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PDL revises revenue guidance for second quarter 2011 to $122M

PDL BioPharma, Inc. (PDL) today revised its guidance for the second quarter ending June 30, 2011, to approximately $122 million, as compared with actual results of $120 million for the second quarter of 2010, an anticipated one percent year-over-year increase.

9 Jun 2011

Yikes! 5,085 kilojoules and 80.5 grams of fat in one burger

After the naming of a Hungry Jack's burger as the unhealthiest in the nation, all state governments are planning to introduce legislation requiring fast food outlets to list the energy content on their menus.

9 Jun 2011

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

Novartis announced new data today showing a significant improvement in both recurrence-free survival and overall survival for patients taking Gleevec® (imatinib mesylate)* tablets for three years after surgery to remove KIT (CD117)-positive gastrointestinal stromal tumors (KIT+ GIST) compared to one year of treatment. These data will be presented at the 47th American Society of Clinical Oncology (ASCO) plenary session on Sunday, June 5.

6 Jun 2011

New guideline on bariatric surgery

The treatment of obesity still needs improvement. In the current issue of Deutsches Ärzteblatt International, Norbert Runkel and colleagues present a new, interdisciplinary S3 guideline entitled "Bariatric Surgery".

6 Jun 2011

Genentech's Avastin, chemotherapy Phase III combination study data on ovarian cancer presented at ASCO

Genentech, a member of the Roche Group, today announced results from OCEANS, a Phase III study evaluating Avastin (bevacizumab) in combination with chemotherapy followed by the continued use of Avastin alone in women with previously treated (recurrent) platinum-sensitive ovarian cancer.

6 Jun 2011

Sanofi's semuloparin Phase III study data against venous thromboembolism presented at ASCO 2011

Sanofi US announced today results of the pivotal SAVE-ONCO study which demonstrated that, in cancer patients initiating a chemotherapy regimen, investigational semuloparin significantly reduced the risk of the composite of symptomatic-deep vein thromboembolism (DVT), non-fatal pulmonary embolism (PE) or venous thromboembolism (VTE)-related death by 64%, meeting the study primary endpoint.

4 Jun 2011

Geophagy protects stomach against toxins, parasites and pathogens

Most of us never considered eating the mud pies we made as kids, but for many people all over the world, dining on dirt is nothing out of the ordinary. Now an extensive meta-analysis forthcoming in the June issue of The Quarterly Review of Biology helps explain why.

3 Jun 2011

Innovations in diagnosis and treatment for esophageal cancer

In recent years, the number of cases of adenocarcinoma of the esophagus (or gullet) has been on the rise. At the same time, however, new ways of treatment are improving the outlook for patients. In the current issue of Deutsches Ärzteblatt International, Angelika Behrens and her working group report on innovations in diagnosis and treatment.

27 May 2011

Research sheds light on how painkillers could prevent or slow down cancer growth

CANCER RESEARCH UK scientists have shed light on how a common class of painkillers - which includes ibuprofen - may interact with a key protein that fuels the growth of many different types of cancer, according to a study published in the journal Chemical Communications today.

27 May 2011

Coronary artery disease is a leading cause of death in U.S. women

It's a silent killer, most women don't even know they have it. It's often thought of as a man's disease and may not receive as much attention as other illnesses, but coronary artery disease (CAD) is the leading cause of death in women in the U.S. It is so common that if you combine the number of women who die from the next five leading causes of death it would equal the number of women who die from CAD.

26 May 2011

Eating with a larger fork leads to less food consumption

Researchers from the University of Utah have found when eating at a restaurant, diners who wish to eat less food should eat with a larger fork.

25 May 2011

Transarterial embolization an effective alternative to endoscopy for acute peptic ulcer bleeding

Researchers from China report that in patients with peptic ulcer bleeding in whom endoscopy failed to control the bleeding, transarterial embolization is a safe procedure which reduces the need for surgery without increasing overall mortality and is associated with few complications.

24 May 2011

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders, suggests a study led by Vanderbilt University Medical Center researcher Fang Yan, M.D., Ph.D.

24 May 2011

H. pylori infection could play a role in Parkinson's disease development

The stomach bacteria responsible for ulcers could also play a role in the development of Parkinson's disease according to research presented today at the 111th General Meeting of the American Society for Microbiology.

23 May 2011

FDA approves Sutent for patients with progressive neuroendocrine cancerous tumors in pancreas

The U.S. Food and Drug Administration today approved Sutent (sunitinib) to treat patients with progressive neuroendocrine cancerous tumors located in the pancreas that cannot be removed by surgery or that have spread to other parts of the body (metastatic).

21 May 2011

Two genes linked to worst cases of esophageal cancer

University of Rochester Medical Center researchers have pinpointed two genes that are amplified in the worst cases of esophageal cancer, providing data to support a new investigational treatment that targets those same genes.

19 May 2011

New data on personalized approaches for skin, ovarian and lung cancer to be presented at ASCO meeting

Genentech, a member of the Roche Group, today announced that data showing new personalized approaches for people with skin and lung cancer, plus new data with Avastin in ovarian cancer, will be presented at the 47th Annual Meeting of the American Society of Clinical Oncology.

18 May 2011

Perrigo's ANDA for generic Zantac 150 receives FDA final approval to treat heartburn

Perrigo Company today announced that it has received final approval from the U.S. Food and Drug Administration for its abbreviated new drug application for over-the-counter Ranitidine 150, a generic version of Zantac 150.

17 May 2011

New genome-wide study identifies causes of serious childhood immune disorder

A new genomics study, led by the Center for Applied Genomics at The Children's Hospital of Philadelphia, sets the stage for the first predictive diagnostic test in a serious immunodeficiency disease in children. If the disorder, common variable immunodeficiency disease, can be diagnosed early, children may receive life-saving treatments before the disease can progress.

12 May 2011

Multiband mucosectomy safe and effective for treating Barrett's esophagus

An increasingly popular technique for removing lesions associated with Barrett's esophagus has been deemed a safe and effective treatment option in a study of more than 1,000 resections published this month in the European journal Endoscopy.

10 May 2011

Stomach News and Research

PDL revises revenue guidance for second quarter 2011 to $122M

Yikes! 5,085 kilojoules and 80.5 grams of fat in one burger

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

New guideline on bariatric surgery

Genentech's Avastin, chemotherapy Phase III combination study data on ovarian cancer presented at ASCO

Sanofi's semuloparin Phase III study data against venous thromboembolism presented at ASCO 2011

Geophagy protects stomach against toxins, parasites and pathogens

Innovations in diagnosis and treatment for esophageal cancer

Research sheds light on how painkillers could prevent or slow down cancer growth

Coronary artery disease is a leading cause of death in U.S. women

Eating with a larger fork leads to less food consumption

Transarterial embolization an effective alternative to endoscopy for acute peptic ulcer bleeding

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

H. pylori infection could play a role in Parkinson's disease development

FDA approves Sutent for patients with progressive neuroendocrine cancerous tumors in pancreas

Two genes linked to worst cases of esophageal cancer

New data on personalized approaches for skin, ovarian and lung cancer to be presented at ASCO meeting

Perrigo's ANDA for generic Zantac 150 receives FDA final approval to treat heartburn

New genome-wide study identifies causes of serious childhood immune disorder

Multiband mucosectomy safe and effective for treating Barrett's esophagus

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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