Triglyceride News and Research RSS Feed - Triglyceride News and Research

Triglycerides are a type of fat in the bloodstream and fat tissue. Too much of this type of fat can contribute to the hardening and narrowing of your arteries. This puts you at risk of having a heart attack or stroke. Diseases such as diabetes, obesity, kidney failure or alcoholism can cause high triglycerides. Often, high triglycerides occur along with high levels of cholesterol, another type of fat. Triglycerides are measured along with cholesterol as part of a blood test. Normal triglyceride levels are below 150. Levels above 200 are high.
Isis Pharmaceuticals announces initiation of ISIS-SMN Rx Phase 3 study in children with SMA

Isis Pharmaceuticals announces initiation of ISIS-SMN Rx Phase 3 study in children with SMA

Isis Pharmaceuticals, Inc. announced today the initiation of a pivotal Phase 3 study evaluating ISIS-SMNRx in approximately 120 non-ambulatory children with spinal muscular atrophy (SMA). [More]
Researchers say that promoting healthy gut microbiota can help treat metabolic syndrome

Researchers say that promoting healthy gut microbiota can help treat metabolic syndrome

Promoting healthy gut microbiota, the bacteria that live in the intestine, can help treat or prevent metabolic syndrome, a combination of risk factors that increases a person's risk for heart disease, diabetes and stroke, according to researchers at Georgia State University and Cornell University. [More]
Isis receives $10 million from Biogen Idec to initiate IND-supporting studies of ISIS-BIIB3 Rx

Isis receives $10 million from Biogen Idec to initiate IND-supporting studies of ISIS-BIIB3 Rx

Isis Pharmaceuticals, Inc. announced today that it has earned a $10 million milestone payment from Biogen Idec related to the initiation of investigational new drug (IND)-supporting studies of ISIS-BIIB3Rx. ISIS-BIIB3Rx is a recently identified development candidate designed to inhibit an undisclosed target to treat a neurodegenerative disease. [More]
TSRI study points way to potential therapies for hereditary spastic paraplegia

TSRI study points way to potential therapies for hereditary spastic paraplegia

Scientists at The Scripps Research Institute have discovered that a gene mutation linked to hereditary spastic paraplegia, a disabling neurological disorder, interferes with the normal breakdown of triglyceride fat molecules in the brain. The TSRI researchers found large droplets of triglycerides within the neurons of mice modeling the disease. [More]
Metabolic abnormalities predict severe hypertension

Metabolic abnormalities predict severe hypertension

Components of the metabolic syndrome, as well as a family history of hypertension, identify people at risk of developing severe hypertension, say researchers. [More]
Magnetic resonance: A good method for detecting and quantifying fats in the liver

Magnetic resonance: A good method for detecting and quantifying fats in the liver

Obesity and overweight affect more than half of the population in our Community. Excess weight causes important alterations in the organism, one of which affects liver function. Fat accumulates in the liver producing hepatic steatosis which, in certain circumstances, causes inflammation, fibrosis and finally, cirrhosis. [More]
APOC3 gene variant dramatically reduces triglyceride levels in the blood

APOC3 gene variant dramatically reduces triglyceride levels in the blood

Research using data collected from around 4,000 healthy people in the UK has enabled scientists to identify a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. The study is the first to emerge from the UK10K Project's cohort of samples from the general public and demonstrates the power of whole genome sequencing at scale. [More]
New report outlines cholesterol-targeted approach to treat people at risk for cardiovascular disease

New report outlines cholesterol-targeted approach to treat people at risk for cardiovascular disease

A recent guideline for using statins to reduce atherosclerotic cardiovascular disease has wavered too far from the simple cholesterol goals that have saved thousands of lives in the past decade, and doesn't adequately treat patients as individuals, experts said today in a national report. [More]
Regular consumption of mango by obese adults may lower blood sugar levels

Regular consumption of mango by obese adults may lower blood sugar levels

Research published in the journal Nutrition and Metabolic Insights found that regular consumption of mango by obese adults may lower blood sugar levels and does not negatively impact body weight. [More]
Isis Pharmaceuticals begins ISIS-APOCIIIRx Phase 3 study in FCS patients

Isis Pharmaceuticals begins ISIS-APOCIIIRx Phase 3 study in FCS patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 3 study evaluating ISIS-APOCIIIRx in patients with familial chylomicronemia syndrome (FCS). FCS is a rare orphan disease, characterized by extremely high triglyceride levels, that affects an estimated 3,000 to 5,000 patients worldwide. [More]
Lifestyle impacts likelihood of developing metabolic syndrome in childhood cancer survivors

Lifestyle impacts likelihood of developing metabolic syndrome in childhood cancer survivors

A St. Jude Children's Research Hospital study found that 73 percent of adult survivors of childhood cancer more than doubled their risk of developing metabolic syndrome and related health problems by failing to follow a heart-healthy lifestyle. The results appear in the current issue of the journal Cancer. [More]
Physical fitness may buffer some of adverse health effects of too much sitting

Physical fitness may buffer some of adverse health effects of too much sitting

Physical fitness may buffer some of the adverse health effects of too much sitting, according to a new study by researchers from the American Cancer Society, The Cooper Institute, and the University of Texas. [More]
Growth hormone deficiency may protect people from developing Type 2 diabetes, cancer

Growth hormone deficiency may protect people from developing Type 2 diabetes, cancer

People who lack growth hormone (GH) receptors also appear to have marked insulin sensitivity that prevents them from developing diabetes and lowers their risk for cancer, despite their increased percentage of body fat, new research finds. [More]
African American women respond differently to anti-inflammatory effect of aspirin than white women

African American women respond differently to anti-inflammatory effect of aspirin than white women

African American women respond differently to the anti-inflammatory effect of aspirin than do white American women, new research finds. [More]
Fasting converts bad cholesterol in fat cells to energy, combating diabetes risk factors

Fasting converts bad cholesterol in fat cells to energy, combating diabetes risk factors

For prediabetics, many interventions focus on lifestyle changes and weight loss, but new research on periodic fasting has identified a biological process in the body that converts bad cholesterol in fat cells to energy, thus combating diabetes risk factors. [More]
Signs and symptoms of diabetes

Signs and symptoms of diabetes

You're approaching 50 and can't help but notice the signs of aging - your vision and hearing aren't what they used to be, and it seems your cuts and bruises take longer to heal. [More]
Physical activity may be able to prevent overweight women from developing heart disease

Physical activity may be able to prevent overweight women from developing heart disease

For otherwise healthy middle-aged women who are overweight or obese, physical activity may be their best option for avoiding heart disease, according to a study that followed nearly 900 women for seven years. [More]
Study shows commonly used statin drug does not reduce acute COPD exacerbations

Study shows commonly used statin drug does not reduce acute COPD exacerbations

A statin drug commonly used to lower cholesterol is not effective in reducing the number and severity of flare ups from chronic obstructive pulmonary disease (COPD), according to the results of a large multicenter clinical trial designed and directed by Gerard J. Criner, MD, Director of Pulmonary and Critical Care Medicine at Temple University Hospital in Philadelphia, PA. [More]
Data from phase III trials supports safety, efficacy of linagliptin in treating T2D in African-American adults

Data from phase III trials supports safety, efficacy of linagliptin in treating T2D in African-American adults

Data from a retrospective pooled analysis of eight phase III trials (two 18-week and six 24-week) of linagliptin 5 mg once-daily, showed reductions from baseline A1c at 18 (eight trials) and 24 (six trials) weeks compared to placebo in African-American adults with type 2 diabetes (T2D), [More]
Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Lipids, primarily cholesterol and triglycerides, come from two sources: what is naturally manufactured in the liver and what comes from the intestines through the diet. [More]