Uric Acid News and Research

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Low doses of a less commonly used drug may be a better treatment option for gout

Gout occurs when urate crystals accumulate in the joints, and xanthine oxidase inhibitors such as febuxostat are a mainstay of therapy to help reduce blood urate levels in affected patients.

7 Jul 2022

‘Smart’ diaper could provide painless and quick bedside urinalyses

Urine can reveal a lot about a person's health. But physicians don't currently have a convenient or fast way of tracking the concentration of important compounds in their patients' urine.

5 May 2022

Probenecid shows activity against respiratory syncytial virus

A new study describes the antiviral activity of the approved drug probenecid against respiratory syncytial virus.

29 Apr 2022

PM2.5 reduction may have a beneficial effect on kidney function

Air pollution has significant toxicity on the kidney. However, improving air condition may have a beneficial effect on kidney function, according to a population-based study published in Health Data Science, a Science Partner Journal.

18 Feb 2022

Trial of early antiviral therapy for COVID-19 shows no significant benefit

A new preprint research paper examines the efficacy of using three antivirals in various combinations in early infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Feb 2022

Innovative coating kills SARS-CoV-2 and E. coli

Researchers develop a low-cost, non-toxic, and scalable antimicrobial polymer that can be functionalized on diverse fabrics.

16 Feb 2022

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

BioIVT, a leading provider of research models and services for drug and diagnostic development, is hosting a webinar in which researchers will discuss how they used a sandwich-cultured human hepatocyte (SCHH) model to investigate the drug-drug interaction (DDI) potential of bempedoic acid, a drug that was recently approved to treat hypercholesterolemia.

9 Nov 2021

NUS scientists develop a smart bandage to monitor chronic wounds

A research team led by Professor Lim Chwee Teck from the National University of Singapore's Department of Biomedical Engineering and Institute for Health Innovation & Technology, in collaboration with clinical partners from Singapore General Hospital, has developed a smart wearable sensor that can conduct real-time, point-of-care assessment of chronic wounds wirelessly via an app.

21 Oct 2021

Researchers explore the fate of dietary fructose in the body

In today's fast-paced world, the dependence on the widely available "fast" foods and beverages has risen. These foods are typically low in fiber and essential nutrients, and often consist of high amounts of added sugar. This shift in dietary trends, accompanied by a sedentary lifestyle, has been attributed to the rise in various metabolic disorders like diabetes, fatty liver disease, and heart disease.

31 Aug 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

Combining two medications doubles gout treatment success, study reveals

By combining two medications, researchers at Michigan Medicine optimized a therapy for people with gout, a condition that causes severe damage and disability if left untreated.

11 May 2021

New wearable sensor can track healing in chronic skin wounds

Researchers from Skoltech and the University of Texas at Austin have presented a proof-of-concept for a wearable sensor that can track healing in sores, ulcers, and other kinds of chronic skin wounds, even without the need to remove the bandages.

2 Dec 2020

Telemedicine appointment cancellations were almost zero during the COVID phase

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that expanded use of telemedicine during the COVID-19 pandemic improved cancellation rates, no-shows and completed medical visits for rheumatology ambulatory clinics in one large Ohio health system.

9 Nov 2020

Extreme levels of serum uric acid linked to substantial reduction in patient survival

Extreme values of serum uric acid levels in the blood can markedly reduce a patient's chance of surviving and reduce their lifespans by up to 11 years, according to a new study by researchers at University of Limerick's School of Medicine.

4 Nov 2020

New multiplexed test with a low-cost sensor may enable at-home COVID diagnosis

One feature of the COVID-19 virus that makes it so difficult to contain is that it can be easily spread to others by a person who has yet to show any signs of infection.

1 Oct 2020

High fructose corn syrup increases risk factors for heart disease, diabetes

Consuming high fructose corn syrup appears to be as bad for your health as consuming sugar in the form of fructose alone, according to a new study from researchers at the University of California, Davis.

18 Sep 2020

A wearable sensor printed on natural polymer for monitoring body fluids present in sweat

A wearable sensor printed on microbial nanocellulose, a natural polymer, has been created in Brazil by researchers at the University of São Paulo in São Carlos in collaboration with colleagues at São Paulo State University in Araraquara, the University of Araraquara, the University of Campinas, and the Brazilian National Nanotechnology Laboratory.

17 Aug 2020

Chronic kidney disease medication doesn’t work, shows study

A major clinical trial from the University of New South Wales (UNSW) reports that a medication called allopurinol, which is prescribed to about 20% of patients with chronic kidney disease (CKD), doesn’t work as expected. The results are published in the New England Journal of Medicine on June 25, 2020.

28 Jun 2020

Study shows generic drug does not slow kidney disease

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure, requiring dialysis treatment or kidney transplantation for survival, according to a study in Diabetes Care.

26 Jun 2020

Promising treatment does not guard against complication in type 1 diabetes

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival.

25 Jun 2020