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Study identifies molecular pathway in liver cancer development

As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths.

23 Apr 2024

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting.

18 Apr 2024

CMS121 holds promise for treating metabolic diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction."

9 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form of cancer.

22 Mar 2024

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's and other diseases.

21 Mar 2024

New compounds show potential to mimic benefits of exercise

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise.

18 Mar 2024

New method simplifies production of limb progenitor cells from fibroblasts

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

4 Mar 2024

Advancing gene regulatory network inference with causal discovery and graph neural networks

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes.

23 Feb 2024

IκBζ protein holds potential for treating autoimmune conditions

Our immune system is remarkably powerful. It quickly assembles teams of cells to eliminate threats inside our bodies.

21 Feb 2024

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

16 Feb 2024

New breakthrough in pancreatic cancer research could help slow the disease's deadly spread

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of California, Davis have reached a new breakthrough in pancreatic cancer research-;eight years in the making. It could help slow the disease's deadly spread.

14 Feb 2024

Study reveals a crucial survival tactic employed by cancer cells

A study led by the group of Didier Trono at EPFL has revealed a crucial survival tactic employed by cancer cells.

12 Feb 2024

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."

8 Feb 2024

Study pinpoints a protein linked to metastatic pancreatic cancer

Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.

7 Feb 2024

Extra fingers and double hearts: Scientists decode how tiny mutations can derail development

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

6 Feb 2024

Transcription Factors News and Research

Study identifies molecular pathway in liver cancer development

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

CMS121 holds promise for treating metabolic diseases

Research identifies how leukemia develops resistance to first line treatments

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

New compounds show potential to mimic benefits of exercise

New method simplifies production of limb progenitor cells from fibroblasts

Advancing gene regulatory network inference with causal discovery and graph neural networks

IκBζ protein holds potential for treating autoimmune conditions

Researchers introduce a pioneering approach to combat neurodegenerative diseases

New breakthrough in pancreatic cancer research could help slow the disease's deadly spread

Study reveals a crucial survival tactic employed by cancer cells

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

Study pinpoints a protein linked to metastatic pancreatic cancer

Extra fingers and double hearts: Scientists decode how tiny mutations can derail development

Study shines light on the role of transcription factors during early embryonic development

Study links specific inflammatory markers to increased cancer risk

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

New insights on how diet regulates allergic responses

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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