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CMC Biologics, River Vision sign manufacturing agreement for Teprotumumab to treat Grave's Orbitopathy

CMC Biologics, River Vision sign manufacturing agreement for Teprotumumab to treat Grave's Orbitopathy

CMC Biologics, a global leader in clinical and commercial manufacturing of therapeutic proteins, and River Vision Development Corporation (River Vision), a private company focused on ophthalmology, announced today that they have entered into an agreement for the process transfer and cGMP production of RV001 (Teprotumumab) – a recombinant monoclonal antibody targeting insulin-like growth factor 1 that is in development for treatment of Grave's Orbitopathy and other indications. [More]
Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

The Endocrine Society today announced it has chosen 18 accomplished endocrinologists as winners of the organization's prestigious 2016 Laureate Awards. [More]
Mayo Clinic researchers study HDAC inhibitors to find effective treatments for anaplastic thyroid cancer

Mayo Clinic researchers study HDAC inhibitors to find effective treatments for anaplastic thyroid cancer

In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic's Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal. [More]
Brown University explores effect of chemical exposures on the brain and thyroid during pregnancy, childhood

Brown University explores effect of chemical exposures on the brain and thyroid during pregnancy, childhood

Exposure to the endocrine disrupting chemicals bisphenol A, triclosan and phthalates is ubiquitous in the United States, raising concerns that they may affect health. With a new four-year, $1.5 million grant from the National Institutes of Health, Brown University epidemiologist Joseph Braun will try to close a gap in research: the effect of these exposures on the brain and thyroid during pregnancy and childhood. [More]
Phase 3 SUMIT study: Selumetinib fails to meet primary endpoint in patients with metastatic uveal melanoma

Phase 3 SUMIT study: Selumetinib fails to meet primary endpoint in patients with metastatic uveal melanoma

AstraZeneca today announced that the Phase 3 SUMIT study of selumetinib in combination with dacarbazine for the treatment of patients with metastatic uveal melanoma did not meet its primary endpoint of progression free survival. This combination therapy showed an adverse event profile generally consistent with current knowledge of the safety profiles of dacarbazine and selumetinib. [More]
Invuity's proprietary photonics technology recognized for improving patient safety

Invuity's proprietary photonics technology recognized for improving patient safety

Invuity, Inc., a leading surgical photonics company, today reported that The Joint Commission has recognized its proprietary photonics technology as an important innovation in the prevention of unintended retained foreign objects (URFOs) that are left inside patients during surgery. [More]
Study shows that moderate suppression of TSH may be enough even in high-risk thyroid cancer

Study shows that moderate suppression of TSH may be enough even in high-risk thyroid cancer

A study of long-term thyroid cancer outcomes shows, among other findings, that moderate suppression of thyroid-stimulating hormone (TSH), which drives the disease, may be as beneficial as more extreme hormone suppression. [More]
UT Southwestern dermatologist improves technique to treat skin discoloration from vitiligo

UT Southwestern dermatologist improves technique to treat skin discoloration from vitiligo

A UT Southwestern Medical Center dermatologist has improved a technique to transplant pigment cells that can repair the affected area of skin discoloration from vitiligo. [More]
Risk of hepatobiliary cancer, cardiovascular diseases later in life is higher in women with ICP

Risk of hepatobiliary cancer, cardiovascular diseases later in life is higher in women with ICP

In a new study of more than 125,000 pregnant women in Sweden, researchers found that the risk of hepatobiliary cancer and immune-mediated and cardiovascular diseases later in life is higher in women with intrahepatic cholestasis of pregnancy (ICP) than in women without this condition. [More]
Botanic Choice releases list of top 10 supplements for 2015

Botanic Choice releases list of top 10 supplements for 2015

Botanic Choice has just released its list of the top 10 most popular supplements for the first half of 2015. [More]
UPCI scientists lead a panel of experts in revising guidelines for thyroid cancer tests

UPCI scientists lead a panel of experts in revising guidelines for thyroid cancer tests

University of Pittsburgh Cancer Institute scientists recently led a panel of experts in revising national guidelines for thyroid cancer testing to reflect newly available tests that better incorporate personalized medicine into diagnosing the condition. [More]
Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. Mitchell Lazar, MD, PhD, Raymond Soccio, MD, PhD, and colleagues at the Perelman School of Medicine at the University of Pennsylvania, aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders. [More]
ALPINION launches new E-CUBE Series ultrasound system

ALPINION launches new E-CUBE Series ultrasound system

ALPINION MEDICAL SYSTEMS Co., Ltd., announced today the launch of a new E-CUBE Series ultrasound system. Developed to enhance user experience and patient care in a range of clinical areas, the E-CUBE 15 EX produces superb image quality. With advanced imaging technologies, this system delivers outstanding clinical performance in women's health, general imaging, and shared service applications. [More]
Two-thirds of patients with T4a larynx cancer not receiving total laryngectomy

Two-thirds of patients with T4a larynx cancer not receiving total laryngectomy

Despite findings of previous studies and published guidelines, nearly two-thirds of patients with T4a larynx ("voice box") cancer are not receiving a total laryngectomy (surgical removal of the larynx), the recommended form of treatment, and as a result, have significantly worse survival rates versus those treated with a total laryngectomy, a new study published in the International Journal of Radiation Oncology, Biology and Physics by experts at Penn Medicine found. [More]
STIOLTO RESPIMAT Inhalation Spray now available for treatment of COPD across the U.S.

STIOLTO RESPIMAT Inhalation Spray now available for treatment of COPD across the U.S.

Boehringer Ingelheim Pharmaceuticals, Inc. announced today that STIOLTO RESPIMAT (tiotropium bromide and olodaterol) Inhalation Spray is now available by prescription at pharmacies across the United States. [More]
Veracyte named to Bay Area News Group's Top Workplaces list for second consecutive year

Veracyte named to Bay Area News Group's Top Workplaces list for second consecutive year

Veracyte, Inc., a molecular diagnostics company pioneering the field of molecular cytology, today announced that it has been named to the Bay Area News Group's prestigious Top Workplaces list for the second year in a row. The news group selects Top Workplace winners based solely on an annual survey of Bay Area-company employees. [More]
Research: Fetuses more vulnerable to some pollutants that penetrate into feto-maternal system

Research: Fetuses more vulnerable to some pollutants that penetrate into feto-maternal system

Toxic environmental contaminants are increasingly known to cause a number of severe health problems, in particular on fetuses, including heart failure, low cognitive ability, delayed development, and neurobehavioral disorders. [More]
PD linked to increased cancer risk in Asian population

PD linked to increased cancer risk in Asian population

A Taiwanese population-based cohort study reports an increased risk of most cancers in patients with Parkinson’s disease, contrasting with findings in Western populations. [More]
The Lancet Oncology publishes results of CYRAMZA (ramucirumab) Phase III trial for HCC treatment

The Lancet Oncology publishes results of CYRAMZA (ramucirumab) Phase III trial for HCC treatment

Eli Lilly and Company announced that The Lancet Oncology has published results of the Phase III REACH trial that evaluated CYRAMZA (ramucirumab) as a second-line treatment for people with hepatocellular carcinoma (HCC), also known as liver cancer. While the REACH trial's primary endpoint of overall survival favored the CYRAMZA arm, it was not statistically significant. [More]
Young thyroid cancer patients with lymph node involvement at increased risk of dying

Young thyroid cancer patients with lymph node involvement at increased risk of dying

Patients older than age 45 with thyroid cancer that has spread to neck lymph nodes have long been considered at higher risk of dying, but the same has not been true for younger patients. [More]
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