Transcription News and Research

RSS

Researchers reprogram glial cells into new neurons to heal spinal cord injury

Researchers at Indiana University School of Medicine have successfully reprogrammed a glial cell type in the central nervous system into new neurons to promote recovery after spinal cord injury--revealing an untapped potential to leverage the cell for regenerative medicine.

8 Mar 2021

SARS-CoV-2 proteins are potent suppressors of innate immunity

A new study describes the strong immune-suppressing activity of SARS-CoV-2 genes, among other coronavirus genes.

5 Mar 2021

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Scientists have recently developed a novel alternative molecular display technology called Molecular Indexing of Proteins by Self Assembly (MIPSA). Their research explains how this technology overcomes the critical disadvantages of PLATO and other full-length protein array technologies.

5 Mar 2021

Delayed detection of oral fluid anti-SARS-CoV-2 antibodies increases the time to viral clearance

A prospective observational study has revealed that the late appearance of anti-SARS-CoV-2 antibodies in oral fluid, absence of fever as an early symptom, and elevated BMI are associated with delayed clearance of viral RNA in mild to moderate COVID-19 patients.

4 Mar 2021

Is transposable element expression affected by SARS-CoV-2 infection?

A study by researchers in Israel aims to establish whether TE expression is altered in SARS-CoV-2 infected cells, and explores the implications for host immune response.

1 Mar 2021

Free-ranging minks exhibit high titers of SARS-CoV-2 antibodies in Utah

Researchers at the U.S. Centers for Disease Control and Prevention (CDC) report outbreaks of coronavirus disease (COVID-19) on mink farms in Utah, United States. They surveyed around farms for evidence of exposure and found high SARS-CoV-2 titers, suggesting a possible viral transmission pathway to native wildlife.

28 Feb 2021

Efficacy of polymeric nano-micelles depends on expression level of c-Myc

The Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki in Japan, Abbreviation: iCONM) reported in ACS Nano (Impact Factor: 14.588 in 2019) together with the group of Prof. Yu Matsumoto of Otorhinolaryngology and Head and Neck Surgery (Prof. Tatsuya Yamasoba) and the group of Prof. Horacio Cabral of the Department of Bioengineering (Prof. Ryo Miyake) in the University of Tokyo that the efficacy of polymeric nano-micelles with different drug activation profile depends on the expression level of c-Myc, one of the major proto-oncogene, has been developed.

27 Feb 2021

Study demonstrates the novel agonistic effect of curcumin on lipid transcription

Curcumin is a polyphenol compound produced by plants of the Curcuma longa species and has been reported to have many physiological activities, which include anti-oxidation, anti-inflammatory, anti-cancer, and anti-amyloid properties.

27 Feb 2021

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

A new study by researchers at Brookhaven National Laboratory and Stony Brook University in the U.S. describes the key interaction between the viral envelope (E) protein and the human cell junction protein, PALS1. The latter is necessary to establish and maintain cell polarity and tight junctions between cells.

26 Feb 2021

KAUST researchers develop a safe, fast and cheap testing method to detect viruses

A safe, fast and cheap testing method that uses magnetic nanoparticles to detect viruses in both clinical and wastewater samples has been developed by KAUST researchers.

25 Feb 2021

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Researchers in Switzerland and Germany have identified host cell factors required for coronavirus replication that could serve as targets for treatment with clinically-approved drugs.

25 Feb 2021

Tumors use unique mechanism to switch on regulatory T cells for protection

Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system.

24 Feb 2021

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited.

24 Feb 2021

COVID-19 hospitalizations still high in England despite recent decline in cases, says study

Results from the latest round of the real-time assessment of community transmission study (REACT-1) study in England indicate that although coronavirus disease 2019 (COVID-19) cases have decreased, the number of hospitalizations remains high.

24 Feb 2021

GSK-3 inhibitors show promise in treating coronavirus infections

Researchers in the United States have suggested a new approach to treating infection with coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

23 Feb 2021

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?

The study began with the generation of recombinant (r)SA11 rotaviruses, into which segment 7 modified RNAs were introduced. These encoded sequences for the non-structural protein NSP3 and some parts of the viral spike.

23 Feb 2021

Influenza A virus defective interfering particles against SARS-CoV-2

In the search for a broadly acting pan-specific antiviral, an interdisciplinary team from Germany tested the previously proposed (for antiviral treatment against Influenza A infections) - Influenza A virus (IAV) defective interfering particles (DIPs). The research is published online on the bioRxiv preprint server.

23 Feb 2021

No evidence of SARS-CoV-2 fusing into the human genome

New data from researchers led by Majid Kazemian from Purdue University refutes claims from recent studies suggesting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could create a host-virus chimeric RNA. Their team found SARS-CoV-2 does not combine with the human genome.

22 Feb 2021

Applications of Artificial Intelligence in COVID-19 ICU and ER situations

The overwhelming increase in critically ill COVID-19 patients, who urgently require intensive care units (ICU) and emergency departments (ED), has challenged healthcare systems worldwide.

22 Feb 2021

Scientists find new therapeutic approach to effectively treat age-related macular degeneration

Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy.

22 Feb 2021

Transcription News and Research

Researchers reprogram glial cells into new neurons to heal spinal cord injury

SARS-CoV-2 proteins are potent suppressors of innate immunity

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Delayed detection of oral fluid anti-SARS-CoV-2 antibodies increases the time to viral clearance

Is transposable element expression affected by SARS-CoV-2 infection?

Free-ranging minks exhibit high titers of SARS-CoV-2 antibodies in Utah

Efficacy of polymeric nano-micelles depends on expression level of c-Myc

Study demonstrates the novel agonistic effect of curcumin on lipid transcription

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

KAUST researchers develop a safe, fast and cheap testing method to detect viruses

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Tumors use unique mechanism to switch on regulatory T cells for protection

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

COVID-19 hospitalizations still high in England despite recent decline in cases, says study

GSK-3 inhibitors show promise in treating coronavirus infections

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?

Influenza A virus defective interfering particles against SARS-CoV-2

No evidence of SARS-CoV-2 fusing into the human genome

Applications of Artificial Intelligence in COVID-19 ICU and ER situations

Scientists find new therapeutic approach to effectively treat age-related macular degeneration

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News