Tropical Disease News and Research RSS Feed - Tropical Disease News and Research

Tropical diseases encompass all diseases that occur solely, or principally, in the tropics. In practice, the term is often taken to refer to infectious diseases that thrive in hot, humid conditions, such as malaria, leishmaniasis, schistosomiasis, onchocerciasis, lymphatic filariasis, Chagas disease, African trypanosomiasis, and dengue.
New research may provide insight on how dengue virus gains entry into cells

New research may provide insight on how dengue virus gains entry into cells

Dengue fever, an infectious tropical disease caused by a mosquito-borne virus, afflicts millions of people each year, causing fever, headache, muscle and joint pains and a characteristic skin rash. In some people the disease progresses to a severe, often fatal, form known as dengue hemorrhagic fever. [More]
Researchers to highlight biomedical breakthroughs, new discoveries at Biophysical Society Meeting

Researchers to highlight biomedical breakthroughs, new discoveries at Biophysical Society Meeting

Ask a question about how the human immune system fights a tropical disease, or how viruses like HIV use genetic tricks to resist drugs, or how plant cells capture light, or how Alzheimer's takes hold in the brain, or how we can better fight diseases like cancer, or why some sperm cells are fertile while others are not, and you may have to narrow your gaze to the nanoscale to find answers. [More]
Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

An initiative is under way to develop new drugs for a devastating tropical disease that threatens almost 70 million people in Africa. [More]
USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

Animal cells similar to those of humans contain a "control room," called the centrosome, which regulates cell replication. Disrupt this core hub and you kill cell division. [More]
Researchers observe mating for the first time in microbes responsible for African sleeping sickness

Researchers observe mating for the first time in microbes responsible for African sleeping sickness

Caught in the act! Researchers from the University of Bristol have observed mating for the first time in the microbes responsible for African sleeping sickness. This tropical disease is caused by trypanosomes, single-celled parasites that are found in the blood of those afflicted. [More]
Researchers develop a class of compounds that may help eradicate Chagas disease

Researchers develop a class of compounds that may help eradicate Chagas disease

A team of researchers from Canada has developed a class of compounds which may help eradicate a neglected tropical disease that is currently hard to kill in its chronic form. The research was published ahead of print in Antimicrobial Agents and Chemotherapy. [More]
New tools for neglected diseases: an interview with Dr. BT Slingsby, CEO, GHIT Fund

New tools for neglected diseases: an interview with Dr. BT Slingsby, CEO, GHIT Fund

Nearly 3.3 billion people, a little less than half of our world’s population, are at risk of malaria, TB and what we call “neglected tropical diseases”—diseases caused by worms, parasites, viruses and bacteria like Chagas disease, river blindness, elephantiasis, sleeping sickness, etc. [More]
Scientists identify new approach to fight malaria parasites

Scientists identify new approach to fight malaria parasites

Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine and the Genomics Institute of the Novartis Research Foundation, have identified a potential new weapon and approach for attacking the parasites that cause malaria. [More]

PLOS and DNDi to launch collection of neglected tropical diseases at 10-year anniversary of DNDi

As part of a collaborative initiative, PLOS and the Drugs for Neglected Diseases initiative (DNDi) are delighted to be launching a special Collection-PLOS & DNDi: a decade of Open Access and Neglected Tropical Diseases R&D (Research and Development)-to coincide with a joint event at the Institut Pasteur in Paris celebrating the 10-year anniversary of DNDi. [More]
Findings highlight possible new approach to combat malaria

Findings highlight possible new approach to combat malaria

An international team of scientists, including researchers at Columbia University Medical Center, has identified a key metabolic enzyme that common malaria parasites require for survival at each stage of infection in humans. The findings raise the possibility of a new approach to combating malaria, one of the world's deadliest diseases. The study was published today in the online edition of the journal Nature. [More]
New concept outlines steps to tackle neglected tropical diseases, expedite poverty reduction efforts

New concept outlines steps to tackle neglected tropical diseases, expedite poverty reduction efforts

A new concept and policy framework published in PLOS NTDs outlines concrete steps for the global development community as it works to synthesize health goals with economic, environmental and social priorities. [More]
Segregating household sleeping arrangements can help prevent malaria spread

Segregating household sleeping arrangements can help prevent malaria spread

Better malaria control might come from segregating household sleeping arrangements, according to a new study co-authored by a University of Guelph professor. [More]
Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

​Researchers at Case Western Reserve University and Cleveland Clinic Lerner Research Institute have discovered recent genetic mutations in a parasite that causes over 100 million cases of malaria annually-changes that may render tens of millions of Africans who had been considered resistant, susceptible to infection. [More]
Mobilized medical care is necessary to better serve Haitian population after earthquake

Mobilized medical care is necessary to better serve Haitian population after earthquake

Three years after an earthquake killed more than 200,000 people and left an estimated 1.5 million people homeless in Haiti, a Henry Ford Hospital study found that more mobilized medical care is necessary to bridge cultural and health care barriers and better serve the Haitian population. [More]
Genetically modified bacterial treatment approach reduces or eliminates sleeping sickness

Genetically modified bacterial treatment approach reduces or eliminates sleeping sickness

A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study. [More]
PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

PaxVax Inc, which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced that it has commenced its Phase 3 clinical trial program for its single-dose oral cholera vaccine candidate, PXVX0200 (also known as CVD 103-HgR). Approximately 3,000 participants will be enrolled in this pivotal program, which is comprised of cholera challenge, safety, and immunogenicity studies. [More]

Low-cost intervention reduces transmission of lymphatic filariasis to undetectable levels

An international team of scientists have demonstrated that a simple, low-cost intervention holds the potential to eradicate a debilitating tropical disease that threatens nearly 1.4 billion people in more than six dozen countries. [More]

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

A collaboration between the Drugs for Neglected Diseases Initiative (DNDi) and the Institut Pasteur Korea (IP-K) to spur the fight against neglected diseases has been established. [More]
New research may influence development of anti-viral therapies to fight against Dengue

New research may influence development of anti-viral therapies to fight against Dengue

New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus. [More]
Men and women in Uganda face different challenges in accessing treatment for NTDs

Men and women in Uganda face different challenges in accessing treatment for NTDs

Males and females face different challenges in accessing treatment for neglected tropical diseases, according to a new study from researchers at the University of Toronto Dalla Lana School of Public Health, Uganda Ministry of Health and Imperial College London. [More]
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