Systemic Lupus Erythematosus News and Research

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Systemic lupus erythematosus (SLE) is the form of the disease that most people are referring to when they say "lupus." The word "systemic" means the disease can affect many parts of the body. The symptoms of SLE may be mild or serious. Although SLE usually first affects people between the ages of 15 and 45 years, it can occur in childhood or later in life as well.

UH expert in lupus reports two new discoveries

Two separate findings by a University of Houston nationally recognized expert in systemic lupus erythematosus (SLE or lupus), a chronic autoimmune disease that affects multiple organs including the kidneys, skin, joints and heart, are being reported in scientific and medical journals.

2 Jun 2022

Report highlights the need for an office to support autoimmune disease research across NIH institutes

While the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimmune diseases is impressive, a strategic plan and a well-funded office to support the coordination of all autoimmune disease research across NIH institutes and centers are needed, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

10 May 2022

Elevated and sustained autoantibodies following COVID-19

A new study demonstrated that autoantibody levels rise following acute SARS-CoV-2 infection and remain to be elevated for about six months.

10 May 2022

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched an early-stage clinical trial to evaluate an investigational preventative vaccine for Epstein-Barr virus (EBV).

6 May 2022

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

NYU Langone Health is joining a new National Institutes of Health (NIH)-sponsored program called Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases (AMP AIM) as a leading center to discover new targets for therapy in these diseases.

30 Mar 2022

Research finds link between long-term exposure to air pollution and autoimmune disease risk

Long term exposure to air pollution is linked to a heightened risk of autoimmune disease, particularly rheumatoid arthritis, connective tissue and inflammatory bowel diseases, finds research published online in the open access journal RMD Open.

16 Mar 2022

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

The American College of Rheumatology and the American Association of Hip and Knee Surgeons released a summary of their updated guideline for the Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty.

28 Feb 2022

EULAR develops new recommendations for cardiovascular risk management

EULAR, the European Alliance of Associations for Rheumatology, has developed new recommendations for CVR management in people with gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), and antiphospholipid syndrome (APS).

23 Feb 2022

The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

A survey demonstrated that patients with systemic autoimmune rheumatic diseases commonly experience augmented disease severity and disrupted treatment regimens of disease-modifying antirheumatic drugs after acute COVID-19 course.

11 Feb 2022

New, more accurate tool to measure the progress of lupus in patients

A new paper in Rheumatology, published by Oxford University Press, indicates that researchers have developed a new, easier, and more accurate tool to measure the progress of lupus in patients.

25 Jan 2022

Transplant recipients benefit from a COVID-19 vaccine booster

A new preprint research paper posted to the medRxiv* server describes the reduction in humoral immunity in SOTR following vaccination, as well as the improvement with an additional dose of the vaccine.

4 Jan 2022

Impact of mRNA-1273 vaccination during early pregnancy

Researchers from Yale University School of Medicine found that vaccination during the first trimester does not produce congenital disabilities or size abnormalities.

10 Dec 2021

The autoantibody profile in COVID-19 patients with MIS-C

A new study assessed the presence of autoantibodies against autoantigens associated with known autoimmune diseases in patients with COVID-19.

10 Nov 2021

Study looks at how lupus genetics intersects with COVID-19

The study “Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19” was recently published on the preprint medRxiv* server.

8 Nov 2021

Study finds persistent racial gaps in renal complications for children with juvenile lupus

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that while hospitalized children with juvenile lupus have fewer adverse kidney outcomes overall, significant racial gaps for developing these complications persist and do not seem to be narrowing.

2 Nov 2021

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that heart rate monitoring is a feasible, accurate tool to check for heart rhythm abnormalities in the fetuses of pregnant women with anti-Ro/SSA antibodies.

2 Nov 2021

Black patients with systemic sclerosis may experience poorer outcomes more often than others

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that Black people living with systemic sclerosis may have more severe disease and worse prognosis than patients in other racial or ethnic groups, and these worrying disparities may be driven by several socioeconomic factors.

2 Nov 2021

Systemic Lupus Erythematosus News and Research

UH expert in lupus reports two new discoveries

Report highlights the need for an office to support autoimmune disease research across NIH institutes

Elevated and sustained autoantibodies following COVID-19

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

Research finds link between long-term exposure to air pollution and autoimmune disease risk

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

EULAR develops new recommendations for cardiovascular risk management

The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

New, more accurate tool to measure the progress of lupus in patients

Transplant recipients benefit from a COVID-19 vaccine booster

Impact of mRNA-1273 vaccination during early pregnancy

The autoantibody profile in COVID-19 patients with MIS-C

Study looks at how lupus genetics intersects with COVID-19

Study finds persistent racial gaps in renal complications for children with juvenile lupus

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

Black patients with systemic sclerosis may experience poorer outcomes more often than others

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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