Therapeutics News and Research

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Off-the-shelf cancer vaccine shows promising results in patients with KRAS-mutated tumors

Samara Rahman, 74, considers herself lucky. She gets to take walks on the beach, go swimming and ride her bike -; all things that were taken from her when she was diagnosed with pancreatic cancer in November of 2022.

22 Feb 2024

Mapping the human dysfunctome with deep brain stimulation

A new study led by investigators from Mass General Brigham demonstrated the use of deep brain stimulation (DBS) to map a 'human dysfunctome' -; a collection of dysfunctional brain circuits associated with different disorders.

22 Feb 2024

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

22 Feb 2024

New immunotherapy target activin receptor 1C shows promise against cancer

Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients' immune systems fight back against cancer, according to a study by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Feb 2024

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

The University of Texas MD Anderson Cancer Center today announced it has acquired certain assets from Bellicum Pharmaceuticals, Inc. related to the CaspaCIDe switch platform and the GoCAR platform.

22 Feb 2024

Simple blood test to detect Alzheimer's disease may replace more invasive diagnostic methods

A simple blood test to diagnose Alzheimer's disease soon may replace more invasive and expensive screening methods such as spinal taps and brain scans.

22 Feb 2024

Selkirk Pharma announces new APS qualified facility with advanced fill/finish capacity in Spokane, WA

Selkirk Pharma, Inc., a privately held U.S. pharmaceutical manufacturer specializing in the fill and finish of injectable drugs, including vaccines and biological therapeutics, today announced the Aseptic Process Simulation (APS) qualification of its sterile manufacturing facility and newly available fill/finish capacity.

From Selkirk Pharma 22 Feb 2024

Novel treatment for polycythemia vera shows promise in clinical trial

A novel treatment for polycythemia vera, a potentially fatal blood cancer, demonstrated the ability to control overproduction of red blood cells, the hallmark of this malignancy and many of its debilitating symptoms in a multi-center clinical trial led by the Icahn School of Medicine at Mount Sinai.

21 Feb 2024

Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

UT Health Science Center researchers Gabor Tigyi, MD, PhD, Harriet Van Vleet Endowment Professor in Basic Oncology Research, Junming Yue, PhD, associate professor in the Department of Pathology, Sue Chin Lee, PhD, in the Department of Physiology, and David Schwartz, MD, chair of the Department of Radiation Oncology, are part of a scientific leadership group awarded $20 million from the University of Tennessee-Oak Ridge Innovation Institute in partnership with Oak Ridge National Laboratory and the University of Tennessee, Knoxville, to develop new radiopharmaceutical therapies to treat cancer.

21 Feb 2024

NIH grant boosts research on biofilm dispersal in wound infections

Most chronic wound infections share one thing in common: the presence of biofilms, which are composed of many different microorganisms that congregate as a mass, usually on some type of surface such as a wound bed.

21 Feb 2024

ESMO Congress 2024: Shaping the future of anticancer therapies

The ESMO Targeted Anticancer Therapies Congress 2024 is the annual multi-stakeholder meeting that focuses on the development of novel anticancer therapies and how this can transform the current knowledge and impact clinical care.

21 Feb 2024

Pioneering cell-based treatment for melanoma offered at Siteman Cancer Center

Siteman Cancer Center, based at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, is one of the first centers nationwide to offer a newly approved cell-based immunotherapy that targets melanoma.

20 Feb 2024

Scientists identify new therapeutic approach for combating neurodegenerative diseases

A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases, offering hope of improved treatments for Alzheimer's disease, Parkinson's disease, Vanishing White Matter disease and multiple sclerosis, among others.

20 Feb 2024

Aging alters fibroblasts to promote pancreatic cancer growth

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

20 Feb 2024

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

20 Feb 2024

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year.

20 Feb 2024

Selection, optimization, and validation of genetic tests for 10 common diseases

By analyzing millions of small genetic differences across a person's genome, researchers can calculate a polygenic risk score to estimate someone's lifetime odds of developing a certain disease.

19 Feb 2024

Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

19 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

A Husker research duo was named a first-round winner in a National Institutes of Health competition aimed at generating solutions for delivering genome-editing technology to the cells of people with rare and common diseases.

19 Feb 2024

Therapeutics News and Research

Off-the-shelf cancer vaccine shows promising results in patients with KRAS-mutated tumors

Mapping the human dysfunctome with deep brain stimulation

Natural killer cells lead the charge in cancer treatment innovation

New immunotherapy target activin receptor 1C shows promise against cancer

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

Simple blood test to detect Alzheimer's disease may replace more invasive diagnostic methods

Selkirk Pharma announces new APS qualified facility with advanced fill/finish capacity in Spokane, WA

Novel treatment for polycythemia vera shows promise in clinical trial

Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

NIH grant boosts research on biofilm dispersal in wound infections

ESMO Congress 2024: Shaping the future of anticancer therapies

Pioneering cell-based treatment for melanoma offered at Siteman Cancer Center

Scientists identify new therapeutic approach for combating neurodegenerative diseases

Aging alters fibroblasts to promote pancreatic cancer growth

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Selection, optimization, and validation of genetic tests for 10 common diseases

Study discovers link between a breakdown product from excess niacin and heart disease

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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