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University of Minnesota wins five-year CTSA award to expand effort on scientific health research

The University of Minnesota's Clinical and Translational Science Institute received more than $42 million in renewed National Institutes of Health funding through the National Center for Advancing Translational Sciences' Clinical and Translational Science Award program.

6 Apr 2018

Insights into blood cell formation may help break new ground in treatment of anemia

Every day, stem cells in our bone marrow produce billions of new red blood cells. Any disruption in this process can result in serious disease. Researchers from Charité - Universitätsmedizin Berlin and Harvard Medical School have succeeded in furthering our understanding of how blood cells are formed.

4 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis.

2 Apr 2018

Nutritionists explore the link between diet, obesity and cancer

In a special journal entry, nutritionists and other heath professionals from around the world explore the association between nutrition, obesity and cancer.

28 Mar 2018

Diabetes intervention program works well at home enviroment

A public health research team at the Brown School at Washington University in St. Louis has taken one of the most effective diabetes intervention programs and made it more accessible by partnering with an existing home-visit organization dedicated to working with mothers of preschool-aged children.

27 Mar 2018

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health, has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis.

21 Mar 2018

Wales participates in the 100,000 Genomes Project

Wales has joined the 100,000 Genomes Project, the Welsh Government announced today. The project, now a UK-wide initiative, seeks to transform patient care, encourage genomic discovery and drive a thriving genomics sector.

From Genomics England 20 Mar 2018

Moderate facebook use linked to happiness among adults with ASD

Among adults with autism spectrum disorder (ASD), a new study has shown that those who use Facebook, in moderation, are happier than those who do not.

13 Mar 2018

Study reveals key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study in Molecular Cell from scientists at Johns Hopkins Bloomberg School of Public Health.

8 Mar 2018

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

Sanford Burnham Prebys Medical Research Institute researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function.

8 Mar 2018

Researchers determine cause of difficult-to-control mitochondrial diseases

A Japanese research group has discovered that taurine is conjugated with mitochondrial transfer RNAs (tRNAs), small RNAs that decode genetic information, and that taurine deficiency in tRNA dramatically reduces both mitochondrial protein translation and impairs mitochondrial membrane integrity.

7 Mar 2018

Environmental exposures affect genes linked to respiratory diseases much more than genetic ancestry

Researchers have found strong evidence that environmental exposures, including air pollution, affect gene expressions associated with respiratory diseases much more than genetic ancestry.

6 Mar 2018

Scientists develop more cost-effective way to culture stem cells

Human pluripotent stem cells can infinitely self-renew and develop into all major cell types in the body, making them important for organ repair and replacement. But culturing them in large quantities can be expensive. Now, scientists at Japan's Kyoto University, with colleagues in India and Iran, have developed a more cost-effective culture by using a new combination of chemical compounds.

5 Mar 2018

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune system to fight cancer.

2 Mar 2018

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Dr. Alicia G. Arroyo, have identified a function of a protease that could be targeted for the treatment of some infections and even tumor metastasis.

2 Mar 2018

Study: Younger adults show memory improvement from brain stimulation, not older people

We've all asked ourselves these types of questions: Where did I leave my keys? What was his name? Where did I park my car?

1 Mar 2018

Researchers successfully graft human neural stem cells into monkeys with spinal cord injuries

Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries.

27 Feb 2018

New discovery could accelerate clinical translation of stem cell-based therapies

A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.

23 Feb 2018

CNIC researchers discover high level of plasticity among cells in regenerating zebrafish heart

Some animals, including the zebrafish, have a high capacity to regenerate tissues, allowing them to recovery fully after cardiac injury. During this process, the heart muscle cells divide to replace the damaged tissue.

11 Feb 2018