Tropical Disease News and Research

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Tropical diseases encompass all diseases that occur solely, or principally, in the tropics. In practice, the term is often taken to refer to infectious diseases that thrive in hot, humid conditions, such as malaria, leishmaniasis, schistosomiasis, onchocerciasis, lymphatic filariasis, Chagas disease, African trypanosomiasis, and dengue.

PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

PaxVax Inc, which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced that it has commenced its Phase 3 clinical trial program for its single-dose oral cholera vaccine candidate, PXVX0200 (also known as CVD 103-HgR). Approximately 3,000 participants will be enrolled in this pivotal program, which is comprised of cholera challenge, safety, and immunogenicity studies.

7 Sep 2013

Low-cost intervention reduces transmission of lymphatic filariasis to undetectable levels

An international team of scientists have demonstrated that a simple, low-cost intervention holds the potential to eradicate a debilitating tropical disease that threatens nearly 1.4 billion people in more than six dozen countries.

22 Aug 2013

A*STAR's SIgN discovers new strategy to develop universal dengue vaccine

A new strategy that cripples the ability of the dengue virus to escape the host immune system has been discovered by A*STAR's Singapore Immunology Network. This breakthrough strategy opens a door of hope to what may become the world's first universal dengue vaccine candidate that can give full protection from all four serotypes of the dreadful virus.

14 Aug 2013

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

A collaboration between the Drugs for Neglected Diseases Initiative (DNDi) and the Institut Pasteur Korea (IP-K) to spur the fight against neglected diseases has been established.

14 Aug 2013

SIgN discovers strategy that cripples ability of dengue virus to escape host immune system

A new strategy that cripples the ability of the dengue virus to escape the host immune system has been discovered by A*STAR's Singapore Immunology Network (SIgN). This breakthrough strategy opens a door of hope to what may become the world's first universal dengue vaccine candidate that can give full protection from all four serotypes of the dreadful virus.

14 Aug 2013

Complex and messy ethical, social and cultural issues often left on table

Resolving complex ethical, social and cultural issues in the early stage of a global health research project or clinical trial can improve the impact and quality of that research, a new report says.

12 Aug 2013

New research may influence development of anti-viral therapies to fight against Dengue

New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.

3 Aug 2013

New needle-free treatment may dramatically reduce global snakebite fatalities

A team of researchers led by Dr. Matt Lewin of the California Academy of Sciences, in collaboration with the Department of Anesthesia at the University of California, San Francisco, has pioneered a novel approach to treating venomous snakebites-administering antiparalytics topically via a nasal spray.

31 Jul 2013

Men and women in Uganda face different challenges in accessing treatment for NTDs

Males and females face different challenges in accessing treatment for neglected tropical diseases, according to a new study from researchers at the University of Toronto Dalla Lana School of Public Health, Uganda Ministry of Health and Imperial College London.

15 Jul 2013

Liverpool School of Tropical Medicine receives US$ 10 million to continue research against human filariasis

Liverpool School of Tropical Medicine (LSTM) has received US$ 10 million from the Bill & Melinda Gates Foundation to continue their breakthrough drug discovery and development research against human filariasis - parasitic worm infections which cause river blindness and elephantiasis, some of the world’s most debilitating diseases affecting up to 150 million people in 83 countries throughout the tropics.

1 Jul 2013

Weill Cornell researchers discover high burden of hypertension in sub-Saharan African country

Based on the experience of a large hospital in Tanzania, Weill Cornell Medical College researchers have discovered a "startlingly" high burden of hypertension in this sub-Saharan African country.

26 Jun 2013

Researchers identify new virus in patients with severe brain infections

Researchers have identified a new virus in patients with severe brain infections in Vietnam. Further research is needed to determine whether the virus is responsible for the symptoms of disease.

18 Jun 2013

NanoViricides files Orphan Drug application with FDA for DengueCide

NanoViricides, Inc. announced today that it has filed an Orphan Drug application with the Office of Orphan Product Development of the US FDA for DengueCide, its drug candidate for the treatment of dengue and dengue hemorrhagic fever.

10 Jun 2013

Sustained engagement, partnership needed to implement new treatments for neglected diseases

Days after two landmark resolutions were adopted at the World Health Assembly - on neglected tropical diseases and on research and development, financing and coordination for the health needs of developing countries - over 400 scientists, representatives and ministers of health, ambassadors, national control programme representatives, African regulators, health workers, public health experts, and activists from 21 African countries and 10 others from around the world gather in Nairobi to take stock of health innovation for neglected diseases in Africa over the past decade.

6 Jun 2013

Weather may influence transmission of West Nile, chikungunya, and other viral disease

Urban epidemics resulting from viral diseases, such as West Nile fever and chikungunya fever, are transmitted by infected mosquitoes.

4 Jun 2013

Queen's University Belfast scientists awarded research grants to tackle tropical diseases

Queen's University Belfast has been announced as a Grand Challenges Explorations winner, an initiative founded by the Bill & Melinda Gates Foundation. Scientists at the University's Institute for Global Food Security have been awarded grants to pursue two Innovative global health and development research projects aimed at tackling tropical diseases.

31 May 2013

Lindsley F. Kimball Research Institute receives grant for global health and development research project

The Lindsley F. Kimball Research Institute of the New York Blood Center announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

22 May 2013

New diagnostic test for lymphatic filariasis

A new diagnostic test for a worm infection that can lead to severe enlargement and deformities of the legs and genitals is far more sensitive than the currently used test, according to results of a field study in Liberia, in West Africa, where the infection is endemic.

21 May 2013

New LAMP malaria test to improve diagnosis for imported UK cases

A new, highly sensitive blood test that quickly detects even the lowest levels of malaria parasites in the body could make a dramatic difference in efforts to tackle the disease in the UK and across the world, according to new research published in the Journal of Infectious Diseases.

17 May 2013

Research findings have implications for understanding how to slow spread of dengue virus

Researchers have identified the dose of dengue virus in human blood that is required to infect mosquitoes when they bite. Mosquitoes are essential for transmitting the virus between people so the findings have important implications for understanding how to slow the spread of the disease.

14 May 2013

Tropical Disease News and Research

Further Reading

PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

Low-cost intervention reduces transmission of lymphatic filariasis to undetectable levels

A*STAR's SIgN discovers new strategy to develop universal dengue vaccine

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

SIgN discovers strategy that cripples ability of dengue virus to escape host immune system

Complex and messy ethical, social and cultural issues often left on table

New research may influence development of anti-viral therapies to fight against Dengue

New needle-free treatment may dramatically reduce global snakebite fatalities

Men and women in Uganda face different challenges in accessing treatment for NTDs

Liverpool School of Tropical Medicine receives US$ 10 million to continue research against human filariasis

Weill Cornell researchers discover high burden of hypertension in sub-Saharan African country

Researchers identify new virus in patients with severe brain infections

NanoViricides files Orphan Drug application with FDA for DengueCide

Sustained engagement, partnership needed to implement new treatments for neglected diseases

Weather may influence transmission of West Nile, chikungunya, and other viral disease

Queen's University Belfast scientists awarded research grants to tackle tropical diseases

Lindsley F. Kimball Research Institute receives grant for global health and development research project

New diagnostic test for lymphatic filariasis

New LAMP malaria test to improve diagnosis for imported UK cases

Research findings have implications for understanding how to slow spread of dengue virus

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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