Thrombocytopenia News and Research

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Thrombocytopenia is a condition in which there is a lower-than-normal number of platelets in the blood. It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues.

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome.

8 Jun 2023

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Researchers described severe and fatal infections in neonates caused by a new echovirus 11 (E-11) variant in France.

5 Jun 2023

Monovalent COVID-19 booster vaccinations administered in early pregnancy not linked with miscarriage

HealthPartners Institute researchers have published new data in JAMA Network Open that shows monovalent COVID-19 booster vaccinations administered in early pregnancy (before 20 weeks' gestation) were not associated with miscarriage.

19 May 2023

New definitions can specify high-risk comorbidity combinations for older surgical patients

A new way to identify more specific, higher-risk groups of older surgical patients can help in clinical decision-making and accurately comparing the performance of one hospital to another, according to research published in the Journal of the American College of Surgeons.

16 Mar 2023

Anti-heparin antibodies develop in patients with spontaneous heparin-induced thrombocytopenia without heparin exposure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Spontaneous heparin-induced thrombocytopenia is a pro-thrombotic syndrome in which anti-heparin antibodies develop without heparin exposure.

17 Feb 2023

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Researchers examined the factors associated with stroke following coronavirus disease 2019 (COVID-19) vaccination.

13 Feb 2023

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

Results from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free survival (PFS) times in patients with triple-negative breast cancer (TNBC) that has a "BRCA-like" phenotype.

31 Jan 2023

New study evaluates the safety profile of the BNT162b2 vaccine in New Zealand

Researchers determined the association between adverse events of special interest (AESIs) following BNT162b2 vaccination, a coronavirus disease 2019 (COVID-19) vaccine based on the messenger ribonucleic acid (mRNA) technology.

24 Jan 2023

Analysis of adverse events in older US adults after COVID-19 mRNA vaccination

Researchers evaluated adverse events in older adults after mRNA vaccination for COVID-19.

24 Jan 2023

What was the prevalence of adverse events following first and second dose COVID-19 vaccinations in England?

A recent Eurosurveillance study focused on estimating the incidence of a prespecified list of adverse events following the first and second doses of the COVID-19 vaccination.

23 Jan 2023

2022: a year in MIS-C research

In a recent review published in Nature Reviews Rheumatology, researchers reviewed existing data on the multisystem inflammatory syndrome in children (or MIS-C).

11 Jan 2023

Novel T cell receptor therapy shows early promise for treating solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

9 Jan 2023

Novel drug shows early potential in combating multiple myeloma

A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania's Abramson Cancer Center at the 2022 American Society of Hematology Annual Meeting (Abstract 565).

12 Dec 2022

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial, which was conducted globally, including at Georgetown University Medical Center.

12 Dec 2022

Thrombocytopenia News and Research

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Monovalent COVID-19 booster vaccinations administered in early pregnancy not linked with miscarriage

New definitions can specify high-risk comorbidity combinations for older surgical patients

Anti-heparin antibodies develop in patients with spontaneous heparin-induced thrombocytopenia without heparin exposure

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

New study evaluates the safety profile of the BNT162b2 vaccine in New Zealand

Analysis of adverse events in older US adults after COVID-19 mRNA vaccination

What was the prevalence of adverse events following first and second dose COVID-19 vaccinations in England?

2022: a year in MIS-C research

Novel T cell receptor therapy shows early promise for treating solid tumors

Novel drug shows early potential in combating multiple myeloma

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Large COVID vaccination study found that thrombosis and thrombocytopenia are very rare complications

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Comprehensive analysis outlines the potential toxicities of antibody drug conjugates

U.S. COVID-19 vaccine safety surveillance results for the over 65s

Thrombocytopenia may increase the risk of preeclampsia in pregnant women with COVID-19

Study suggests anti-PF4 antibodies may play a role in the severe multiorgan disease manifestations of COVID-19

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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