin-releasing hormone neurons play a key role in the response to fasting and weight loss

Regulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypothalamus (the region of the brain that controls the involuntary nervous system) has been identified as a direct regulator of thyrotropin (a hormone secreted by the pituitary gland that regulates the production of thyroid hormones).

12 Jun 2023

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Researchers described a novel strategy for controlling severe acute respiratory syndrome coronavirus 2.

5 Jun 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

Small Molecules News and Research

Researchers uncover the biology behind insulin production

USC study reveals key details about how cancer cells metastasize

Arrayjet announces collaboration with Chemspace to augment its small molecule microarray services for drug discovery

Eternal youth? Chemical cocktails prove effective in cell age reversal

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Researchers develop a chemical approach to reverse aging

Scientists identify signal essential for blood-brain barrier formation

Biomimetic nanocarriers fuse with cell membranes to deliver drugs

New atlas offers a way to identify the deep mechanisms of cancer

New nanoparticle could improve the delivery of mRNA-based vaccines

Disorientating the malaria parasite to prevent its replication and transmission

Heat-damaged DNA in food may contribute to genetic risks

Thyrotropin-releasing hormone neurons play a key role in the response to fasting and weight loss

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Scientists study the structure and function of a transporter involved in cancer, immunity

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Specially designed capsule gives a fuller picture of normal digestion in healthy people

Mount Sinai researchers identify a new therapeutic target for MS and other brain disorders

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

New approach addresses the challenge of directly connecting genetic variants to human traits, health

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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