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Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models. [More]

MIT researchers test tiny origami robot that unfolds from swallowed capsule in simulated stomach

In experiments involving a simulation of the human esophagus and stomach, researchers at MIT, the University of Sheffield, and the Tokyo Institute of Technology have demonstrated a tiny origami robot that can unfold itself from a swallowed capsule and, steered by external magnetic fields, crawl across the stomach wall to remove a swallowed button battery or patch a wound. [More]
NHS: a health service or an illness service? An interview with Dr Paula Crick

NHS: a health service or an illness service? An interview with Dr Paula Crick

I've been a nurse for almost 32 years and one of the things that has always been difficult for me to comprehend is that all too often we treat people who are sick, having missed opportunities to prevent, screen or intervene. [More]
PAH role proposed for left heart failure biomarker

PAH role proposed for left heart failure biomarker

Levels of galectin-3 are elevated in patients with pulmonary arterial hypertension and correlate with disease severity, research shows. [More]
New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

With every heart attack, billions of cardiomyocytes, the contracting heart muscle cells that make the heart pump time after time over a lifetime, are lost which can lead to heart failure or injury. Stem cell-based replacement strategies could open new and much needed therapeutic avenues. [More]
Framework for improving chemical hazard assessment without animals

Framework for improving chemical hazard assessment without animals

A new paper published in Regulatory Toxicology and Pharmacology, co-authored by the Physicians Committee for Responsible Medicine, calls for ongoing development and regulatory acceptance of adverse outcome pathways (AOPs), a framework for improving chemical hazard assessment by prioritizing modern test methods that reduce animal use. [More]
Shire announces resubmission of lifitegrast NDA to FDA for treatment of dry eye disease in adults

Shire announces resubmission of lifitegrast NDA to FDA for treatment of dry eye disease in adults

Shire plc today announced it has resubmitted the New Drug Application (NDA) to the U.S. Food and Drug Administration for its investigational candidate, lifitegrast, for the treatment of signs and symptoms of dry eye disease in adults. Shire resubmitted the NDA in response to the complete response letter (CRL) the company received from the FDA on October 16, 2015. [More]
First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

First patient enrolled in ThromboGenics' Phase II CIRCLE study of ocriplasmin in NPDR patients

ThromboGenics NV, an integrated biopharmaceutical company focused on developing and commercializing innovative treatments for diabetic eye disease, today announces that the first patient has been enrolled in its Phase II CIRCLE study evaluating the efficacy and safety of multiple doses of ocriplasmin in inducing total posterior vitreous detachment (PVD) in patients with non-proliferative diabetic retinopathy (NPDR). [More]
AiCure closes $12.25 million in Series A fundraising round

AiCure closes $12.25 million in Series A fundraising round

AiCure, an artificial intelligence company connecting the world's patients to better treatments and improved health, has closed a Series A fundraising round with $12.25 million. The consortium is led by New Leaf Venture Partners, with additional participation from Pritzker Group Venture Capital, Tribeca Venture Partners, and Biomatics Capital, established by Boris Nikolic, former Chief Advisor for Science and Technology to Bill Gates. [More]
Several therapies for hemophilia A, hemophilia B and hemophilia with inhibitors to be launched between 2015-2025

Several therapies for hemophilia A, hemophilia B and hemophilia with inhibitors to be launched between 2015-2025

Decision Resources Group forecasts that several therapies will launch for hemophilia A, hemophilia B and hemophilia with inhibitors in the United States and Europe during our 2015-2025 study period. [More]

Minority groups in the U.S. less likely than white people to trust doctors

When it comes to trust in their physicians, minority groups in the United States are less likely than white people to believe their doctors care about them, according to research by University of Pennsylvania's Abigail Sewell. [More]
TCS, VUMC partner to drive innovation in healthcare and life sciences fields

TCS, VUMC partner to drive innovation in healthcare and life sciences fields

Tata Consultancy Services, a leading global IT services, consulting and business solutions organization, today announced a new partnership with Vanderbilt University Medical Center to drive innovation in the healthcare and life sciences fields. [More]

Merus reports revenues of $49.0 million for fiscal 2015

Merus Labs International Inc. is pleased to report its financial results for fiscal year ending September 30, 2015. [More]
Expert proposes new solution to current gridlock over regulation of dietary supplements

Expert proposes new solution to current gridlock over regulation of dietary supplements

A former principal deputy commissioner of the U.S. Food and Drug Administration is proposing a solution to the current gridlock over the regulation of dietary supplements: Focus less on whether these vitamins, minerals and herbal extracts actually do what they claim and instead take important steps to improve their safety. [More]
International consortium provides standard protocol for using Oxford Nanopore's DNA-sequencing device

International consortium provides standard protocol for using Oxford Nanopore's DNA-sequencing device

The MinION, a handheld DNA-sequencing device developed by Oxford Nanopore, has been tested and evaluated by an independent, international consortium coordinated by EMBL's European Bioinformatics Institute (EMBL-EBI). [More]
LabStyle Innovations closes $2.5 million funding round

LabStyle Innovations closes $2.5 million funding round

LabStyle Innovations Corp., developer of the Dario™ Diabetes Management Solution, today announced it recently closed a round of funding totaling approximately $2.5 million. [More]

Syneron Medical's second quarter 2015 revenue up 14% to $73.5 million

Syneron Medical Ltd., a leading global aesthetic device company, today announced financial results for the three month period ended June 30, 2015. [More]
MiMedx Group reports record revenues and earnings for Q2 2015

MiMedx Group reports record revenues and earnings for Q2 2015

MiMedx Group, Inc., the leading regenerative medicine company utilizing human amniotic tissue and patent-protected processes to develop and market advanced products and therapies for the Wound Care, Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic and Dental sectors of healthcare, announced today its record results for the second quarter of 2015. [More]

Limelight Health secures $3 million in Series A funding from MassMutual Ventures

Limelight Health, provider of mobile enterprise technology for the health insurance industry, announced today it has received $3 million in Series A funding from MassMutual Ventures, the corporate venture capital arm of Massachusetts Mutual Life Insurance Company, and AXA Strategic Ventures. [More]
IU psychologist receives two NIH grants to bring evidence-based treatment into community mental health centers

IU psychologist receives two NIH grants to bring evidence-based treatment into community mental health centers

With a pair of new National Institutes of Health grants totaling nearly $3 million, Indiana University clinical psychologist Cara Lewis will tackle two major issues in the effort to bring evidence-based mental health treatment into community mental health centers. [More]
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