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NIH is solicits suggestions for new initiatives under the aegis of the NIH Roadmap

The NIH is actively soliciting suggestions for new initiatives to be implemented under the aegis of the NIH Roadmap. The NIH intends to spend $30-50 million/year from within the currently projected Roadmap budget for approximately 5-8 new initiatives, beginning in FY2008.

6 Nov 2006

Study extends the number of antigenic peptides that can be produced from a single protein

Understanding medical research problems often relies on the direct, linear relationship between the sequence of a protein and the DNA encoding that protein. In fact, colinearity of DNA and protein sequences is thought to be a fundamental feature of the universal genetic code.

13 Sep 2006

Deadly duo of crime and drug abuse can be cut by effective treatments

According to a landmark scientific report released by the National Institute on Drug Abuse (NIDA), money would be saved and crime would be reduced if communities put into place effective treatments for drug abuse and addiction.

26 Jul 2006

Belfer Foundation funds new translational cancer institute

The Arthur and Rochelle Belfer Foundation has pledged $8 million to create the Arthur and Rochelle Belfer Institute of Hematology and Medical Oncology at Weill Medical College of Cornell University.

25 Jul 2006

Protein called Elk-1appears to play role in neurodegeneration and schizophrenia

Pprotein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein - typically active in the nucleus - could play a role in cell death and mitochondria-related diseases such as neurodegeneration and schizophrenia.

9 Jun 2006

Researchers discover the presence of the genetic material RNA in the centrosome

Researchers have discovered the presence of the genetic material RNA in the centrosome, the organizing structure inside each cell that assures proper cell division.

6 Jun 2006

Scientists use "small interfering RNAs" to block the spread of human colorectal cancer cells

Using one of the newest and most powerful tools of biomedical science, University of Texas Medical Branch at Galveston (UTMB) researchers have scored a dramatic success in the battle against colorectal cancer.

1 Jun 2006

Study sheds light on cancer susceptibility and disease involving bone-marrow failure

Defective protein production can occur in cells even when the genes controlling those proteins are normal, according to a new study to be published May 12 in Science.

12 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

Scientists unlock more secrets of HIV and SARS

UK scientists have cracked one of the key biological processes used by viruses such as HIV and SARS when they replicate according to a paper published in the journal Nature tomorrow (11 May). Viruses are able to interfere with the host cell processes that our bodies use to replicate cells, and protein synthesis is often one of their targets.

10 May 2006

DNA taxi

Despite few successes to date, gene therapy is a highly promising approach for medical therapy in the future.

1 May 2006

Microarray analysis could lead to better understanding of mechanisms underlying the genetic propensity toward excessive drinking

The meta analysis, which examined more than 4.5 million data points on more than 100 microarrays from mouse models, also identified more than 1,300 functional groups, including signaling and transcription pathways, which may also play an important role in establishing a capacity for a "high level of alcohol consumption."

18 Apr 2006

Epstein-Barr virus infection linked to multiple sclerosis

Young adults with high levels of antibodies against the Epstein-Barr virus, the virus that most often causes mononucleosis, may be more likely to develop multiple sclerosis 15 to 20 years later, according to a study in the Archives of Neurology.

11 Apr 2006

Wobble pairs make RNA more reactive

The wealth of information contained in a strand of genetic material boils down to sequences of matched pairs of nucleotides that cellular machinery decodes to construct proteins.

13 Mar 2006

MIT researchers capture virus in extraordinary detail

Fifty years after MIT researchers pioneered the use of electron microscopy to study viruses, MIT scientists have helped produce the most detailed images yet of the tiny infectious agents.

21 Feb 2006

New understanding of the molecular genetics of successful fertilization

A new paper in the February 15th issue of Genes & Development lends novel insight into the cellular changes that occur in sperm while they reside in the female reproductive tract - providing a new understanding of the molecular genetics of successful fertilization.

14 Feb 2006

Intracellular observation of RNA metabolism will help identify disease-associated RNAs

For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe-in real-time-the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions.

7 Feb 2006