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Research sheds new light on the development of HPV-associated cancer

Research sheds new light on the development of HPV-associated cancer

It's long been known that certain strains of human papillomavirus (HPV) cause cancer. Now, researchers at The Ohio State University have determined a new way that HPV might spark cancer development - by disrupting the human DNA sequence with repeating loops when the virus is inserted into host-cell DNA as it replicates. [More]
Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Neuroblastoma is one of the deadliest childhood cancers, accounting for 15 percent of pediatric cancer deaths. For patients with high-risk neuroblastomas, the five-year survival rate is 40 to 50 percent even with the most rigorous treatments available today. [More]
Physicist creates luminescent nanoparticle to use in photodynamic cancer therapy

Physicist creates luminescent nanoparticle to use in photodynamic cancer therapy

A University of Texas at Arlington physicist working to create a luminescent nanoparticle to use in security-related radiation detection may have instead happened upon an advance in photodynamic cancer therapy. [More]
Study proposes new model for understanding how proteins bind together to facilitate cell movement

Study proposes new model for understanding how proteins bind together to facilitate cell movement

Cell movement plays an important role in a host of biological functions from embryonic development to repairing wounded tissue. It also enables cancer cells to break free from their sites of origin and migrate throughout the body. [More]
Researchers coax human embryonic stem cells to turn into working spinal cord cells

Researchers coax human embryonic stem cells to turn into working spinal cord cells

The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become, a University of Michigan study shows. [More]

New fiber-optic device helps clinicians diagnose cancer at early-stage

An engineering researcher at the University of Arkansas has developed an inexpensive, endoscopic microscope capable of producing high-resolution, sub-cellular images of tissue in real time. [More]
New blood test accurately detects presence of breast cancer and monitors response to treatment

New blood test accurately detects presence of breast cancer and monitors response to treatment

Johns Hopkins Kimmel Cancer Center investigators report they have designed a blood test that accurately detects the presence of advanced breast cancer and also holds promise for precisely monitoring response to cancer treatment. [More]
EventusDx completes $2.72M financing to support development, commercialization of Octava breast cancer tests

EventusDx completes $2.72M financing to support development, commercialization of Octava breast cancer tests

Eventus Diagnostics, Inc. today announced completion of a $2.72 million financing. The financing was led by a new family office private investor, and existing investors also participated. Proceeds of the financing will mostly be used to support the continued development and commercialization of the company's Octava breast cancer tests. [More]
Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

A phase III clinical trial conducted at the Meir Medical Center in Kfar-Saba, Israel is now recruiting participants to study the effects of dietary supplement PectaSol-C modified citrus pectin (MCP) in controlling prostate specific antigen (PSA) levels in prostate cancer patients. [More]
New data focuses on different approaches to improve diagnosis and treatment of HCC

New data focuses on different approaches to improve diagnosis and treatment of HCC

Epidemiological, genetic and clinical data presented today at the International Liver CongressTM 2014 are collectively focussed on different approaches designed to improve the diagnosis, staging and treatment of hepatocellular carcinoma (HCC). [More]

New technique of single-cell genomic analysis to reverse tissue engineering

Consider the marvel of the embryo. It begins as a glob of identical cells that change shape and function as they multiply to become the cells of our lungs, muscles, nerves and all the other specialized tissues of the body. [More]

Vivolux receives FDA clearance to proceed with phase I/II clinical trial of VLX600

Vivolux AB, a drug discovery company specialized in cancer treatment, announced today that the FDA has granted clearance to proceed with VLX600 into the clinical phase I/II. VLX600 is one of the company's promising projects, and which was recently published in the journal Nature Communications. [More]
Johns Hopkins designs blood test that accurately detects presence of advanced breast cancer

Johns Hopkins designs blood test that accurately detects presence of advanced breast cancer

Johns Hopkins Kimmel Cancer Center investigators report they have designed a blood test that accurately detects the presence of advanced breast cancer and also holds promise for precisely monitoring response to cancer treatment. [More]

New study identifies potential target for colorectal cancer treatment

A new study identifies a molecule that is a probable driving force in colorectal cancer and suggests that the molecule could be an important target for colorectal cancer treatment and a valuable biomarker of tumor progression. [More]
Researchers investigate role of microRNAs in breast cancer cells

Researchers investigate role of microRNAs in breast cancer cells

Metastasis — the spreading of cancer cells from a primary tumor site to other parts of the body — generally leads to poorer outcomes for patients, so oncologists and researchers are constantly seeking new ways to detect and thwart this malicious process. [More]

Nanotechnology unlocks new pathways for targeted drug delivery

​Significant advances have been made in chemotherapy over the past decade, but targeting drugs to cancer cells while avoiding healthy tissues continues to be a major challenge. [More]
Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

​Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms. [More]
Ceritinib ‘highly active’ in advanced ALK-rearranged NSCLC

Ceritinib ‘highly active’ in advanced ALK-rearranged NSCLC

Phase I study findings suggest the investigational drug ceritinib is effective in patients with advanced non-small-cell lung cancer with anaplastic lymphoma kinase gene rearrangement, even in those who develop resistance to crizotinib. [More]

Two candidate mTOR therapy biomarkers identified in RCC

Two genes, TSC1 and MTOR, warrant further investigation as biomarkers for treatment benefit with rapalogs in patients with renal cell carcinoma, indicate study results published in Clinical Cancer Research. [More]

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

In 10% of human tumors there is a family history of hereditary disease associated with mutations in identified genes. The best examples are the cases of polyps in the large intestine associated with the APC gene and breast cancer associated with BRCA1 and BRCA2 genes. [More]