Traumatic Brain Injury News and Research

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Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue. Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking. A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

Neuren presents phase 2 clinical trial strategy for NNZ-2566

Neuren Pharmaceuticals has announced that Mr Larry Glass, Executive Vice President and head of Neuren’s US operations, has been invited by the US Army to present Neuren’s clinical trial strategy for NNZ-2566 at the Advanced Technology Applications for Combat Casualty Care (ATACCC) conference.

14 Aug 2006

Long term ibuprofen therapy given after brain injury worsens cognitive abilities

Researchers at the University of Pennsylvania School of Medicine found that chronic ibuprofen therapy given after brain injury worsens cognitive abilities.

21 Jul 2006

New research promising for improving brain cell survival after brain injury

Scientists at Melbourne's Howard Florey Institute have found a protein in the brain that can save neurons from dying after experiencing traumatic brain injury from incidents such as stroke, car accidents and falls.

10 Jul 2006

Neuren granted US patent for NNZ-2566

Neuren Pharmaceuticals has announced that its patent application entitled "GPE Analogs and Peptidomimetics" (PCT/US02/16361) has been issued in the United States (US Patent No: 7,041,314) on 9 May 2006.

10 May 2006

Researchers move closer to pinpointing age of brain activity changes related to language

The number of sites in children's brains involved in language recognition decreases as the children age, according to a University of Cincinnati (UC) study.

6 Apr 2006

Certain chemicals in the blood may indicate brain injury

Researchers at Children's Hospital of Pittsburgh have found that increased levels of certain proteins in the blood or spinal fluid may signal brain injury in infants with vomiting, fussiness and several other common symptoms.

20 Feb 2006

Novel compound stops brain cell degeneration in Alzheimer's disease

Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease.

22 Jan 2006

Traditional neck muscle resistance training may not protect athletes from head injuries

"We did see a change in the player's neck muscle strength but these changes made absolutely no difference in their ability to stabilize their heads when force was applied," said Tierney.

10 Jan 2006

Astrocytes play a direct role in controlling blood flow in the brain - influencing Alzheimer's

New findings that long-overlooked brain cells play an important role in regulating blood flow in the brain call into question one of the basic assumptions underlying today's most sophisticated brain imaging techniques and could open a new frontier when it comes to understanding Alzheimer's disease.

6 Jan 2006

Brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury

A study of patients who have difficulty paying attention to the left side of their environment has provided some of the first direct evidence that brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury.

17 Oct 2005

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

A way to detect fragments of broken brain cells that leak into the bloodstream may help doctors more quickly and precisely treat people with severe head injuries or brain diseases, say researchers at the University of Florida's McKnight Brain Institute.

17 Oct 2005

Site in the brain that controls language in right-handed people shifts with aging

...a discovery that might offer hope in the treatment of speech problems resulting from traumatic brain injury or stroke.

9 Oct 2005

Breakthrough in Alzheimer's research

This week scientists of the Flanders Interuniversity Institute for Biotechnology (VIB) will once again publish a breakthrough in their research regarding Alzheimer's disease.

3 Aug 2005

Methamphetamine users show symptoms similar to brain injury patients

Because today's methamphetamine is stronger, more potent and wreaks greater havoc on the brain, chronic users exhibit symptoms similar to patients with traumatic brain injury (TBI), according to the Brain Injury Association of Arizona (BIAAZ).

26 Jul 2005

Researchers prevent post-traumatic brain damage using experimental drug

In animal studies, researchers from Georgetown University Medical Center have shown how traumatic brain injury leads to loss of brain function - and found that an experimental drug can stop the damage and promote recovery.

18 May 2005

Moderate hypothermia is a safe treatment following traumatic brain injury in children

A first-of-its-kind multi-center trial has shown that cooling the body can have positive affects on children who suffered traumatic brain injury.

27 Apr 2005

Portable device to check for concussions

A player just took a hard knock to the head and is lying on the field. A coach rushes to his side, but the player sits up and seems fine.

27 Apr 2005

Brain-injury rehabilitation depends on acetylcholine circuitry

The ability of the brain to recover from such injury as stroke or trauma depends on a particular circuitry of neurons that "talk" to one another using the brain chemical acetylcholine, researchers led by James Conner and Mark Tuszynski in the Neural repair Group at UCSD have discovered.

20 Apr 2005

Level I trauma centers boost head injury survival

Head injury patients transferred to level I trauma centers are more likely to survive than if they're transferred to level II facilities, an Oregon Health & Science University study has found.

7 Apr 2005

Use of anti-inflammatory steroids for traumatic head injuries may actually increase the risk of death

The common use of anti-inflammatory steroids for traumatic head injuries like those from car crashes may actually increase the risk of death, according to a new review of studies about the treatment.

24 Jan 2005