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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.
Researchers develop new method that can target drug delivery to the lung

Researchers develop new method that can target drug delivery to the lung

Researchers from Columbia Engineering and Columbia University Medical Center have developed a new method that can target delivery of very small volumes of drugs into the lung. [More]
Gene therapy restores visual function in mouse model of LCA1

Gene therapy restores visual function in mouse model of LCA1

Mice lacking the protein retGC1, which is deficient in humans suffering Leber congenital amaurosis-1 (LCA1), a disorder that causes severe visual impairment beginning in infancy, received gene therapy to replace retGC1 and showed fully restored visual function that persisted for at least 6 months. [More]
Powerful explosive devices of 21st century warfare prompt urgent calls to re-engineer protective gear

Powerful explosive devices of 21st century warfare prompt urgent calls to re-engineer protective gear

Battle-inflicted head injuries are as old as war itself, evidenced by the copper helmets worn by Bronze Age soldiers to deflect blows from spears and axes. Over the ensuing millennia, as weapons evolved, so did armor. Today, the powerful explosive devices of 21st century warfare have once again raised the stakes, prompting urgent calls to re-engineer protective gear. [More]
University of Nottingham to lead £6.5m research project that aims to develop next generation biomaterials

University of Nottingham to lead £6.5m research project that aims to develop next generation biomaterials

The University of Nottingham is to lead a £6.5m research project which aims to make the leap from 2D to 3D in the development of advanced materials and realise the true potential of regenerative medicine and medical devices for the future. [More]
Transplanting multi-layered sheet of liver cells into damaged liver improves function in test animals

Transplanting multi-layered sheet of liver cells into damaged liver improves function in test animals

Liver transplantation is currently the only established treatment for patients with end stage liver failure. However, this treatment is limited by the shortage of donors and the conditional integrity and suitability of the available organs. Transplanting donor hepatocytes (liver cells) into the liver as an alternative to liver transplantation also has drawbacks as the rate of survival of primary hepatocytes is limited and often severe complications can result from the transplantation procedure. [More]
Scientists bridge gap between two separate pieces of embryonic mouse intestine

Scientists bridge gap between two separate pieces of embryonic mouse intestine

University of Manchester scientists have bridged a gap between two separate pieces of small intestine kept alive outside the body, in an advance which could have implications for surgery in human adults and babies. [More]
Scientists develop technique to rejuvenate cells from older osteoarthritis patients

Scientists develop technique to rejuvenate cells from older osteoarthritis patients

A research team at York has adapted the astonishing capacity of animals such as newts to regenerate lost tissues and organs caused when they have a limb severed. [More]
SAGE partners with The Katie Piper Foundation to launch journal Scars, Burns & Healing

SAGE partners with The Katie Piper Foundation to launch journal Scars, Burns & Healing

SAGE is delighted to announce a new partnership with The Katie Piper Foundation to launch the unique journal Scars, Burns & Healing. The journal brings together the specialist focus of scar and burns research with the breadth of the science and medicine related to wound healing, and will be accepting its first submissions from summer 2015. [More]
NFIX protein drives NSC differentiation toward oligodendrocytes

NFIX protein drives NSC differentiation toward oligodendrocytes

An international team of researchers has shown that NFIX, a protein that regulates neuronal stem cell activity (NSC), also has a role in driving NSC differentiation toward oligodendrocytes, a type of glial cell. These cells produce the myelin that surrounds and protects neurons. [More]
Penn researchers identify major genetic factor that keeps moles in non-cancerous, no-growth state

Penn researchers identify major genetic factor that keeps moles in non-cancerous, no-growth state

Moles are benign tumors found on the skin of almost every adult. Scientists have known for years that a mutation in the BRAF gene makes them start growing, but until now haven't understood why they stop. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania have identified a major genetic factor that keeps moles in their usual non-cancerous, no-growth state. [More]
Researchers show how realistic environments affect growth of cancer tumors in bones

Researchers show how realistic environments affect growth of cancer tumors in bones

Researchers at Rice University and University of Texas MD Anderson Cancer Center have developed a way to mimic the conditions under which cancer tumors grow in bones. [More]
Researchers use silk fibers to grow stem cells into salivary gland cells

Researchers use silk fibers to grow stem cells into salivary gland cells

The silkworm, which produces the essential ingredient for fine silk fabric, also plays a critical role in a new process designed to provide relief for millions of individuals with dry mouth, a devastating oral and systemic health issue. [More]
Leading scientists to meet in Southampton to discuss new technologies to create living tissues

Leading scientists to meet in Southampton to discuss new technologies to create living tissues

Leading scientists from the UK and around the world will meet at the University of Southampton next week (20 and 21 July) to discuss new technologies to create new, living tissues in the lab and to help our bodies regenerate themselves. [More]
New study reveals highly promising approach to coating tissue engineered constructs

New study reveals highly promising approach to coating tissue engineered constructs

A new study showing the ability to apply a thin coating of viable respiratory epithelial cells to tissue engineered constructs using a commercially available spray device is especially promising for therapeutic approaches in development to repair or replace challenging structures such as trachea or bronchi. [More]
Ultrasound treatment speeds up skin healing among diabetics and the elderly

Ultrasound treatment speeds up skin healing among diabetics and the elderly

Healing times for skin ulcers and bedsores can be reduced by a third with the use of low-intensity ultrasound, scientists from the University of Sheffield and University of Bristol have found. [More]
R-Japan receives license for cell processing facility

R-Japan receives license for cell processing facility

R-Japan Co.,Ltd. obtained the license of cell processing facility under the Act on the Safety of Regenerative Medicine from the Ministry of Health, Labour and Welfare Kinki Bureau of Health and Welfare on June 29, 2015. [More]

Case report published on first use of 3D printed scaffold for periodontal tissue engineering

Today, the International and American Associations for Dental Research published a case report on the first application of a 3D printed scaffold for periodontal tissue engineering in a human patient, along with a review of 3D printing for oral and craniofacial tissue engineering. [More]
Ontario announces $25 million investment to support new treatments for people with chronic diseases

Ontario announces $25 million investment to support new treatments for people with chronic diseases

Ontario is investing $25 million over five years to support new treatments and therapies for people living with chronic diseases, such as cancer, multiple sclerosis and diabetes. [More]

New tissue 'scaffold' technology could one day help produce large organs

Scientists have developed a new tissue 'scaffold' technology that could one day enable the engineering of large organs. Research led by the Universities of Bristol and Liverpool has shown that it is possible to combine cells with a special scaffold to produce living tissue in the laboratory. It is hoped this can then be implanted into patients as a way of replacing diseased parts of the body. [More]
‘VascuBone Toolbox’ provides components required for customised vascularised bone implant

‘VascuBone Toolbox’ provides components required for customised vascularised bone implant

The EU project VascuBone was coordinated by the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB and has reached the end of a 5-year funding period. [More]
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