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Crick researchers find promising target for new tuberculosis drugs

Crick researchers find promising target for new tuberculosis drugs

Scientists led by Dr Luiz Pedro Carvalho at the Francis Crick Institute in London have found a promising new target in the search for new tuberculosis drugs. In the process, they say they've proven the strengths of a new research technique called metabolomics. [More]
Scientists begin research work at new £650 million Francis Crick Institute building

Scientists begin research work at new £650 million Francis Crick Institute building

The first scientists have moved into the new £650 million Francis Crick Institute building in London and are starting work in their purpose-built labs. [More]
New test developed by Loughborough University may offer one-stop diagnosis for asthma

New test developed by Loughborough University may offer one-stop diagnosis for asthma

A new test which can diagnose asthma from a patient's saliva has been developed by Loughborough University. [More]
Research seeks to improve nutritional and milling quality of new oat varieties

Research seeks to improve nutritional and milling quality of new oat varieties

Most of the oats American milling companies use comes from Canada—that's something South Dakota State University oats breeder Melanie Caffé-Treml wants to change. Her research seeks to increase the quality of locally-grown oats. [More]
Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA synthesis at hard-to-replicate sites and consequently suppressing DNA damage. The findings are published in PLOS Genetics. [More]
Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

In a novel controlled clinical trial, participants in a six-day Ayurvedic-based well-being program that featured a vegetarian diet, meditation, yoga and massages experienced measurable decreases in a set of blood-based metabolites associated with inflammation, cardiovascular disease risk and cholesterol regulation. [More]
Experts develop urine-based method to diagnose conditions in newborn babies

Experts develop urine-based method to diagnose conditions in newborn babies

Experts from the V. I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology and the Moscow Institute of Physics and Technology have devised a method that uses the urinary proteome to diagnose conditions in newborn babies. [More]
IWGAV establishes strategic recommendations for validating antibody specificity

IWGAV establishes strategic recommendations for validating antibody specificity

The International Working Group on Antibody Validation, an independent group of international scientists with diverse research interests in the field of protein biology, today announced the publication of initial strategies developed to address a critical unmet need for antibody specificity, functionality and reproducibility in the September online issue of Nature Methods. [More]
Six NIH-funded projects aim to identify biological factors that affect neural regeneration

Six NIH-funded projects aim to identify biological factors that affect neural regeneration

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. [More]
Studying mutant peptides may help detect weaknesses in tumor cells

Studying mutant peptides may help detect weaknesses in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing. [More]
Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth. [More]
New study finds contamination events near fracking gas drilling sites result of operational inefficiencies

New study finds contamination events near fracking gas drilling sites result of operational inefficiencies

Chemists at the University of Texas at Arlington have published a new study that indicates that highly variable contamination events registered in and around unconventional oil and gas developments are the result of operational inefficiencies and not inherent to the extraction process itself. [More]
Hitchhiking of drugs on incorrect targets can cause adverse side effects

Hitchhiking of drugs on incorrect targets can cause adverse side effects

It probably isn't surprising to read that pharmaceutical drugs don't always do what they're supposed to. Adverse side effects are a well-known phenomenon and something many of us will have experienced when taking medicines. [More]
Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Supplementing with soluble corn fiber at two critical times in a woman's life - adolescence and post-menopause - can help build and retain calcium in bone, according to new research from Purdue University. [More]
Researchers find reason behind epidemiological success of Russian tuberculosis strains

Researchers find reason behind epidemiological success of Russian tuberculosis strains

Researchers from the Federal Research and Clinical Centre of Physical-Chemical Medicine, and staff from MIPT's Systems Biology Laboratory, the Research Institute of Phthisiopulmonology and the St. Petersburg Pasteur Institute, conducted a large-scale analysis of the proteins and genomes of mycobacterium tuberculosis strains that are common in Russia and countries of the former Soviet Union and found features that provide a possible explanation for their epidemiological success. [More]

Researchers uncover new preventative way to battle against Ascaris roundworm infection

Scientists working out of Trinity College Dublin, Maynooth University, and Queen Mary University of London have unearthed a potential new preventative option to combat Ascaris roundworm infection. [More]
Health Pioneers BetterYou say it’s best to your vitamin D level

Health Pioneers BetterYou say it’s best to your vitamin D level

Recent vitamin D guidance by Public Health England has once again highlighted the UK-wide issue of vitamin D deficiency, but how do you know if you are one of the estimated 10 million people with low vitamin D levels? A simple home test can put your mind at rest, say health pioneers BetterYou. [More]
Study finds high rate of misuse of seizure and pain drug

Study finds high rate of misuse of seizure and pain drug

With increasing public attention to overdose deaths and misuse of prescription medications in the United States, researchers today presented the results of a new study looking at abuse and misuse of gabapentin, a medication used to treat seizures and relieve nerve pain often associated with shingles. [More]
Researchers develop new hybrid method to study HIV protein involved in disease progression

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus. [More]
New biochip test helps identify individuals at increased risk of Alzheimer's disease

New biochip test helps identify individuals at increased risk of Alzheimer's disease

Researchers today unveiled results from a new blood test to help identify which patients are at an elevated risk of Alzheimer's disease. [More]
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