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Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study by Johns Hopkins Medicine researchers. [More]
Novel combination therapy slows cancer growth in patients with advanced solid tumors

Novel combination therapy slows cancer growth in patients with advanced solid tumors

A phase 1 clinical trial testing a novel combination therapy developed by scientists at VCU Massey Cancer Center slowed the growth of cancer in the majority of trial participants, which were patients with advanced solid tumors. [More]
Maternal hypothyroxinemia may contribute to increased risk of schizophrenia in infants

Maternal hypothyroxinemia may contribute to increased risk of schizophrenia in infants

A study published in Biological Psychiatry reveals a new link between low levels of the thyroid hormone thyroxine during pregnancy and risk of schizophrenia in the offspring. [More]
New, portable molecular imaging system combines optical imaging and scintigraphy

New, portable molecular imaging system combines optical imaging and scintigraphy

Bigger isn't always better, especially when it comes to a new and surprisingly portable molecular imaging system that combines optical imaging at the surface level and scintigraphy, which captures the physiological function of what lies beneath, announced developers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging. [More]
Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Aggressive neuroendocrine cancer is something of a dark horse--a rare, elusive and persevering force linked to discouraging long-term survival rates. [More]
Researchers find increased cancer incidence among patients with primary immunodeficiency disorders

Researchers find increased cancer incidence among patients with primary immunodeficiency disorders

Primary immunodeficiency disorders are a group of more than 300 single gene defects that affect the role of the immune system and prevent it from functioning properly. When Roswell Park Cancer Institute researchers evaluated the overall and site-specific incidence of cancer among patients registered in the United States Immune Deficiency Network, they found increased cancer incidence rates among patients with primary immunodeficiency diseases — and, in particular, a significant increase in lymphoma cases. [More]
Adolescents and young adults have lower cancer survival rates compared to children

Adolescents and young adults have lower cancer survival rates compared to children

More young people of all ages are surviving cancer than ever before, but new research published today in The Lancet Oncology journal shows that adolescents and young adults have a lower chance of surviving eight relatively common types of cancer than children, according to the latest data from a long-running study of cancer survival across Europe. [More]
SUSTAIN study to test effect of high-dose selenium on recovery of cardiac surgery patients

SUSTAIN study to test effect of high-dose selenium on recovery of cardiac surgery patients

Queen's University researcher Daren Heyland is leading a study that aims to reduce the risk of complications and improves recovery of cardiac surgery patients. [More]
New portable device with hand-held probe could help reduce unnecessary thyroid cancer surgery

New portable device with hand-held probe could help reduce unnecessary thyroid cancer surgery

A team of experts from around Europe has come together to develop a portable device with a hand-held probe that will dramatically reduce invasive diagnostic and therapeutic procedures in the treatment of thyroid nodules, saving approximately €450 million Euros every year. [More]
Bayer-new phase 3 liver cancer data

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress. [More]
Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Researchers at UT Southwestern Medical Center have identified a blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder, or ASD. [More]
New national database could help identify major influences on miscarriage

New national database could help identify major influences on miscarriage

A new national database could help relieve the misery of miscarriage for thousands of women. [More]
Nocturnal hypoxemia closely linked to diabetic microvascular complications

Nocturnal hypoxemia closely linked to diabetic microvascular complications

Examining the poorly understood link between obstructive sleep apnea (OSA) and type 2 diabetes complications, researchers identified specific measures of low blood oxygenation that are associated with impaired kidney function and diabetic nephropathy. [More]
Novel function of PLK1 gene in prostate cancer metastasis

Novel function of PLK1 gene in prostate cancer metastasis

Researchers at VCU Massey Cancer Center have uncovered a novel function of the gene PLK1 (polo-like kinase 1) that helps prostate cancer cells metastasize (spread) to other parts of the body. This mechanism highlights new potential targets for cancer therapies and challenges the previous understanding of PLK1's role in cancer growth and progression. [More]
LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

A phase I study of the drug LOXO-101 appears to significantly reduce tumors in patients with varied types of genetically defined cancer, according to a study led by The University of Texas MD Anderson Cancer Center. [More]
International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

Led by researchers at the University of Pittsburgh School of Medicine, an international panel of pathologists and clinicians has reclassified a type of thyroid cancer to reflect that it is noninvasive and has a low risk of recurrence. The name change, described today in JAMA Oncology, is expected to reduce the psychological and medical consequences of a cancer diagnosis, potentially affecting thousands of people worldwide. [More]
Coronary heart disease, cancer less likely among people with learning disabilities

Coronary heart disease, cancer less likely among people with learning disabilities

Coronary heart disease and cancer rates among people with learning disabilities are nearly a third lower than the general population, says new research. [More]
Brominated fire retardants overstimulate aldosterone in a way that may lead to cardiovascular disease

Brominated fire retardants overstimulate aldosterone in a way that may lead to cardiovascular disease

Brominated fire retardants, used in many consumer products and known to cause hormonal irregularities, overstimulates an adrenal gland hormone in a way that may lead to the development of cardiovascular disease, new research in human cells finds. Researchers will present their study results Saturday at the Endocrine Society's 98th annual meeting in Boston. [More]
Endocrine Society issues recommendations to improve care for people with diabetes

Endocrine Society issues recommendations to improve care for people with diabetes

To provide integrated care for people who have diabetes and may be at risk of developing related medical complications, the U.S. health care system needs to continue building effective multidisciplinary care team models, according to new recommendations issued by the Endocrine Society today. [More]
New ultra-sensitive technique shows promise as diagnostic tool for cancers, HIV

New ultra-sensitive technique shows promise as diagnostic tool for cancers, HIV

A common theme in medicine is that detecting a disease early on can lead to more effective treatments. This relies partly on luck that the patient gets screened at the right time, but more important is that the testing techniques are sensitive enough to register the minuscule hints that diseases leave in the blood stream. [More]
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