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Tacrolimus is a drug used to help reduce the risk of rejection by the body of organ and bone marrow transplants.

Astellas receives exclusive rights to develop and commercialize linaclotide compound in Asia

10. November 2009 02:11
Ironwood Pharmaceuticals, Inc. and Astellas Pharma Inc. today announced that they have entered into an agreement providing Astellas exclusive rights to develop and commercialize the investigational compound linaclotide in Japan, Indonesia, Korea, the Philippines, Taiwan, and Thailand. [More]

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Interim data from Bristol-Myers Squibb's BARACLUDE study for chronic hepatitis B patients

2. November 2009 04:03
Bristol-Myers Squibb today announced 48-week data from an ongoing study (ETV-048) of chronic hepatitis B patients with decompensated cirrhosis, in which BARACLUDE demonstrated greater viral suppression compared to adefovir. The new BARACLUDE data were presented today at the 60th Annual Meeting of the American Association for the Study of Liver Diseases. [More]

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New data on KAPIDEX for nighttime heartburn in adults with non-erosive GERD presented at the 2009 ACG

27. October 2009 05:29
New data being presented at the American College of Gastroenterology (ACG) 2009 Annual Scientific Meeting in San Diego showed that treatment with KAPIDEX(TM) (dexlansoprazole) delayed release capsules over a four-week period resulted in a statistically significant greater percentage of nights without heartburn in subjects with non-erosive gastroesophageal reflux disease (GERD), compared to placebo (p<0.001). [More]

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Survival rates for multivisceral transplants increase with new treatment strategies

6. October 2009 04:26
Data from the largest single-center experience of adult and pediatric intestinal and multivisceral transplantation show that survival rates have improved with the advent of innovative surgical techniques, novel immunosuppressive protocols and better post-operative management, said researchers at the Thomas E. Starzl Transplantation Institute in a study published in the October issue of Annals of Surgery. [More]

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Results from Phase 2 clinical study of LCP-Tacro tablets in stable liver transplant patients announced

30. September 2009 03:06
LifeCycle Pharma A/S today announced positive results from a completed 12 month extension phase of the Phase 2 clinical study of LCP-Tacro tablets in stable liver transplant patients. [More]

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Research study indicates that liver regeneration could affect the metabolism of tacrolimus in LDLT

27. August 2009 02:27
Several studies have shown that living donor liver transplant (LDLT) recipients required smaller doses of tacrolimus compared with deceased donor liver transplant (DDLT) patients, which indicated that liver regeneration could affect the metabolism of tacrolimus in LDLT. [More]

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The extremes of BMI a cause for concern in liver transplantation

4. August 2009 03:31
A recent study by doctors at the University of Washington explained that patients who are significantly underweight or very severely obese prior to liver transplantation are at increased risk of death following transplantation surgery. [More]

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Discovery of new angiogenesis protein - possible cancer drug target

9. June 2009 15:49
To grow and spread, tumors need new blood vessels, a process called angiogenesis. One growth factor that causes angiogenesis has been identified - vascular endothelial growth factor or VEGF - and drugs to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long term. Thus new growth factors need to be identified to aid in developing the next generation of angiogenesis inhibitors. [More]

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Emerging therapies could ease symptoms of Atopic dermatitis

5. March 2009 20:05
Atopic dermatitis, the common, chronic, inflammatory skin disease marked by red, itchy rashes, has been increasing in prevalence over the past two decades and affects a disproportionate number of children. [More]

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Revolutionary technique that could reduce lifelong drugs for transplant patients shows promising findings

5. August 2008 05:40
Researchers have developed a ground-breaking procedure that could avoid the need for transplant patients to spend the rest of their lives taking a cocktail of drugs to stop their system from rejecting their new organ, according to a series of papers in the August issue of Transplant International. [More]

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Cellcept immunosuppressant further linked to birth defects

7. February 2008 12:20
A new study documents malformations seen in an infant born to a kidney transplant recipient who had taken mycophenolate mofetil (MMF), a widely used immunosuppressant available commercially as Cellcept. [More]

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Mild chemo before stem cell transplant causes long-term remission of follicular lymphoma

10. December 2007 22:09
Treating relapsed follicular lymphoma patients with a milder chemotherapy regimen before they receive a blood stem cell transplant from a donor resulted in long-term complete remission for 45 of 47 patients in a clinical trial, researchers at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology. [More]

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Renal transplantation in 1-5 year olds

26. April 2007 05:35
Garcia, et al reported their experience with renal transplantation in 38 children (40 transplant), ages 1-5 years over a 16 year period. [More]

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German scientists synthesize new compound that reduces stroke damage

16. May 2006 07:17
A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms. [More]

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Topical therapies show promise for Psoriasis

6. March 2006 04:11
Psoriasis, a chronic skin condition characterized by thick, red, scaly patches that itch and bleed, not only makes the activities of daily life difficult, but also can affect a person's emotional well being. [More]

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