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Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Cervical cancer is among the most common malignancies affecting women worldwide. In 2020 alone, approximately 600,000 women were diagnosed with this disease, and over 314,000 died from it.

5 Mar 2024

Exonate first-in-class eye drop Phase Ib/IIa trial data demonstrate safety and biological activity in treatment of diabetic retinopathy and diabetic macular oedema

EXN407 is the first topical SRPK1 inhibitor to demonstrate both safety and signals of biological response as monotherapy for these indications.

5 Mar 2024

Harnessing repetitive DNA for early cancer detection

People with cancer have different amounts of a type of repetitive DNA -; called Alu elements -; than people without cancer.

4 Mar 2024

Nanoparticle therapy offers hope for aortic aneurysm treatment

Aortic aneurysms are bulges in the aorta, the largest blood vessel that carries oxygen-rich blood from the heart to the rest of the body.

4 Mar 2024

Microbial signatures linked to immunotherapy response across cancers

The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynecological cancers, biliary tract cancers and melanoma.

1 Mar 2024

Penn engineers develop targeted lung delivery system using lipid nanoparticles

Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the miniscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel treatments for pulmonary diseases like cystic fibrosis.

1 Mar 2024

SickKids study offers new path for pediatric rare disease clinical trials

Using a novel methodology, researchers at The Hospital for Sick Children (SickKids) are the first in pediatric research to use data from an international real-world cohort to overcome the barriers associated with conducting randomized clinical trials in children with rare diseases.

29 Feb 2024

Uncovering the role of mucus in pancreatic cancer transformation

Knowing exactly what's inside a tumor can maximize our ability to fight cancer. But that knowledge doesn't come easy. Tumors are clusters of constantly changing cancer cells.

28 Feb 2024

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.

28 Feb 2024

Anti-cancer drug shows promise in treating brain injuries after stroke

A study by the Institut de Neurociències of the UAB (INc-UAB) demonstrates in animal models the benefits of vorinostat after having suffered a stroke.

28 Feb 2024

AGA publishes white paper on the future of IBD care in the United States

Today, the American Gastroenterological Association (AGA) published a white paper on the future of inflammatory bowel disease (IBD) care in the United States.

28 Feb 2024

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

28 Feb 2024

Using machine learning to identify key predictors of mortality in dementia patients

Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients.

28 Feb 2024

Bariatric surgery outperforms medical management in long-term diabetes control

People with type 2 diabetes who underwent bariatric surgery achieved much better long-term blood glucose control compared to people who received medical management plus lifestyle interventions, according to a new study published in JAMA, or Journal of the American Medical Association, and funded by the National institute of Diabetes, Digestive and Kidney Diseases, part of The National Institutes of Health.

27 Feb 2024

UMSOM wins $3.5 million BARDA contract to develop animals models for radiation research

University of Maryland School of Medicine Dean Mark T. Gladwin, MD, announced today that UMSOM faculty scientists have been selected as key contractors by the Biomedical Advanced Research and Development Authority (BARDA), for the federal agency's Radiation Nuclear Animal Model Development program.

26 Feb 2024

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Boston College Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to study viral insulins and mechanisms related to IGF-1 receptor protein inhibition and its potential applications in cancer treatment.

26 Feb 2024

Therapeutics News and Research

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Exonate first-in-class eye drop Phase Ib/IIa trial data demonstrate safety and biological activity in treatment of diabetic retinopathy and diabetic macular oedema

Harnessing repetitive DNA for early cancer detection

Nanoparticle therapy offers hope for aortic aneurysm treatment

Microbial signatures linked to immunotherapy response across cancers

Penn engineers develop targeted lung delivery system using lipid nanoparticles

SickKids study offers new path for pediatric rare disease clinical trials

Uncovering the role of mucus in pancreatic cancer transformation

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

Anti-cancer drug shows promise in treating brain injuries after stroke

AGA publishes white paper on the future of IBD care in the United States

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

Using machine learning to identify key predictors of mortality in dementia patients

Bariatric surgery outperforms medical management in long-term diabetes control

UMSOM wins $3.5 million BARDA contract to develop animals models for radiation research

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Using deep brain stimulation to map dysfunctional brain circuits linked to four disorders

Yale School of Medicine secures $575,000 grant for Long COVID research

Automated insulin delivery systems: Advancements and future prospects

Off-the-shelf cancer vaccine shows promising results in patients with KRAS-mutated tumors

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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