Thrombus News and Research

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A blood clot or thrombus, is the final product of the blood coagulation step in hemostasis. It is achieved via the aggregation of platelets that form a platelet plug, and the activation of the humoral coagulation system (i.e. clotting factors).

Researchers discover a new switching point that regulates hemostasis and thrombosis

The glycoprotein V of the blood platelets is an important switch point for hemostasis and thrombus formation. This new finding could have great clinical potential.

24 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Youth overweight increases risk for blood clots later in life

Being overweight in childhood and in early adulthood are discrete risk factors for blood clots later in life, a University of Gothenburg study shows.

2 Mar 2023

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

Review on nanoparticles usage for treating thrombosis induced by SARS-CoV-2 infections

Researchers provided an overview of nanomedicine strategies to treat coronavirus disease 2019 (COVID-19)-induced thrombosis.

21 Dec 2022

Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

What is the impact of COVID-19 and organophosphates on cardiac health?

In a new study, researchers discussed the impacts of organophosphates (OP) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on cardiovascular (CVS) health.

17 Oct 2022

Amplification of venous thromboembolism risk by COVID-19 among malignancy patients

In a new study, researchers reported the mechanisms involved in COVID-19 coagulopathy and the significance of SARS-CoV-2 infections for cancer patients concerning outcomes, thromboembolic complication risks, and consequences of management strategies.

14 Oct 2022

The association of BNT16B2b2 mRNA COVID-19 vaccine with thrombocytopenia and pneumonitis: A case report

The case report of a patient who developed pneumonitis and thrombocytopenia concurrently after being administered the COVID-19 vaccine.

11 Oct 2022

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

In a new study, researchers found elevated plasma levels of myosin light chain 9 (Myl9) in COVID-19 patients with a fatal disease.

2 Aug 2022

New diagnostic procedure could help start optimal stroke treatment in a timely manner

A blood clot in the brain that blocks the supply of oxygen can cause an acute stroke. In this case, every minute counts.

8 Jun 2022

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Investigators demonstrated S100A9 as an inflammatory biomarker among hospitalized SARS-CoV-2 patients.

20 May 2022

Robotic surgery reduces readmissions, benefits patients' overall recovery

A new study, published in JAMA, has found that robotic surgery reduces the chance of readmission by half (52 per cent), and revealed a "striking" four-fold (77 per cent) reduction in prevalence of blood clots (deep vein thrombus and pulmonary emboli) - a significant cause of health decline and morbidity - when compared to patients who had open surgery.

15 May 2022

Free SARS-CoV-2 spike protein fragments may trigger platelet activation and clot formation in COVID-19

In a recent study under review in the Nature Portfolio journal and currently available on the Research Square* preprint server, researchers investigated the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (SP) in the thrombi (or blood clots).

5 May 2022

Role of complement factor H-related protein 5 in venous thromboembolism and COVID-19

A new study discussed the role of complement factor H-related protein 5 (CFHR5) in venous thromboembolism (VTE) patients and hospitalized COVID-19 patients.

25 Apr 2022

New insight about how blood clots are formed during wound healing

Research carried out by RCSI University of Medicine and Health Sciences has revealed new information about how blood clots are formed during wound healing.

11 Mar 2022

Studying coagulopathy in COVID-19

A new study published in the journal Diagnostics provided an overview of ROTEM with a particular focus on interpreting the symmetrical clot formation curve. Researchers also introduced new parameters that could aid in distinguishing between COVID-19 patients and outcomes.

28 Feb 2022

Scientists decipher molecular cause of cerebral venous thrombosis

Cerebral venous thrombosis is a rare, often severe disease that has been brought to public attention by the Covid 19 pandemic. A research group from Würzburg has now succeeded for the first time in deciphering a molecular cause of this disease.

11 Feb 2022

Clinical trial compares Amulet with Watchman FLX device for percutaneous left atrial appendage closure

SWISS-APERO is the first randomized clinical trial comparing Amulet with the new generation Watchman FLX device in terms of residual left atrial appendage (LAA) patency after percutaneous LAA closure (LAAC) as evaluated by 45-day cardiac computed tomography angiography (CCTA).

8 Nov 2021

Caspase-11 identified as regulator of inflammatory pathology in SARS-CoV-2 infections

New findings identify CASP4/11 as detrimental to inflammation and coagulopathy associated with SARS-CoV-2 infection.

28 Sep 2021