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Researchers analyze outcomes in patients with primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is a type of cancer that develops in the brain and or spinal cord.

7 Dec 2020

Preliminary analysis of photon therapy treatment group 1 shows no significant differences between arms

A preliminary analysis of photon therapy treatment group 1 from the phase II NRG Oncology clinical trial NRG-BN001 indicates that there is no statistically significant overall survival (OS) or toxicity differences between dose-intensification radiation therapy (DI-RT) using intensity-modulated radiation therapy (IMRT) and standard-dose radiation therapy (SD-RT) with temozolomide treatments for patients with newly diagnosed glioblastoma (GBM).

27 Oct 2020

FDA grants rare disease designations to investigational brain tumor drug

The U.S. Food and Drug Administration has awarded Rare Pediatric Disease Designation (RPDD) for diffuse intrinsic pontine glioma (DIPG) and Orphan Drug Designation for treatment of malignant glioma to OKN-007, an investigational drug discovered at the Oklahoma Medical Research Foundation and being developed by Oblato, Inc.

2 Sep 2020

Researchers develop novel approach for utilizing 4D-printing of arrays to accelerate drug testing

Investigators at Rutgers Cancer Institute of New Jersey have developed a novel approach for utilizing 4-dimensional (4D) printing of arrays that transform from cell-culture inserts into histological cassettes that hold patient tissue samples for rapid programmable drug testing.

12 Aug 2020

CNIO and HKUST researchers identify how some gliomas acquire chemoresistance

A team led by Massimo Squatrito, Head of the Seve Ballesteros Foundation Brain Tumour Group at the Spanish National Cancer Research Centre, have made important findings of how some gliomas can acquire chemoresistance.

4 Aug 2020

UVA scientists identify oncogene responsible for deadliest brain tumor

Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor.

14 Jul 2020

Researchers uncover a potentially promising strategy to target brain tumors

Gliomas with mutations in what are called the isocitrate dehydrogenase (IDH) genes are the most common brain tumors diagnosed in younger adults aged 18 to 45 years.

30 Jun 2020

Antimalarial drug shows promise as potential therapy for aggressive brain cancer

Glioblastoma multiforme is an aggressive form of cancer in the brain that is typically fatal. But new findings by VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers could help increase the effectiveness of the most common current treatments with the addition of lumefantrine, an FDA-approved drug used to treat malaria.

26 May 2020

Combination therapy boosts the immune system's appetite for cancer

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

Removing 'non-contrast enhancing tumor' may boost survival of glioblastoma patients

Survival may more than double for adults with glioblastoma, the most common and deadly type of brain tumor, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.

10 Feb 2020

Expanded Medication Assistance Program increases access to vital cancer therapies

The Medical Assistance Program at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has helped more than 30,000 patients gain access to vital medications valued at more than $500 million, and a new program expansion will further increase access to vital cancer therapies for patients with the greatest financial need.

4 Feb 2020

Improved microfluidic brain chip can assess the effectiveness of cancer drugs in record time

The Akay Lab biomedical research team at the University of Houston is reporting an improvement on a microfluidic brain cancer chip previously developed in their lab.

17 Jan 2020

Researchers identify new mechanism associated with p53 mutation

More than half of cancer cases worldwide are associated with genetic mutations in p53, the protein responsible for protecting DNA from changes that can lead to cancer.

9 Jan 2020

Scientists use novel technology for opening blood-brain barrier with implantable ultrasound

One of most potent drugs for treatment of glioblastoma, the most deadly type of brain tumor, can't be used in patients because of two problems. First, it can't reach its target because it's blocked by the blood-brain barrier, a microscopic structure that protects the brain from toxins in the blood. And the conventional formulation for this drug is toxic to the brain.

12 Dec 2019

Important biomarker may help in determining prognosis of brain cancer patients

A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent study published by a student researcher at the University of Cincinnati.

9 Dec 2019

Researchers develop new strategy for treating the most aggressive type of brain cancer

Researchers from the University of São Paulo in Brazil have developed a strategy for treating the most aggressive type of brain cancer in adults that combines a photoactive molecule and a chemotherapeutic agent - both encapsulated in protein-lipid nanoparticles.

27 Nov 2019

Temozolomide News and Research

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Preliminary analysis of photon therapy treatment group 1 shows no significant differences between arms

FDA grants rare disease designations to investigational brain tumor drug

Researchers develop novel approach for utilizing 4D-printing of arrays to accelerate drug testing

CNIO and HKUST researchers identify how some gliomas acquire chemoresistance

UVA scientists identify oncogene responsible for deadliest brain tumor

Researchers uncover a potentially promising strategy to target brain tumors

Antimalarial drug shows promise as potential therapy for aggressive brain cancer

Combination therapy boosts the immune system's appetite for cancer

Removing 'non-contrast enhancing tumor' may boost survival of glioblastoma patients

Expanded Medication Assistance Program increases access to vital cancer therapies

Improved microfluidic brain chip can assess the effectiveness of cancer drugs in record time

Researchers identify new mechanism associated with p53 mutation

Scientists use novel technology for opening blood-brain barrier with implantable ultrasound

Important biomarker may help in determining prognosis of brain cancer patients

Researchers develop new strategy for treating the most aggressive type of brain cancer

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

Chemotherapy drugs delivered using biodegradable paste can prolong survival in brain cancer

New treatment method for glioblastoma shows indication of benefit

Promising new approaches in the fight against brain metastasis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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