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Could cinnamon modulate the immune response in severe COVID-19?

A new study describes the potential for two common plant products to make a difference in the management of severe COVID-19.

18 Mar 2021

ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology

Alex's Lemonade Stand Foundation, a nonprofit foundation devoted to finding cures for all children with cancer, announces grant award recipients of their Crazy 8 Initiative.

16 Mar 2021

Backtracking occurs within SARS-CoV-2 replication-transcription complex

Researchers continue to achieve a better understanding of SARS-CoV-2, the virus behind the ongoing COVID-19 pandemic. One such effort has been reported in a new preprint on the bioRxiv server, dealing with the phenomenon of backtracking.

16 Mar 2021

Study unveils SARS-CoV-2 persistence and contamination concentration on common surfaces

A recent environmental study from the United Kingdom, currently available on the bioRxiv preprint server, shows that certain common surfaces could represent an infectious risk if contaminated with high concentrations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – albeit the level of viable viral particles is likely to be low.

15 Mar 2021

Study targets main protease of SARS-CoV-2 involved in viral replication

The main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enzyme implicated in the transcription and replication of the coronavirus. New research led by S. Samar Hasnain from the University of Liverpool in the United Kingdom used the selenium-containing drug Ebselen to analyze the SARS-CoV-2 main protease (Mpro).

14 Mar 2021

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells.

14 Mar 2021

Novel computer-guided design tool helps increase the efficiency of cell conversions

There is a great need to generate various types of cells for use in new therapies to replace tissues that are lost due to disease or injuries, or for studies outside the human body to improve our understanding of how organs and tissues function in health and disease.

13 Mar 2021

Random cellular changes play vital role in longevity beyond genetics and environment

A new model of aging takes into account not only genetics and environmental exposures but also the tiny changes that randomly arise at the cellular level.

13 Mar 2021

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Researchers have found that SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment. Therefore, strategies such as focusing on limiting the production of IFN, rather than its function, could restrict the mechanism of SARS-CoV-2 that increases its viral load with delayed or absent symptoms.

12 Mar 2021

Novel tool can add or remove sugar from proteins

Sugar has been called "evil," "toxic," and "poison." But the body needs sugars, too. Sugar molecules help cells recognize and fight viruses and bacteria, shuttle proteins from cell to cell, and make sure those proteins function.

12 Mar 2021

Researchers discover new molecular target that could treat idiopathic pulmonary fibrosis

Researchers at the University of Alabama at Birmingham have identified a new molecular target that could potentially treat the deadly, aging-related lung disease idiopathic pulmonary fibrosis (IPF).

10 Mar 2021

Vaccine mRNA not found in breast milk after COVID mRNA vaccination

A study conducted by researchers in the United States has found no evidence to suggest that the messenger RNA (mRNA) present in the Pfizer-BioNTech and Moderna vaccines that protect against coronavirus disease 2019 (COVID-19) can be transferred to human breast milk.

9 Mar 2021

Study describes the infection of human cells by intestinal pathogen during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

9 Mar 2021

Researchers report zoonotic spillover of adapted SARS-CoV-2 from minks to humans

In a recent report made available on bioRxiv* preprint server, researchers from Poland and Finland reveal a spillover event of mink-adapted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from farmed mink to humans after an extensive adaptation process.

9 Mar 2021

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands.

9 Mar 2021

Proteomics shows SARS-CoV-2 NSP7 and NSP8 forms stable dimeric unit

A new preprint, released on the bioRxiv* preprint server, describes the structure of part of the dynamic protein-RNA complex known as the replication-transcription complex (RTC), which is crucial in the replication of the large ribonucleic acid (RNA) genome of this virus.

9 Mar 2021

Sniffer dogs could be used to detect SARS-CoV-2 infections, say researchers

Researchers in Germany suggest that sniffer dogs should be considered as an additional screening tool for detecting infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

8 Mar 2021

Impairments in immune response contribute to severe COVID-19

New research by a team of scientists at University Hospital RWTH Aachen in Germany and Erasmus Medical Centre in The Netherlands characterized changes in CD8+ T cells in response to SARS-CoV-2.

8 Mar 2021

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

A new paper in the journal Life presents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells.

8 Mar 2021

Novel bioinformatics tool could help improve COVID-19 diagnosis

An interesting new study by researchers at the University of Liverpool, University of Bristol and Public Health England in the UK describes a novel bioinformatics tool used to detect subgenomic messenger ribonucleic acid (mRNA) sequences from the virus. This may help develop new diagnostic tools and model the transmission of the virus.

8 Mar 2021

Transcription News and Research

Could cinnamon modulate the immune response in severe COVID-19?

ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology

Backtracking occurs within SARS-CoV-2 replication-transcription complex

Study unveils SARS-CoV-2 persistence and contamination concentration on common surfaces

Study targets main protease of SARS-CoV-2 involved in viral replication

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Novel computer-guided design tool helps increase the efficiency of cell conversions

Random cellular changes play vital role in longevity beyond genetics and environment

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Novel tool can add or remove sugar from proteins

Researchers discover new molecular target that could treat idiopathic pulmonary fibrosis

Vaccine mRNA not found in breast milk after COVID mRNA vaccination

Study describes the infection of human cells by intestinal pathogen during spaceflight

Researchers report zoonotic spillover of adapted SARS-CoV-2 from minks to humans

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Proteomics shows SARS-CoV-2 NSP7 and NSP8 forms stable dimeric unit

Sniffer dogs could be used to detect SARS-CoV-2 infections, say researchers

Impairments in immune response contribute to severe COVID-19

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

Novel bioinformatics tool could help improve COVID-19 diagnosis

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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