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Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

Immune-evading Mycobacterium tuberculosis prevents inflammatory responses by hijacking the host’s ubiquitin

A new study discussed the findings of Chai et al., which revealed that triple specificity protein phosphatase (ptpB) secreted by Mycobacterium tuberculosis inhibits pyroptosis and the release of cytokines by macrophages, allowing M. tuberculosis to invade the immune system.

19 Dec 2022

Novel experimental system traces the development and longevity of plasma cells

Just as a fire department mobilizes in response to a reported fire, specialized immune cells in the body mobilize in response to the introduction of foreign substances known as antigens.

15 Dec 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Scientists develop preclinical model of scrub typhus disease

Scientists have developed an animal model of scrub typhus using outbred CD-1 mice. Using the model, they have characterized host susceptibility to the causative pathogen, disease pathogenesis, and immune responses. The study has been published in the journal PLOS Neglected Tropical Diseases.

27 Nov 2022

Kiwira virus: a new bat-borne hantavirus detected in Africa

Researchers discover a novel hantavirus called the Kiwira virus.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

Why we should all eat Kimchi and other Korean fermented foods

A recent study reviews various traditional Korean fermented foods for their various health benefits.

20 Nov 2022

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

In a recent study posted to the bioRxiv* preprint server, researchers evaluated responses of natural killer (NK) lymphocytes to VACV (vaccinia virus) infections in vivo.

16 Nov 2022

What is the role of macrophage origin, function, and heterogeneity in health and disease?

In a new study, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages.

14 Nov 2022

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes.

10 Nov 2022

Pioneering research identifies a promising treatment approach for myelofibrosis

Pioneering research into the chronic inflammation often seen in certain blood cancers has identified a promising treatment approach for myelofibrosis, a potentially deadly bone marrow cancer.

9 Nov 2022

Fermented dairy products can improve gut mucosal immunity

In a recent study published in the journal Immunology Letters, researchers assessed the role of fermented dairy products and dairy starters in modulating gut mucosal immunity.

3 Nov 2022

Avian influenza virus introduced from Europe to North America through Iceland

A new study indicated that Iceland was the stepping stone for the translocation of the highly pathogenic avian influenza virus (HPAIV) between North America and Europe.

25 Oct 2022

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

17 Oct 2022

Spleen News and Research

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Immune-evading Mycobacterium tuberculosis prevents inflammatory responses by hijacking the host’s ubiquitin

Novel experimental system traces the development and longevity of plasma cells

SARS-CoV-2 can cause hyperglycemia in cats

Scientists develop preclinical model of scrub typhus disease

Kiwira virus: a new bat-borne hantavirus detected in Africa

Study suggests bats are an underrecognized arenavirus reservoir

Why we should all eat Kimchi and other Korean fermented foods

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

What is the role of macrophage origin, function, and heterogeneity in health and disease?

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

Pioneering research identifies a promising treatment approach for myelofibrosis

Fermented dairy products can improve gut mucosal immunity

Avian influenza virus introduced from Europe to North America through Iceland

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

Did the diagnosis and management of Hodgkin lymphoma differ during the SARS-CoV-2 pandemic?

Study provides new insights into the origin and development of B cells

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

UAB study finds distinct kidney resident macrophage subpopulations located in spatially discrete microenvironments

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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