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LMU researchers shed light on DNA repair mechanisms in Cockayne syndrome

Cockayne syndrome is a severe autosomal recessive disorder caused by defective DNA repair mechanisms.

10 Apr 2024

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

10 Apr 2024

CMS121 holds promise for treating metabolic diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction."

9 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Researchers elucidate how gene mutation mechanism causes autism

Researchers show how mutations of gene transcription and chromatin regulation-related genes cause autism.

9 Apr 2024

New ovarian atlas paves the way for extended fertility and hormone restoration

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

5 Apr 2024

Modeled human embryo produces a membrane that surrounds the developing embryo

A MedUni Vienna study team led by geneticist Markus Hengstschläger has used a stem cell model to model the earliest stages of embryonic development and to characterize the membrane that surrounds the embryo, conferring shape and stability.

5 Apr 2024

Computational tools predict protein-RNA interactions

Researchers from Aarhus University and the Italian Institute of Technology have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes.

3 Apr 2024

Study explores how cannabis use affects breast milk and lactation

Study reviews the impact of cannabis use during pregnancy and lactation, highlighting potential changes in breast milk composition and lactation due to cannabinoid effects.

3 Apr 2024

Space travel alters human vascular cell function, study finds

Study investigates the transcriptomic changes in human vascular smooth muscle cells exposed to spaceflight, revealing significant alterations in gene expression affecting cellular function and phenotype.

31 Mar 2024

Uncovering gender-specific genetic alterations in cancer

Recent research spearheaded by Chunmei Cui at the State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, China, casts a new light on the nuanced interplay between gender and cancer, uncovering significant sex-specific disparities in copy number alterations (CNA) across various cancer types.

29 Mar 2024

Genetic and lifestyle factors linked to brain network aging, study reveals

Research highlights the impact of genetic and lifestyle factors on a brain network particularly sensitive to aging, schizophrenia, and Alzheimer's disease, using data from nearly 40,000 UK Biobank participants to investigate modifiable risk factors and genetic associations.

28 Mar 2024

Exploring the link between prenatal nutrition and congenital craniofacial malformations

The complex development of craniofacial skeletal structures and improve treatments for congenital craniofacial malformations.

27 Mar 2024

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields.

26 Mar 2024

Key Charpentier/Doudna CRISPR patent upheld by China National Intellectual Property Administration

RS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, today announced its patent CN201380038920.6 was upheld by the CNIPA in response to an invalidation challenge.

From ERS Genomics 26 Mar 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form of cancer.

22 Mar 2024

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's and other diseases.

21 Mar 2024

Bioengineering edible mycelium to enhance nutritional value, color, and flavor

A modular synthetic biology toolkit for Aspergillus oryzae, an edible fungus used in fermented foods.

21 Mar 2024

Enhancing the safety and efficacy of breast and ovarian cancer treatment

Some anti-cancer treatments not only target tumour cells but also healthy cells. If their effects on the latter are too strong, their use can become limiting.

20 Mar 2024